Unreviewed, UniProtKB/TrEMBL Q8U0Q0 (Q8U0Q0_PYRFU)

Names and origin

Protein names

Recommended name:
    Phosphorylase RuleBase RU000587V2
    EC=2.4.1.1

Gene names

Ordered Locus Names:

PF1535

Organism

Pyrococcus furiosus [Complete proteome] [HAMAP]

Taxonomic identifier

2261 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	839 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587V2
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587V2
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587V2
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179V0

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587V2
Molecular function	Glycosyltransferase RuleBase RU000587V2 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8U0Q0-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: ACBF6DE68AA62084	FASTA	839	97,705
	10 20 30 40 50 60 MVKVENSIKK KIEKKLPENL KKLAELAYNY WWSWDDKAMK LWQRIDEDHW REYKNPVKLL 70 80 90 100 110 120 LDVPESRLKE LSRDDTFLDL YELVIERFNS YLNPETTWFS TNYPKWDKPI VYLCMEYGIS 130 140 150 160 170 180 KSLPIYSGGL GILAGDHLKT ASDLGLPLIG IGLLYKHGYF KQEIDKNGRQ IEIFPEYNIS 190 200 210 220 230 240 EMPIRQVLNE DGSPLLIDVP MENRIVKARV FLVKVGRVDL YLLDTDVPEN NEEDRKICDY 250 260 270 280 290 300 LYNAEPDKRI KQEILLGIGG MRLLKALGIE PGVIHLNEGH PAFANFERIR WLMDEGLSFE 310 320 330 340 350 360 EALEVVRGTS VFTTHTPVPA GHDVFPADFV REKLAKFFEG LPAEKFLDLG RRFPGDSNFN 370 380 390 400 410 420 MTVLSIKTSN FVNGVSKLHA KITREMWADL WKGVPIDEIP IEGITNGVHT ATWVHESIAK 430 440 450 460 470 480 LYDIYLGKIW REHINLEGIW YAIERIPDEE LWEAHLKAKR EFIDLVRRKI MRRNERLGIE 490 500 510 520 530 540 EPLPDIDENA LIIGFARRFA TYKRAVLLFT DLERLKRIVN NPERPVYIVF GGKAHPRDEA 550 560 570 580 590 600 GKEFLRRVYE VSQMPEFKGK IILIENYDMG SARLFVSGVD VWLNTPRRPL EASGTSGMKA 610 620 630 640 650 660 GLNGVINLSV YDGWWVEGYN GRNGWVVGDT TTEPESEEDD YWDAMSLYDL LENVVIPMYY 670 680 690 700 710 720 ENREAWIRMM KESIKSIAPN FSTHRMLKEY ITKFYSKAIE LGIFLSRDDY RWAKEIAKWK 730 740 750 760 770 780 EKIAREWENV NIEDVKVNKH VIEAIVNLGD LTPEDVRLEI YYGLVDGEQG LINANTVELR 790 800 810 820 830 PVKALGNGKY IYKYEGRALE RLQEPCWMYK LRIYAHHPML PTKFLLGGYI KWKDIEKKE

References

[1]	"The complete sequence of the Pyrococcus furiosus genome." Weiss R.B., Dunn D.M., Robb F.T., Brown J.R. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE009950 Genomic DNA. Translation: AAL81659.1.
RefSeq	NP_579264.1.
3D structure databases
HSSP	HSSP built from PDB template 1YGP based on UniProtKB P06738.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Genome annotation databases
GeneID	1469411.
GenomeReviews	Gene locus PF1535 in contig AE009950_GR.
KEGG	pfu:PF1535.
NMPDR	fig|186497.1.peg.1582.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8U0Q0.
OMA	Q8U0Q0. RRAAPYK.
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02094. more_P_ylases. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8U0Q0_PYRFU

Accession

Primary (citable) accession number: Q8U0Q0

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)