SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8U260

- SYFB_PYRFU

UniProt

Q8U260 - SYFB_PYRFU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phenylalanine--tRNA ligase beta subunit

Gene
pheT, PF0990
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. phenylalanine-tRNA ligase activity Source: UniProtKB-HAMAP
  4. tRNA binding Source: InterPro

GO - Biological processi

  1. phenylalanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunit (EC:6.1.1.20)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunit
Short name:
PheRS
Gene namesi
Name:pheT
Ordered Locus Names:PF0990
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
ProteomesiUP000001013: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 556556Phenylalanine--tRNA ligase beta subunitUniRule annotationPRO_0000127008Add
BLAST

Proteomic databases

PRIDEiQ8U260.

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits By similarity.

Protein-protein interaction databases

IntActiQ8U260. 1 interaction.
STRINGi186497.PF0990.

Structurei

3D structure databases

ProteinModelPortaliQ8U260.
SMRiQ8U260. Positions 2-349.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini278 – 35477B5Add
BLAST

Sequence similaritiesi

Contains 1 B5 domain.

Phylogenomic databases

eggNOGiCOG0072.
HOGENOMiHOG000105094.
KOiK01890.
OMAiNTHRSYP.

Family and domain databases

Gene3Di3.30.56.20. 1 hit.
HAMAPiMF_00284. Phe_tRNA_synth_beta2.
InterProiIPR005146. B3/B4_tRNA-bd.
IPR009061. DNA-bd_dom_put.
IPR004531. Phe-tRNA-synth_IIc_bsu_arc.
IPR020825. Phe-tRNA_synthase_B3/B4.
IPR022918. Phe_tRNA_ligase_beta2_bac/arc.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR005147. tRNA_synthase_B5-dom.
[Graphical view]
PfamiPF03483. B3_4. 1 hit.
PF03484. B5. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SMARTiSM00873. B3_4. 1 hit.
SM00874. B5. 1 hit.
[Graphical view]
SUPFAMiSSF46955. SSF46955. 2 hits.
SSF56037. SSF56037. 1 hit.
TIGRFAMsiTIGR00471. pheT_arch. 1 hit.
PROSITEiPS51483. B5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8U260-1 [UniParc]FASTAAdd to Basket

« Hide

MPKFDVAKSD LERLVGREFS VEEWEDLVLY AKCELDDVWE EDGKIYFKLD    50
SKDTNRPDLW SAEGVARQIR WALGLAKGLP KYEVEESDVV VYVDKKLRNI 100
RPYGVYAVVE GLKLDEEALS QLIQLQEKVA LTYGRRRREV AIGIFDFDKV 150
KPPIYYRAAE KTEKFVPLGY SEEMTLEEIL EKHEKGREYG HLIRDKPYYP 200
LLVDSEGNVL SMPPIINSEL TGRVTTETKN VFVDVTGWDL RKVMLALNVI 250
VTALAERGGK IKRVKVIYPD FEITTPDLTP KEFEVSFEYI RKLSGLELSN 300
EEIKELLERM MYEVEILSEN KAKVKYPAFR DDIMHTRDVL EDVLIAYGYN 350
NIDPEEPKLA VQGRGDPFKD FEDAIRDLMV GFGLQEVMTF NLTSKEVQFD 400
KMNIPEEEIV EIANPISSRW SALRKWLLPS LMEFLSNNTH EEYPQRIFEV 450
GLATLIDESR ETKTVSEPKL AVALAGSGYT FTNAKEILDS LMRHLGIEYD 500
IEETVHGSFI PGRVGKILVD GKEIGIIGEI HPQVLENWNI QVPVVAFEIF 550
LKPLYR 556
Length:556
Mass (Da):63,963
Last modified:June 1, 2002 - v1
Checksum:iCFFB32F60D001432
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009950 Genomic DNA. Translation: AAL81114.1.
RefSeqiNP_578719.1. NC_003413.1.
WP_011012127.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81114; AAL81114; PF0990.
GeneIDi1468855.
KEGGipfu:PF0990.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009950 Genomic DNA. Translation: AAL81114.1 .
RefSeqi NP_578719.1. NC_003413.1.
WP_011012127.1. NC_003413.1.

3D structure databases

ProteinModelPortali Q8U260.
SMRi Q8U260. Positions 2-349.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q8U260. 1 interaction.
STRINGi 186497.PF0990.

Proteomic databases

PRIDEi Q8U260.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL81114 ; AAL81114 ; PF0990 .
GeneIDi 1468855.
KEGGi pfu:PF0990.

Phylogenomic databases

eggNOGi COG0072.
HOGENOMi HOG000105094.
KOi K01890.
OMAi NTHRSYP.

Family and domain databases

Gene3Di 3.30.56.20. 1 hit.
HAMAPi MF_00284. Phe_tRNA_synth_beta2.
InterProi IPR005146. B3/B4_tRNA-bd.
IPR009061. DNA-bd_dom_put.
IPR004531. Phe-tRNA-synth_IIc_bsu_arc.
IPR020825. Phe-tRNA_synthase_B3/B4.
IPR022918. Phe_tRNA_ligase_beta2_bac/arc.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR005147. tRNA_synthase_B5-dom.
[Graphical view ]
Pfami PF03483. B3_4. 1 hit.
PF03484. B5. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view ]
SMARTi SM00873. B3_4. 1 hit.
SM00874. B5. 1 hit.
[Graphical view ]
SUPFAMi SSF46955. SSF46955. 2 hits.
SSF56037. SSF56037. 1 hit.
TIGRFAMsi TIGR00471. pheT_arch. 1 hit.
PROSITEi PS51483. B5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
    Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
    Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Entry informationi

Entry nameiSYFB_PYRFU
AccessioniPrimary (citable) accession number: Q8U260
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: June 1, 2002
Last modified: September 3, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi