Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8U3J1

- EI2BL_PYRFU

UniProt

Q8U3J1 - EI2BL_PYRFU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative translation initiation factor eIF-2B subunit 2-like

Gene

PF0475

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the exchange of initiation factor 2-bound GDP for GTP.By similarity

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Putative translation initiation factor eIF-2B subunit 2-like
Alternative name(s):
eIF-2B GDP-GTP exchange factor
Gene namesi
Ordered Locus Names:PF0475
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000001013: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276Putative translation initiation factor eIF-2B subunit 2-likePRO_0000156108Add
BLAST

Proteomic databases

PRIDEiQ8U3J1.

Interactioni

Subunit structurei

Complex of two different subunits.Curated

Protein-protein interaction databases

STRINGi186497.PF0475.

Structurei

3D structure databases

ProteinModelPortaliQ8U3J1.
SMRiQ8U3J1. Positions 2-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1184.
HOGENOMiHOG000224731.
KOiK03680.
OMAiNPTMASL.

Family and domain databases

Gene3Di1.20.120.420. 1 hit.
InterProiIPR000649. IF-2B-related.
IPR027363. M1Pi_N.
[Graphical view]
PfamiPF01008. IF-2B. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8U3J1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLPEKVVKIL EEMKNEKIRG ASWMAKKGAE AFILLSEELD ETSLEEGIIE
60 70 80 90 100
LKREILEINP SMASLYNLAM FIPITNDREV VKLRAEEFIK RAEEAKKEIA
110 120 130 140 150
SIGAQLIDSG DVIITHSYSS AVFEILKTAK RRGKQFKVIL TESAPDYEGL
160 170 180 190 200
YLAKALQDES IEVEIITDAQ LGLFAKDATL AIVGADTVTK DGYVVNKAGT
210 220 230 240 250
YLLAISCYES EVPFYVAAET YKFHQKITSK EVELVERPLY REGSRVRNVL
260 270
FDITPWKFIR GIITELGIIL PPRDMI
Length:276
Mass (Da):31,097
Last modified:June 1, 2002 - v1
Checksum:iB57A8C3D27A8A294
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009950 Genomic DNA. Translation: AAL80599.1.
RefSeqiNP_578204.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL80599; AAL80599; PF0475.
GeneIDi1468316.
KEGGipfu:PF0475.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009950 Genomic DNA. Translation: AAL80599.1 .
RefSeqi NP_578204.1. NC_003413.1.

3D structure databases

ProteinModelPortali Q8U3J1.
SMRi Q8U3J1. Positions 2-275.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 186497.PF0475.

Proteomic databases

PRIDEi Q8U3J1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL80599 ; AAL80599 ; PF0475 .
GeneIDi 1468316.
KEGGi pfu:PF0475.

Phylogenomic databases

eggNOGi COG1184.
HOGENOMi HOG000224731.
KOi K03680.
OMAi NPTMASL.

Family and domain databases

Gene3Di 1.20.120.420. 1 hit.
InterProi IPR000649. IF-2B-related.
IPR027363. M1Pi_N.
[Graphical view ]
Pfami PF01008. IF-2B. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
    Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
    Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Entry informationi

Entry nameiEI2BL_PYRFU
AccessioniPrimary (citable) accession number: Q8U3J1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: June 1, 2002
Last modified: October 1, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3