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Protein

Ribosome biogenesis protein Nop10

Gene

nop10

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome biogenesis protein Nop10
Gene namesi
Name:nop10
Ordered Locus Names:PF1141
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6060Ribosome biogenesis protein Nop10PRO_0000149024Add
BLAST

Proteomic databases

PRIDEiQ8U1R4.

Interactioni

Protein-protein interaction databases

DIPiDIP-48527N.
STRINGi186497.PF1141.

Structurei

Secondary structure

1
60
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni9 – 113Combined sources
Beta strandi14 – 196Combined sources
Turni21 – 233Combined sources
Beta strandi28 – 314Combined sources
Helixi42 – 5312Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EY4X-ray2.11E/F1-55[»]
2HVYX-ray2.30C1-60[»]
2RFKX-ray2.87B3-55[»]
3HAXX-ray2.11C1-60[»]
3HAYX-ray4.99C1-60[»]
3HJWX-ray2.35B3-55[»]
3HJYX-ray3.65B3-55[»]
3LWOX-ray2.86B1-60[»]
3LWPX-ray2.50B1-60[»]
3LWQX-ray2.68B1-60[»]
3LWRX-ray2.20B1-60[»]
3LWVX-ray2.50B1-60[»]
3MQKX-ray2.80B4-55[»]
ProteinModelPortaliQ8U1R4.
SMRiQ8U1R4. Positions 3-55.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8U1R4.

Family & Domainsi

Sequence similaritiesi

Belongs to the NOP10 family.Curated

Phylogenomic databases

eggNOGiarCOG00906. Archaea.
COG2260. LUCA.
HOGENOMiHOG000224954.
KOiK11130.
OMAiFRIRKCP.

Family and domain databases

HAMAPiMF_00803. Nop10. 1 hit.
InterProiIPR007264. H/ACA_rnp_Nop10.
IPR023532. Nop10_arc-typ.
[Graphical view]
PANTHERiPTHR13305. PTHR13305. 1 hit.
PfamiPF04135. Nop10p. 1 hit.
[Graphical view]
SUPFAMiSSF144210. SSF144210. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8U1R4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFRIRKCPK CGRYTLKEVC PVCGEKTKVA HPPRFSPEDP YGEYRRRWKR
60
EVLGIGRKEK
Length:60
Mass (Da):7,224
Last modified:June 1, 2002 - v1
Checksum:iAD087B8BCAA7214B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81265.1.
RefSeqiWP_011012281.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81265; AAL81265; PF1141.
GeneIDi1469010.
KEGGipfu:PF1141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81265.1.
RefSeqiWP_011012281.1. NC_003413.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EY4X-ray2.11E/F1-55[»]
2HVYX-ray2.30C1-60[»]
2RFKX-ray2.87B3-55[»]
3HAXX-ray2.11C1-60[»]
3HAYX-ray4.99C1-60[»]
3HJWX-ray2.35B3-55[»]
3HJYX-ray3.65B3-55[»]
3LWOX-ray2.86B1-60[»]
3LWPX-ray2.50B1-60[»]
3LWQX-ray2.68B1-60[»]
3LWRX-ray2.20B1-60[»]
3LWVX-ray2.50B1-60[»]
3MQKX-ray2.80B4-55[»]
ProteinModelPortaliQ8U1R4.
SMRiQ8U1R4. Positions 3-55.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48527N.
STRINGi186497.PF1141.

Proteomic databases

PRIDEiQ8U1R4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL81265; AAL81265; PF1141.
GeneIDi1469010.
KEGGipfu:PF1141.

Phylogenomic databases

eggNOGiarCOG00906. Archaea.
COG2260. LUCA.
HOGENOMiHOG000224954.
KOiK11130.
OMAiFRIRKCP.

Miscellaneous databases

EvolutionaryTraceiQ8U1R4.

Family and domain databases

HAMAPiMF_00803. Nop10. 1 hit.
InterProiIPR007264. H/ACA_rnp_Nop10.
IPR023532. Nop10_arc-typ.
[Graphical view]
PANTHERiPTHR13305. PTHR13305. 1 hit.
PfamiPF04135. Nop10p. 1 hit.
[Graphical view]
SUPFAMiSSF144210. SSF144210. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNOP10_PYRFU
AccessioniPrimary (citable) accession number: Q8U1R4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: June 1, 2002
Last modified: February 17, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.