Q8U1S1 (KAD6_PYRFU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative adenylate kinase
EC=2.7.4.3

Alternative name(s):
ATP-AMP transphosphorylase

Gene names

Ordered Locus Names:

PF1134

Organism

Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)

Taxonomic identifier

186497 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00039
Sequence similarities	Belongs to the adenylate kinase family. AK6 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activity Inferred from electronic annotation. Source: EC shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Putative adenylate kinase HAMAP MF_00039		PRO_0000153912
Regions
	Nucleotide binding	7 – 14	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8U1S1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 17B9DABBBCE57454	FASTA	180	20,033
	10 20 30 40 50 60 MIIAITGTPG VGKTTVARKL AEKLGCKYVN LRDFALEKGI GEVKGDELEV EVDELAYFVE 70 80 90 100 110 120 KEFKGKNVVL DGHLSHLMPA DLVIVLRAHP KTIAERLKER GYSKDKIGEN VEAELVDVIL 130 140 150 160 170 180 IEALDEHENV IEVDTTGKTP EEVVNEILNL INSGIKRRVG IVDWTKVYEE IIPYLRLGGD

References

[1]

"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences." Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T. Genetics 152:1299-1305(1999) [PubMed: 10430560] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009950 Genomic DNA. Translation: AAL81258.1.
RefSeq	NP_578863.1. NC_003413.1.
3D structure databases
ProteinModelPortal	Q8U1S1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBPYRT00000004668; EBPYRP00000004529; EBPYRG00000004668.
GeneID	1469003.
GenomeReviews	Gene locus PF1134 in contig AE009950_GR.
KEGG	pfu:PF1134.
NMPDR	fig|186497.1.peg.1174.
Phylogenomic databases
GeneTree	EBGT00050000023306.
HOGENOM	HBG646389.
OMA	EILDVCL.
PhylomeDB	Q8U1S1.
ProtClustDB	PRK03839.
Family and domain databases
HAMAP	MF_00039. Put_adenyl_kinase. [Tree]
InterPro	IPR020618. Adenylate_kinase_putative. IPR000623. Shikimate_kinase. [Graphical view]
Pfam	PF01202. SKI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD6_PYRFU

Accession

Primary (citable) accession number: Q8U1S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2002
Last modified:	December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program