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Protein
Submitted name:

ATP-dependent RNA helicase, putative

Gene

PF2015

Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi584CalciumCombined sources1
Metal bindingi594CalciumCombined sources1
Metal bindingi595Calcium; via carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseImported, Hydrolase
LigandATP-binding, CalciumCombined sources, Metal-bindingCombined sources, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent RNA helicase, putativeImported
Gene namesi
Ordered Locus Names:PF2015Imported
OrganismiPyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)Imported
Taxonomic identifieri186497 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000001013 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8TZH8

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-15532996,EBI-15532996

GO - Molecular functioni

  • identical protein binding Source: IntAct

Protein-protein interaction databases

DIPiDIP-48431N
STRINGi186497.PF2015

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1J22X-ray1.80A548-689[»]
1J23X-ray1.78A548-689[»]
1J24X-ray1.78A548-689[»]
1J25X-ray1.78A548-689[»]
1WP9X-ray2.90A/B/C/D/E/F2-495[»]
1X2IX-ray1.45A/B691-764[»]
ProteinModelPortaliQ8TZH8
SMRiQ8TZH8
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8TZH8

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 185Helicase ATP-bindingInterPro annotationAdd BLAST168
Domaini345 – 512Helicase C-terminalInterPro annotationAdd BLAST168

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili530 – 550Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiarCOG00872 Archaea
COG1111 LUCA
COG1948 LUCA
HOGENOMiHOG000223976
KOiK10896
OMAiFYEPVPS
OrthoDBiPOG093Z0BUN

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR006166 ERCC4_domain
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR027417 P-loop_NTPase
IPR011335 Restrct_endonuc-II-like
IPR010994 RuvA_2-like
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF02732 ERCC4, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00891 ERCC4, 1 hit
SM00490 HELICc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF47781 SSF47781, 1 hit
SSF52540 SSF52540, 2 hits
SSF52980 SSF52980, 1 hit
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q8TZH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLLRRDLIQ PRIYQEVIYA KCKETNCLIV LPTGLGKTLI AMMIAEYRLT
60 70 80 90 100
KYGGKVLMLA PTKPLVLQHA ESFRRLFNLP PEKIVALTGE KSPEERSKAW
110 120 130 140 150
ARAKVIVATP QTIENDLLAG RISLEDVSLI VFDEAHRAVG NYAYVFIARE
160 170 180 190 200
YKRQAKNPLV IGLTASPGST PEKIMEVINN LGIEHIEYRS ENSPDVRPYV
210 220 230 240 250
KGIRFEWVRV DLPEIYKEVR KLLREMLRDA LKPLAETGLL ESSSPDIPKK
260 270 280 290 300
EVLRAGQIIN EEMAKGNHDL RGLLLYHAMA LKLHHAIELL ETQGLSALRA
310 320 330 340 350
YIKKLYEEAK AGSTKASKEI FSDKRMKKAI SLLVQAKEIG LDHPKMDKLK
360 370 380 390 400
EIIREQLQRK QNSKIIVFTN YRETAKKIVN ELVKDGIKAK RFVGQASKEN
410 420 430 440 450
DRGLSQREQK LILDEFARGE FNVLVATSVG EEGLDVPEVD LVVFYEPVPS
460 470 480 490 500
AIRSIQRRGR TGRHMPGRVI ILMAKGTRDE AYYWSSRQKE KIMQETIAKV
510 520 530 540 550
SQAIKKQKQT SLVDFVREKE SEKTSLDKWL KKEKEEATEK EEKKVKAQEG
560 570 580 590 600
VKVVVDSREL RSEVVKRLKL LGVKLEVKTL DVGDYIISED VAIERKSAND
610 620 630 640 650
FIQSIIDGRL FDQVKRLKEA YSRPIMIVEG SLYGIRNVHP NAIRGAIAAV
660 670 680 690 700
TVDFGVPIIF SSTPEETAQY IFLIAKREQE EREKPVRIRS EKKALTLAER
710 720 730 740 750
QRLIVEGLPH VSATLARRLL KHFGSVERVF TASVAELMKV EGIGEKIAKE
760
IRRVITAPYI EDEE
Length:764
Mass (Da):86,939
Last modified:June 1, 2002 - v1
Checksum:i0561F58EB8E15679
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009950 Genomic DNA Translation: AAL82139.1

Genome annotation databases

EnsemblBacteriaiAAL82139; AAL82139; PF2015
KEGGipfu:PF2015
PATRICifig|186497.12.peg.2092

Similar proteinsi

Entry informationi

Entry nameiQ8TZH8_PYRFU
AccessioniPrimary (citable) accession number: Q8TZH8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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