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Protein

Putative ribose 1,5-bisphosphate isomerase

Gene

PF1530

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the conversion of ribose 1,5-bisphosphate to ribulose 1,5-bisphosphate (RuBP), the CO2 acceptor and substrate for RubisCO.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.UniRule annotation

Cofactori

NAD+UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 54NADUniRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ribose 1,5-bisphosphate isomeraseUniRule annotation (EC:5.3.1.29UniRule annotation)
Alternative name(s):
Ribulose 1,5-bisphosphate synthaseUniRule annotation
Short name:
RuBP synthaseUniRule annotation
Gene namesi
Ordered Locus Names:PF1530
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001539521 – 252Putative ribose 1,5-bisphosphate isomeraseAdd BLAST252

Proteomic databases

PRIDEiQ8U0Q5.

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi186497.PF1530.

Structurei

3D structure databases

ProteinModelPortaliQ8U0Q5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THI4 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.
OMAiRMGPVFG.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8U0Q5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKDVVISRA IVESYFKDLL NNLELDVAIV GAGPSGMVAG YYLAKGGAKV
60 70 80 90 100
AIFEKKLSIG GGIWGGGMGF NKIVVQEEAK EILDEFDIRY EEFEKGYYVA
110 120 130 140 150
DAIEVATTIA SKTVKAGVKI FNMVEVEDLV VKDDRVSGIV INWTPVKMTG
160 170 180 190 200
LHVDPLTVEA KYVIDSTGHG AQVTQFLLKR GLIEKIPGEG AMWAEMGEKL
210 220 230 240 250
TVENTKEVFP GLYVTGMAAN AVSGAPRMGP IFGGMFLSGR KAAMEILQKL

GL
Length:252
Mass (Da):27,157
Last modified:June 1, 2002 - v1
Checksum:iB91920C50B46F3FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81654.1.
RefSeqiWP_011012677.1. NC_003413.1.

Genome annotation databases

EnsemblBacteriaiAAL81654; AAL81654; PF1530.
GeneIDi1469406.
KEGGipfu:PF1530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA. Translation: AAL81654.1.
RefSeqiWP_011012677.1. NC_003413.1.

3D structure databases

ProteinModelPortaliQ8U0Q5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF1530.

Proteomic databases

PRIDEiQ8U0Q5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL81654; AAL81654; PF1530.
GeneIDi1469406.
KEGGipfu:PF1530.

Phylogenomic databases

eggNOGiarCOG00574. Archaea.
COG1635. LUCA.
HOGENOMiHOG000106048.
KOiK03146.
OMAiRMGPVFG.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00304. Thi4. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR002922. Thi4_fam.
IPR022828. Thi4_putative.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR00292. TIGR00292. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRUBPS_PYRFU
AccessioniPrimary (citable) accession number: Q8U0Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: June 1, 2002
Last modified: January 20, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.