ID   Q8TZY3_PYRFU            Unreviewed;       212 AA.
AC   Q8TZY3;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   RecName: Full=Segregation/condensation protein A {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=PF1842 {ECO:0000313|EMBL:AAL81966.1};
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497 {ECO:0000313|EMBL:AAL81966.1, ECO:0000313|Proteomes:UP000001013};
RN   [1] {ECO:0000313|EMBL:AAL81966.1, ECO:0000313|Proteomes:UP000001013}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1
RC   {ECO:0000313|Proteomes:UP000001013};
RX   PubMed=10430560;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
RN   [2] {ECO:0007829|PDB:4I99}
RP   X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 126-212.
RX   PubMed=23353789; DOI=10.1038/nsmb.2488;
RA   Burmann F., Shin H.C., Basquin J., Soh Y.M., Gimenez-Oya V., Kim Y.G.,
RA   Oh B.H., Gruber S.;
RT   "An asymmetric SMC-kleisin bridge in prokaryotic condensin.";
RL   Nat. Struct. Mol. Biol. 20:371-379(2013).
RN   [3] {ECO:0007829|PDB:5XNS}
RP   X-RAY CRYSTALLOGRAPHY (2.01 ANGSTROMS) OF 143-212.
RX   PubMed=28689660; DOI=10.1016/j.molcel.2017.06.010;
RA   Diebold-Durand M.L., Lee H., Ruiz Avila L.B., Noh H., Shin H.C., Im H.,
RA   Bock F.P., Burmann F., Durand A., Basfeld A., Ham S., Basquin J., Oh B.H.,
RA   Gruber S.;
RT   "Structure of Full-Length SMC and Rearrangements Required for Chromosome
RT   Organization.";
RL   Mol. Cell 67:334-347.e5(2017).
CC   -!- INTERACTION:
CC       Q8TZY3; Q8TZY2: smc; NbExp=3; IntAct=EBI-16033344, EBI-2505615;
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DR   EMBL; AE009950; AAL81966.1; -; Genomic_DNA.
DR   RefSeq; WP_011012982.1; NZ_CP023154.1.
DR   PDB; 4I99; X-ray; 2.30 A; C/D=126-212.
DR   PDB; 5XNS; X-ray; 2.01 A; C=143-212.
DR   PDBsum; 4I99; -.
DR   PDBsum; 5XNS; -.
DR   AlphaFoldDB; Q8TZY3; -.
DR   SMR; Q8TZY3; -.
DR   DIP; DIP-60232N; -.
DR   IntAct; Q8TZY3; 1.
DR   STRING; 186497.PF1842; -.
DR   PaxDb; 186497-PF1842; -.
DR   GeneID; 41713662; -.
DR   KEGG; pfu:PF1842; -.
DR   PATRIC; fig|186497.12.peg.1913; -.
DR   eggNOG; arCOG02610; Archaea.
DR   HOGENOM; CLU_070251_1_1_2; -.
DR   OrthoDB; 53244at2157; -.
DR   PhylomeDB; Q8TZY3; -.
DR   Proteomes; UP000001013; Chromosome.
DR   Gene3D; 6.10.250.2410; -; 1.
DR   Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR   InterPro; IPR003768; ScpA.
DR   InterPro; IPR023093; ScpA-like_C.
DR   PANTHER; PTHR33969; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   PANTHER; PTHR33969:SF2; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR   Pfam; PF02616; SMC_ScpA; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4I99, ECO:0007829|PDB:5XNS};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001013}.
FT   COILED          100..127
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   212 AA;  25120 MW;  9B6534E32E0D4BEC CRC64;
     MEIEVTPVDI LLQLVKMGKV DPWNIDIVDL TEKYIKMLRE MQELDLRISA RAILAAAILV
     RMKSEALLNE DSREQEEKEE ERIRVEVDPL VPPLRRVERY YTLDDLIDAL MEALEEAERR
     KPKKKKKVEI DEEIFVIDDF RVDIEKYVEE LYKVVKKIYE KTGTPIKFWD LVPDVEPKII
     ARTFLYLLFL ENMGRVEIIQ EEPFGEILVV PM
//