ID   KADA_METKA              Reviewed;         191 AA.
AC   Q8TZB0;
DT   10-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   16-JUN-2009, entry version 33.
DE   RecName: Full=Adenylate kinase;
DE            Short=AK;
DE            EC=2.7.4.3;
DE   AltName: Full=ATP-AMP transphosphorylase;
GN   Name=adkA; OrderedLocusNames=MK0025;
OS   Methanopyrus kandleri.
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=2320;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   MEDLINE=21927647; PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L.,
RA   Natale D.A., Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O.,
RA   Malykh A.G., Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19
RT   and monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- CATALYTIC ACTIVITY: ATP + AMP = 2 ADP.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the archaeal adenylate kinase family.
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DR   EMBL; AE010303; AAM01242.1; -; Genomic_DNA.
DR   RefSeq; NP_613312.1; -.
DR   HSSP; P43411; 1KHT.
DR   GeneID; 1477328; -.
DR   GenomeReviews; AE009439_GR; MK0025.
DR   KEGG; mka:MK0025; -.
DR   NMPDR; fig|190192.1.peg.25; -.
DR   HOGENOM; Q8TZB0; -.
DR   OMA; Q8TZB0; HRDEMRK.
DR   BioCyc; MKAN190192:MK0025-MON; -.
DR   BRENDA; 2.7.4.3; 7577.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004017; F:adenylate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   HAMAP; MF_00234; -; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    191       Adenylate kinase.
FT                                /FTId=PRO_0000131815.
FT   NP_BIND       9     17       ATP (By similarity).
SQ   SEQUENCE   191 AA;  21692 MW;  3A34413D4073D1EA CRC64;
     MGYVIVATGV PGVGATTVTT EAVKELEGYE HVNYGDVMLE IAKEEGLVEH RDEIRKLPAE
     KQREIQRLAA RRIAKMAEEK EGIIVDTHCT IKTPAGYLPG LPIWVLEELQ PDVIVLIEAD
     PDEIMMRRVK DSEERQRDYD RAHEIEEHQK MNRMAAMAYA ALTGATVKII ENHDDRLEEA
     VREFVETVRS L
//