Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8TYB6

- RNP2_METKA

UniProt

Q8TYB6 - RNP2_METKA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:MK0386
OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifieri190192 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
ProteomesiUP000001826: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 161161Ribonuclease P protein component 2PRO_0000140021Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi190192.MK0386.

Structurei

3D structure databases

ProteinModelPortaliQ8TYB6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1369.
KOiK03537.
OMAiINNDATQ.

Family and domain databases

HAMAPiMF_00755. RNase_P_2.
InterProiIPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFiPIRSF004952. RNase_P_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8TYB6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRVRLSSALR PRWRYVTFKV WSERVEALDF GGMKDLVVRA LLSVLGPTGT
60 70 80 90 100
GRIGPWLVRS YRDLNAGILR VRRGQEEEAR AALSLYRRDP KLGRVFIEVL
110 120 130 140 150
GTSGTIKGAE RYLSRIPKWD RERVGNREFV LYENGEVDVV EDGRIVAFAS
160
FECPLPEENR G
Length:161
Mass (Da):18,424
Last modified:April 13, 2004 - v2
Checksum:i9C319351A71DB9D5
GO

Sequence cautioni

The sequence AAM01601.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM01601.1. Different initiation.
RefSeqiNP_613671.1. NC_003551.1.

Genome annotation databases

EnsemblBacteriaiAAM01601; AAM01601; MK0386.
GeneIDi1477689.
KEGGimka:MK0386.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM01601.1 . Different initiation.
RefSeqi NP_613671.1. NC_003551.1.

3D structure databases

ProteinModelPortali Q8TYB6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190192.MK0386.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM01601 ; AAM01601 ; MK0386 .
GeneIDi 1477689.
KEGGi mka:MK0386.

Phylogenomic databases

eggNOGi COG1369.
KOi K03537.
OMAi INNDATQ.

Family and domain databases

HAMAPi MF_00755. RNase_P_2.
InterProi IPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view ]
Pfami PF01900. RNase_P_Rpp14. 1 hit.
[Graphical view ]
PIRSFi PIRSF004952. RNase_P_2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Entry informationi

Entry nameiRNP2_METKA
AccessioniPrimary (citable) accession number: Q8TYB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: October 29, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3