Reviewed, UniProtKB/Swiss-Prot Q8TZS0 (RNP3_PYRFU)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 3
      Short name=RNase P component 3
    EC=3.1.26.5

Gene names

Name:	rnp3
Ordered Locus Names:	PF1914

Organism

Pyrococcus furiosus [Complete proteome] [HAMAP]

Taxonomic identifier

2261 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Pyrococcus

Protein attributes

Sequence length	214 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP MF_00756
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00756
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential. HAMAP MF_00756
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 214	214	Ribonuclease P protein component 3 HAMAP MF_00756		PRO_0000140045

Sequences

	Sequence		Length	Mass (Da)
	Q8TZS0-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: A915506635C02CFB	FASTA	214	24,495
	10 20 30 40 50 60 MAGGRNGVKF VEMDIRSREA YELAEEWFDD VVFSYEIPPG VLDKERLKEI KKEYGNVAIT 70 80 90 100 110 120 LINPKPSLVK EAVQRFKQNY LIYVESSDLR VVRYSIERGV DAVISPWANR KDQGIDHVLA 130 140 150 160 170 180 RMMNKRGVAL GFSLRPLLHQ NPYERANALK FMRKAWTLVN KYKVPRFISS SAKGKFQVRG 190 200 210 VKELISLGIA IGMEEVQAKA SLSFYPLGIL ERLK

References

[1]	"The complete sequence of the Pyrococcus furiosus genome." Weiss R.B., Dunn D.M., Robb F.T., Brown J.R. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009950 Genomic DNA. Translation: AAL82038.1.
RefSeq	NP_579643.1.
3D structure databases
SMR	Q8TZS0. Positions 7-214.
ModBase	Search...
Genome annotation databases
GeneID	1469794.
GenomeReviews	Gene locus PF1914 in contig AE009950_GR.
KEGG	pfu:PF1914.
NMPDR	fig|186497.1.peg.1964.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645643.
OMA	YLIYVES.
Enzyme and pathway databases
BRENDA	3.1.26.5. 321.
Family and domain databases
HAMAP	MF_00756. RNase_P_3. [Tree]
InterPro	IPR016195. Pol/histidinol_Pase-like. IPR002738. RNase_P_p30. [Graphical view]
Pfam	PF01876. RNase_P_p30. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP3_PYRFU

Accession

Primary (citable) accession number: Q8TZS0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2002
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)