Reviewed, UniProtKB/Swiss-Prot Q8U1S1 (KAD6_PYRFU)

Names and origin

Protein names

Recommended name:
    Putative adenylate kinase
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase

Gene names

Ordered Locus Names:

PF1134

Organism

Pyrococcus furiosus [Complete proteome] [HAMAP]

Taxonomic identifier

2261 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00039
Sequence similarities	Belongs to the adenylate kinase family. AK6 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylate kinase activity Inferred from electronic annotation. Source: HAMAP shikimate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	Putative adenylate kinase HAMAP MF_00039		PRO_0000153912
Regions
	Nucleotide binding	7 – 14	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8U1S1-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 17B9DABBBCE57454	FASTA	180	20,033
	10 20 30 40 50 60 MIIAITGTPG VGKTTVARKL AEKLGCKYVN LRDFALEKGI GEVKGDELEV EVDELAYFVE 70 80 90 100 110 120 KEFKGKNVVL DGHLSHLMPA DLVIVLRAHP KTIAERLKER GYSKDKIGEN VEAELVDVIL 130 140 150 160 170 180 IEALDEHENV IEVDTTGKTP EEVVNEILNL INSGIKRRVG IVDWTKVYEE IIPYLRLGGD

References

[1]	"The complete sequence of the Pyrococcus furiosus genome." Weiss R.B., Dunn D.M., Robb F.T., Brown J.R. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE010223 Genomic DNA. Translation: AAL81258.1.
RefSeq	NP_578863.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1469003.
GenomeReviews	Gene locus PF1134 in contig AE009950_GR.
KEGG	pfu:PF1134.
NMPDR	fig|186497.1.peg.1174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8U1S1.
OMA	Q8U1S1. RVGIVDW.
Enzyme and pathway databases
BRENDA	2.7.4.3. 321.
Family and domain databases
HAMAP	MF_00039. [Tree]
InterPro	IPR000623. Shik_kinase. [Graphical view]
Pfam	PF01202. SKI. 1 hit. [Graphical view]
ProDom	PD000657. Adenylate_kin. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

KAD6_PYRFU

Accession

Primary (citable) accession number: Q8U1S1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2002
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)