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Protein
Submitted name:

N-type ATP pyrophosphatase superfamily

Gene

PF0828

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei37ATP; via amide nitrogen and carbonyl oxygenCombined sources1
Binding sitei48ATPCombined sources1
Binding sitei97AMP; via amide nitrogen and carbonyl oxygenCombined sources1
Binding sitei97ATP; via amide nitrogenCombined sources1
Binding sitei104ATPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17AMPCombined sources8
Nucleotide bindingi10 – 17ATPCombined sources8
Nucleotide bindingi188 – 189ATPCombined sources2

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-bindingCombined sources, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
N-type ATP pyrophosphatase superfamilyImported
Gene namesi
Ordered Locus Names:PF0828Imported
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)Imported
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8U2K6.

Interactioni

Protein-protein interaction databases

STRINGi186497.PF0828.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RJZX-ray2.30A1-229[»]
3RK0X-ray2.40A1-229[»]
3RK1X-ray2.30A/B1-229[»]
ProteinModelPortaliQ8U2K6.
SMRiQ8U2K6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8U2K6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 212Diphthami_syn_2InterPro annotationAdd BLAST206

Phylogenomic databases

eggNOGiarCOG00035. Archaea.
COG2102. LUCA.
HOGENOMiHOG000229449.
OMAiCIANGHE.

Family and domain databases

CDDicd01994. Alpha_ANH_like_IV. 1 hit.
Gene3Di3.40.50.620. 1 hit.
InterProiIPR002761. Diphthami_syn_dom.
IPR030662. DPH6/MJ0570.
IPR005237. MJ0570.
IPR022427. MJ0570_ATP-bd.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR12196. PTHR12196. 1 hit.
PfamiPF01902. Diphthami_syn_2. 1 hit.
[Graphical view]
PIRSFiPIRSF039123. Diphthamide_synthase. 1 hit.
TIGRFAMsiTIGR03679. arCOG00187. 1 hit.
TIGR00290. MJ0570_dom. 1 hit.
TIGR00289. TIGR00289. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8U2K6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGLADVAVL YSGGKDSNYA LYWAIKNRFS VKFLVTMVSE NEESYMYHTI
60 70 80 90 100
NANLTDLQAR ALGIPLVKGF TQGEKEKEVE DLKRVLSGLK IQGIVAGALA
110 120 130 140 150
SKYQRKRIEK VAKELGLEVY TPAWGRDAKE YMRELLNLGF KIMVVGVSAY
160 170 180 190 200
GLDESWLGRI LDESALEELI TLNEKYKVHV AGEGGEFETF VLDMPLFKYK
210 220
IVVDKAKKVW EPCTSSGKLI IEEAHLESK
Length:229
Mass (Da):25,721
Last modified:June 1, 2002 - v1
Checksum:iC0EFAE0E35A69FA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80952.1.
RefSeqiWP_011011957.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL80952; AAL80952; PF0828.
GeneIDi1468684.
KEGGipfu:PF0828.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL80952.1.
RefSeqiWP_011011957.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3RJZX-ray2.30A1-229[»]
3RK0X-ray2.40A1-229[»]
3RK1X-ray2.30A/B1-229[»]
ProteinModelPortaliQ8U2K6.
SMRiQ8U2K6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF0828.

Proteomic databases

PRIDEiQ8U2K6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL80952; AAL80952; PF0828.
GeneIDi1468684.
KEGGipfu:PF0828.

Phylogenomic databases

eggNOGiarCOG00035. Archaea.
COG2102. LUCA.
HOGENOMiHOG000229449.
OMAiCIANGHE.

Miscellaneous databases

EvolutionaryTraceiQ8U2K6.

Family and domain databases

CDDicd01994. Alpha_ANH_like_IV. 1 hit.
Gene3Di3.40.50.620. 1 hit.
InterProiIPR002761. Diphthami_syn_dom.
IPR030662. DPH6/MJ0570.
IPR005237. MJ0570.
IPR022427. MJ0570_ATP-bd.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR12196. PTHR12196. 1 hit.
PfamiPF01902. Diphthami_syn_2. 1 hit.
[Graphical view]
PIRSFiPIRSF039123. Diphthamide_synthase. 1 hit.
TIGRFAMsiTIGR03679. arCOG00187. 1 hit.
TIGR00290. MJ0570_dom. 1 hit.
TIGR00289. TIGR00289. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ8U2K6_PYRFU
AccessioniPrimary (citable) accession number: Q8U2K6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: November 2, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.