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Protein

Putative translation initiation factor eIF-2B subunit 2-like

Gene

PF0475

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the exchange of initiation factor 2-bound GDP for GTP.By similarity

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Putative translation initiation factor eIF-2B subunit 2-like
Alternative name(s):
eIF-2B GDP-GTP exchange factor
Gene namesi
Ordered Locus Names:PF0475
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001561081 – 276Putative translation initiation factor eIF-2B subunit 2-likeAdd BLAST276

Proteomic databases

PRIDEiQ8U3J1

Interactioni

Subunit structurei

Complex of two different subunits.Curated

Protein-protein interaction databases

STRINGi186497.PF0475

Structurei

3D structure databases

ProteinModelPortaliQ8U3J1
SMRiQ8U3J1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG01125 Archaea
COG1184 LUCA
HOGENOMiHOG000224731
KOiK03680
OMAiVFENEFR
OrthoDBiPOG093Z06II

Family and domain databases

Gene3Di1.20.120.420, 1 hit
InterProiView protein in InterPro
IPR000649 IF-2B-related
IPR027363 M1Pi_N
IPR037171 NagB/RpiA_transferase-like
PfamiView protein in Pfam
PF01008 IF-2B, 1 hit
SUPFAMiSSF100950 SSF100950, 1 hit

Sequencei

Sequence statusi: Complete.

Q8U3J1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPEKVVKIL EEMKNEKIRG ASWMAKKGAE AFILLSEELD ETSLEEGIIE
60 70 80 90 100
LKREILEINP SMASLYNLAM FIPITNDREV VKLRAEEFIK RAEEAKKEIA
110 120 130 140 150
SIGAQLIDSG DVIITHSYSS AVFEILKTAK RRGKQFKVIL TESAPDYEGL
160 170 180 190 200
YLAKALQDES IEVEIITDAQ LGLFAKDATL AIVGADTVTK DGYVVNKAGT
210 220 230 240 250
YLLAISCYES EVPFYVAAET YKFHQKITSK EVELVERPLY REGSRVRNVL
260 270
FDITPWKFIR GIITELGIIL PPRDMI
Length:276
Mass (Da):31,097
Last modified:June 1, 2002 - v1
Checksum:iB57A8C3D27A8A294
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA Translation: AAL80599.1
RefSeqiWP_011011592.1, NC_003413.1

Genome annotation databases

EnsemblBacteriaiAAL80599; AAL80599; PF0475
GeneIDi1468316
KEGGipfu:PF0475
PATRICifig|186497.12.peg.499

Similar proteinsi

Entry informationi

Entry nameiEI2BL_PYRFU
AccessioniPrimary (citable) accession number: Q8U3J1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: June 1, 2002
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health