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Q8TXZ9

- TRPF_METKA

UniProt

Q8TXZ9 - TRPF_METKA

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, MK0508
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:MK0508
OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifieri190192 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
ProteomesiUP000001826: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 216216N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_0000154404Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi190192.MK0508.

Structurei

3D structure databases

ProteinModelPortaliQ8TXZ9.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiETHDWER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8TXZ9-1 [UniParc]FASTAAdd to Basket

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MVRVKICGIT RPEDAATADE AGTDAVGCVV EVPVSTPRKV SAEHANEVFS    50
VVSPFVSRVA VLMDNLEPID RLEEATAVQL HGTEDPETCE ELSELGLDVI 100
KTFWVDQRGS VWLGEELIGD EVLAEYCEIV DAVLLDTKSA EGGGSGERHD 150
WDASARLVRR LDVPVILAGG LNPENVREAV EKVRPYAVDT SSGVEKEPGI 200
KDPEAIAEFV RATKSV 216
Length:216
Mass (Da):23,294
Last modified:June 1, 2002 - v1
Checksum:iDBAC90CDEAAE1DD8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM01723.1.
RefSeqiNP_613793.1. NC_003551.1.

Genome annotation databases

EnsemblBacteriaiAAM01723; AAM01723; MK0508.
GeneIDi1476609.
KEGGimka:MK0508.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM01723.1 .
RefSeqi NP_613793.1. NC_003551.1.

3D structure databases

ProteinModelPortali Q8TXZ9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190192.MK0508.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM01723 ; AAM01723 ; MK0508 .
GeneIDi 1476609.
KEGGi mka:MK0508.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi ETHDWER.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Entry informationi

Entry nameiTRPF_METKA
AccessioniPrimary (citable) accession number: Q8TXZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: June 1, 2002
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3