Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8TYV1

- CAPPA_METKA

UniProt

Q8TYV1 - CAPPA_METKA

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:MK0190
    OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
    Taxonomic identifieri190192 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
    ProteomesiUP000001826: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 532532Phosphoenolpyruvate carboxylasePRO_0000309601Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi190192.MK0190.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TYV1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1892.
    HOGENOMiHOG000009826.
    KOiK01595.
    OMAiDEYMPDY.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8TYV1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKVREARIA RTLATQHPDA TKFVRVQEEP EEAVECLVEL GAEEYMVDFE    50
    GKLTPYLQPI QVLMELYDAG VRVGEERFVI VRVPSATKEN VLRQVQALLG 100
    VMEANSELLK EDPDARGIFE VVHPMTSSPE ELVETVDRIS YARRFASREL 150
    DVPLKAGNLR IIPLIEEVPE LLDIRNILTG YVEGMREIGM DVSYLRVFIG 200
    RSDPALSYGH LPAVLACKLA IFEVYELSDE LGVPMAPILG GGCLPFRGHI 250
    RPGMEEEFVE EYAGTATYTV QSGFRYDHDR EKAVASIRRI NELAANDPLQ 300
    LSGDDIEYLV LATAIFMKHY LSVFFRCIGT LNIVADMIPN TRDRLARKGP 350
    VGYARDIPEP DRVGAQCKDL GDVGRELYRE LRRMRVEKLP ELPRAIKFTG 400
    ACYTVGMPPE LIGTGRGLAE IEERLGEDAL DAVISRLYPM LREDLQFAVE 450
    YTFLETAGSV LPSSGVAMVN TDLEYCVEYL DLEPPSDFEY QNLVHTLEPY 500
    LRYVVSEGGV EEVNPFVRDL LLEMGRMRGS LG 532
    Length:532
    Mass (Da):59,778
    Last modified:June 1, 2002 - v1
    Checksum:i98E64A0E55D089C9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM01407.1.
    RefSeqiNP_613477.1. NC_003551.1.
    WP_011018562.1. NC_003551.1.

    Genome annotation databases

    EnsemblBacteriaiAAM01407; AAM01407; MK0190.
    GeneIDi1477493.
    KEGGimka:MK0190.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM01407.1 .
    RefSeqi NP_613477.1. NC_003551.1.
    WP_011018562.1. NC_003551.1.

    3D structure databases

    ProteinModelPortali Q8TYV1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190192.MK0190.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM01407 ; AAM01407 ; MK0190 .
    GeneIDi 1477493.
    KEGGi mka:MK0190.

    Phylogenomic databases

    eggNOGi COG1892.
    HOGENOMi HOG000009826.
    KOi K01595.
    OMAi DEYMPDY.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

    Entry informationi

    Entry nameiCAPPA_METKA
    AccessioniPrimary (citable) accession number: Q8TYV1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3