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Protein
Submitted name:

RNase l inhibitor

Gene

PF0670

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei83ADPCombined sources1
Binding sitei88ADPCombined sources1
Binding sitei349ADPCombined sources1
Binding sitei417ADPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi106 – 113ATPPROSITE-ProRule annotation8
Nucleotide bindingi109 – 114ADPCombined sources6
Nucleotide bindingi371 – 378ATPPROSITE-ProRule annotation8
Nucleotide bindingi374 – 379ADPCombined sources6

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
RNase l inhibitorImported
Gene namesi
Ordered Locus Names:PF0670Imported
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)Imported
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi79 ↔ 128Combined sources

Proteomic databases

PRIDEiQ8U306.

Interactioni

Protein-protein interaction databases

STRINGi186497.PF0670.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YQTX-ray1.90A73-590[»]
ProteinModelPortaliQ8U306.
SMRiQ8U306.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8U306.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 354Fe-4S ferredoxin-typeInterPro annotationAdd BLAST34
Domaini42 – 714Fe-4S ferredoxin-typeInterPro annotationAdd BLAST30
Domaini66 – 309ABC transporterInterPro annotationAdd BLAST244
Domaini334 – 554ABC transporterInterPro annotationAdd BLAST221

Phylogenomic databases

eggNOGiarCOG00187. Archaea.
COG1245. LUCA.
HOGENOMiHOG000222803.
KOiK06174.
OMAiISYKPQY.
OrthoDBiPOG093Z00XY.

Family and domain databases

CDDicd03236. ABC_RNaseL_inhibitor_domain1. 1 hit.
InterProiView protein in InterPro
IPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
IPR013283. RLI1.
IPR034348. RLI_dom_1.
IPR007209. RNaseL-inhib_metal-bd_dom.
PANTHERiPTHR19248. PTHR19248. 1 hit.
PfamiView protein in Pfam
PF00005. ABC_tran. 2 hits.
PF00037. Fer4. 1 hit.
PF04068. RLI. 1 hit.
PRINTSiPR01868. ABCEFAMILY.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8U306-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIAVIDYDK CNPDKCGHFL CERVCPVNRM GGEAIIIDEE NYKPIIQEAS
60 70 80 90 100
CTGCGICVHK CPFKAISIVN LPEQLEEDCV HRYGVNAFVL YRLPVVKEGM
110 120 130 140 150
VVGIVGPNGT GKSTAVKILA GQLIPNLCGD NDSWDGVIRA FRGNELQNYF
160 170 180 190 200
EKLKNGEIRP VVKPQYVDLI PKAVKGKVIE LLKKADETGK LEEVVKALEL
210 220 230 240 250
ENVLDREIQH LSGGELQRVA IAAALLRNAT FYFFDEPSSY LDIRQRLNAA
260 270 280 290 300
RAIRRLSEEG KSVLVVEHDL AVLDYLSDII HVVYGEPGVY GIFSQPKGTR
310 320 330 340 350
NGINEFLRGY LKDENVRFRP YEIKFTKTGE RVEIERETLV TYPRLVKDYG
360 370 380 390 400
SFRLEVEPGE IKKGEVIGIV GPNGIGKTTF VKMLAGVEEP TEGKIEWDLT
410 420 430 440 450
VAYKPQYIKA DYEGTVYELL SKIDASKLNS NFYKTELLKP LGIIDLYDRE
460 470 480 490 500
VNELSGGELQ RVAIAATLLR DADIYLLDEP SAYLDVEQRL AVSRAIRHLM
510 520 530 540 550
EKNEKTALVV EHDVLMIDYV SDRLMVFEGE PGKYGRALPP MGMREGMNRF
560 570 580 590
LASIGITFRR DPDTGRPRAN KEGSVKDREQ KEKGEYYYIA
Length:590
Mass (Da):66,456
Last modified:June 1, 2002 - v1
Checksum:i7325414D98FA7266
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80794.1.
RefSeqiWP_011011791.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL80794; AAL80794; PF0670.
GeneIDi1468515.
KEGGipfu:PF0670.
PATRICifig|186497.12.peg.705.

Similar proteinsi

Entry informationi

Entry nameiQ8U306_PYRFU
AccessioniPrimary (citable) accession number: Q8U306
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: August 30, 2017
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported