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Protein

Phenylalanine--tRNA ligase beta subunit

Gene

pheT

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunitUniRule annotation (EC:6.1.1.20UniRule annotation)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunitUniRule annotation
Short name:
PheRSUniRule annotation
Gene namesi
Name:pheTUniRule annotation
Ordered Locus Names:PF0990
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001270081 – 556Phenylalanine--tRNA ligase beta subunitAdd BLAST556

Proteomic databases

PRIDEiQ8U260

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

IntActiQ8U260, 1 interactor
STRINGi186497.PF0990

Structurei

3D structure databases

ProteinModelPortaliQ8U260
SMRiQ8U260
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini278 – 354B5UniRule annotationAdd BLAST77

Sequence similaritiesi

Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00412 Archaea
COG0072 LUCA
HOGENOMiHOG000105094
KOiK01890
OMAiTFTLCSR
OrthoDBiPOG093Z01M4

Family and domain databases

Gene3Di3.50.40.10, 1 hit
HAMAPiMF_00284 Phe_tRNA_synth_beta2, 1 hit
InterProiView protein in InterPro
IPR005146 B3/B4_tRNA-bd
IPR009061 DNA-bd_dom_put_sf
IPR004531 Phe-tRNA-synth_IIc_bsu_arc
IPR020825 Phe-tRNA_synthase_B3/B4
IPR022918 Phe_tRNA_ligase_beta2_bac/arc
IPR002319 Phenylalanyl-tRNA_Synthase
IPR005147 tRNA_synthase_B5-dom
PfamiView protein in Pfam
PF03483 B3_4, 1 hit
PF03484 B5, 1 hit
PF01409 tRNA-synt_2d, 1 hit
SMARTiView protein in SMART
SM00873 B3_4, 1 hit
SM00874 B5, 1 hit
SUPFAMiSSF46955 SSF46955, 2 hits
TIGRFAMsiTIGR00471 pheT_arch, 1 hit
PROSITEiView protein in PROSITE
PS51483 B5, 1 hit

Sequencei

Sequence statusi: Complete.

Q8U260-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKFDVAKSD LERLVGREFS VEEWEDLVLY AKCELDDVWE EDGKIYFKLD
60 70 80 90 100
SKDTNRPDLW SAEGVARQIR WALGLAKGLP KYEVEESDVV VYVDKKLRNI
110 120 130 140 150
RPYGVYAVVE GLKLDEEALS QLIQLQEKVA LTYGRRRREV AIGIFDFDKV
160 170 180 190 200
KPPIYYRAAE KTEKFVPLGY SEEMTLEEIL EKHEKGREYG HLIRDKPYYP
210 220 230 240 250
LLVDSEGNVL SMPPIINSEL TGRVTTETKN VFVDVTGWDL RKVMLALNVI
260 270 280 290 300
VTALAERGGK IKRVKVIYPD FEITTPDLTP KEFEVSFEYI RKLSGLELSN
310 320 330 340 350
EEIKELLERM MYEVEILSEN KAKVKYPAFR DDIMHTRDVL EDVLIAYGYN
360 370 380 390 400
NIDPEEPKLA VQGRGDPFKD FEDAIRDLMV GFGLQEVMTF NLTSKEVQFD
410 420 430 440 450
KMNIPEEEIV EIANPISSRW SALRKWLLPS LMEFLSNNTH EEYPQRIFEV
460 470 480 490 500
GLATLIDESR ETKTVSEPKL AVALAGSGYT FTNAKEILDS LMRHLGIEYD
510 520 530 540 550
IEETVHGSFI PGRVGKILVD GKEIGIIGEI HPQVLENWNI QVPVVAFEIF

LKPLYR
Length:556
Mass (Da):63,963
Last modified:June 1, 2002 - v1
Checksum:iCFFB32F60D001432
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA Translation: AAL81114.1
RefSeqiWP_011012127.1, NC_003413.1

Genome annotation databases

EnsemblBacteriaiAAL81114; AAL81114; PF0990
GeneIDi1468855
KEGGipfu:PF0990
PATRICifig|186497.12.peg.1049

Entry informationi

Entry nameiSYFB_PYRFU
AccessioniPrimary (citable) accession number: Q8U260
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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