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Q8TZS0 (RNP3_PYRFU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 3

Short name=RNase P component 3
EC=3.1.26.5
Gene names
Name:rnp3
Ordered Locus Names:PF1914
OrganismPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) [Reference proteome] [HAMAP]
Taxonomic identifier186497 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756

Subunit structure

Consists of a catalytic RNA component and at least 4 protein subunits Potential.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Ribonuclease P protein component 3 HAMAP-Rule MF_00756
PRO_0000140045

Sequences

Sequence LengthMass (Da)Tools
Q8TZS0 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: A915506635C02CFB

FASTA21424,495
        10         20         30         40         50         60 
MAGGRNGVKF VEMDIRSREA YELAEEWFDD VVFSYEIPPG VLDKERLKEI KKEYGNVAIT 

        70         80         90        100        110        120 
LINPKPSLVK EAVQRFKQNY LIYVESSDLR VVRYSIERGV DAVISPWANR KDQGIDHVLA 

       130        140        150        160        170        180 
RMMNKRGVAL GFSLRPLLHQ NPYERANALK FMRKAWTLVN KYKVPRFISS SAKGKFQVRG 

       190        200        210 
VKELISLGIA IGMEEVQAKA SLSFYPLGIL ERLK 

« Hide

References

[1]"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences."
Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M., DiRuggiero J., Robb F.T.
Genetics 152:1299-1305(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43587 / DSM 3638 / JCM 8422 / Vc1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009950 Genomic DNA. Translation: AAL82038.1.
RefSeqNP_579643.1. NC_003413.1.

3D structure databases

ProteinModelPortalQ8TZS0.
SMRQ8TZS0. Positions 7-214.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ8TZS0. 1 interaction.
STRING186497.PF1914.

Proteomic databases

PRIDEQ8TZS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL82038; AAL82038; PF1914.
GeneID1469794.
KEGGpfu:PF1914.

Phylogenomic databases

eggNOGCOG1603.
HOGENOMHOG000073988.
KOK03539.
OMAWFDEVVF.
ProtClustDBPRK03892.

Family and domain databases

HAMAPMF_00756. RNase_P_3.
InterProIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PfamPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP3_PYRFU
AccessionPrimary (citable) accession number: Q8TZS0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families