Q8U3D2 (Q8U3D2_PYRFU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL AAL80661.1

Gene names

Ordered Locus Names:

PF0537

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Taxonomic identifier

186497 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	770 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1Z26 PDB 1U04 PDB 1Z25 Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8U3D2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: E68D7618C3FC7D6D	FASTA	770	90,390
	10 20 30 40 50 60 MKAKVVINLV KINKKIIPDK IYVYRLFNDP EEELQKEGYS IYRLAYENVG IVIDPENLII 70 80 90 100 110 120 ATTKELEYEG EFIPEGEISF SELRNDYQSK LVLRLLKENG IGEYELSKLL RKFRKPKTFG 130 140 150 160 170 180 DYKVIPSVEM SVIKHDEDFY LVIHIIHQIQ SMKTLWELVN KDPKELEEFL MTHKENLMLK 190 200 210 220 230 240 DIASPLKTVY KPCFEEYTKK PKLDHNQEIV KYWYNYHIER YWNTPEAKLE FYRKFGQVDL 250 260 270 280 290 300 KQPAILAKFA SKIKKNKNYK IYLLPQLVVP TYNAEQLESD VAKEILEYTK LMPEERKELL 310 320 330 340 350 360 ENILAEVDSD IIDKSLSEIE VEKIAQELEN KIRVRDDKGN SVPISQLNVQ KSQLLLWTNY 370 380 390 400 410 420 SRKYPVILPY EVPEKFRKIR EIPMFIILDS GLLADIQNFA TNEFRELVKS MYYSLAKKYN 430 440 450 460 470 480 SLAKKARSTN EIGLPFLDFR GKEKVITEDL NSDKGIIEVV EQVSSFMKGK ELGLAFIAAR 490 500 510 520 530 540 NKLSSEKFEE IKRRLFNLNV ISQVVNEDTL KNKRDKYDRN RLDLFVRHNL LFQVLSKLGV 550 560 570 580 590 600 KYYVLDYRFN YDYIIGIDVA PMKRSEGYIG GSAVMFDSQG YIRKIVPIKI GEQRGESVDM 610 620 630 640 650 660 NEFFKEMVDK FKEFNIKLDN KKILLLRDGR ITNNEEEGLK YISEMFDIEV VTMDVIKNHP 670 680 690 700 710 720 VRAFANMKMY FNLGGAIYLI PHKLKQAKGT PIPIKLAKKR IIKNGKVEKQ SITRQDVLDI 730 740 750 760 770 FILTRLNYGS ISADMRLPAP VHYAHKFANA IRNEWKIKEE FLAEGFLYFV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Crystal structure of Argonaute and its implications for RISC slicer activity." Song J.J., Smith S.K., Hannon G.J., Joshua-Tor L. Science 305:1434-1437(2004) [PubMed: 15284453] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS).
[2]	"Purified Argonaute2 and an siRNA form recombinant human RISC." Rivas F.V., Tolia N.H., Song J.-J., Aragon J.P., Liu J., Hannon G.J., Joshua-Tor L. Nat. Struct. Mol. Biol. 12:340-349(2005) [PubMed: 15800637] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS).
[3]	"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009950 Genomic DNA. Translation: AAL80661.1.

RefSeq

NP_578266.1. NC_003413.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1U04	X-ray	2.25	A	1-770	[»]
1Z25	X-ray	2.70	A	1-770	[»]
1Z26	X-ray	2.50	A	1-770	[»]

ProteinModelPortal

Q8U3D2.

SMR

Q8U3D2. Positions 1-770.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBPYRT00000006038; EBPYRP00000005899; EBPYRG00000006037.

GeneID

1468378.

GenomeReviews

Gene locus PF0537 in contig AE009950_GR.

KEGG

pfu:PF0537.

NMPDR

fig|186497.1.peg.549.

Phylogenomic databases

OMA

KINESIM.

ProtClustDB

CLSK214007.

Family and domain databases

InterPro

IPR003100. PAZ.
IPR003165. Piwi.
IPR012337. RNaseH-like_dom.
IPR021103. siRNA-bd_Argonaute.
[Graphical view]

KO

K07578.

Pfam

PF12212. PAZ_siRNAbind. 1 hit.
PF02171. Piwi. 1 hit.
[Graphical view]

SMART

SM00950. Piwi. 1 hit.
[Graphical view]

SUPFAM

SSF101690. PAZ. 1 hit.
SSF53098. RNaseH_fold. 1 hit.

PROSITE

PS50822. PIWI. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8U3D2_PYRFU

Accession

Primary (citable) accession number: Q8U3D2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)