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Q8TYB6

- RNP2_METKA

UniProt

Q8TYB6 - RNP2_METKA

Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 2 (13 Apr 2004)
      Previous versions | rss
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    Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 2UniRule annotation
    Alternative name(s):
    Pop5UniRule annotation
    Gene namesi
    Name:rnp2UniRule annotation
    Ordered Locus Names:MK0386
    OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
    Taxonomic identifieri190192 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
    ProteomesiUP000001826: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 161161Ribonuclease P protein component 2PRO_0000140021Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi190192.MK0386.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TYB6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1369.
    KOiK03537.
    OMAiINNDATQ.

    Family and domain databases

    HAMAPiMF_00755. RNase_P_2.
    InterProiIPR002759. RNase_P/MRP_subunit.
    IPR016434. RNase_P_comp-2.
    [Graphical view]
    PfamiPF01900. RNase_P_Rpp14. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004952. RNase_P_2. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8TYB6-1 [UniParc]FASTAAdd to Basket

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    MRVRLSSALR PRWRYVTFKV WSERVEALDF GGMKDLVVRA LLSVLGPTGT    50
    GRIGPWLVRS YRDLNAGILR VRRGQEEEAR AALSLYRRDP KLGRVFIEVL 100
    GTSGTIKGAE RYLSRIPKWD RERVGNREFV LYENGEVDVV EDGRIVAFAS 150
    FECPLPEENR G 161
    Length:161
    Mass (Da):18,424
    Last modified:April 13, 2004 - v2
    Checksum:i9C319351A71DB9D5
    GO

    Sequence cautioni

    The sequence AAM01601.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM01601.1. Different initiation.
    RefSeqiNP_613671.1. NC_003551.1.

    Genome annotation databases

    EnsemblBacteriaiAAM01601; AAM01601; MK0386.
    GeneIDi1477689.
    KEGGimka:MK0386.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM01601.1 . Different initiation.
    RefSeqi NP_613671.1. NC_003551.1.

    3D structure databases

    ProteinModelPortali Q8TYB6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190192.MK0386.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM01601 ; AAM01601 ; MK0386 .
    GeneIDi 1477689.
    KEGGi mka:MK0386.

    Phylogenomic databases

    eggNOGi COG1369.
    KOi K03537.
    OMAi INNDATQ.

    Family and domain databases

    HAMAPi MF_00755. RNase_P_2.
    InterProi IPR002759. RNase_P/MRP_subunit.
    IPR016434. RNase_P_comp-2.
    [Graphical view ]
    Pfami PF01900. RNase_P_Rpp14. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004952. RNase_P_2. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

    Entry informationi

    Entry nameiRNP2_METKA
    AccessioniPrimary (citable) accession number: Q8TYB6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 13, 2004
    Last sequence update: April 13, 2004
    Last modified: October 1, 2014
    This is version 50 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3