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Protein

Nascent polypeptide-associated complex protein

Gene

nac

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Contacts the emerging nascent chain on the ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nascent polypeptide-associated complex proteinUniRule annotation
Gene namesi
Name:nacUniRule annotation
Synonyms:egd2
Ordered Locus Names:MK0955
OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifieri190192 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
Proteomesi
  • UP000001826 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001356031 – 116Nascent polypeptide-associated complex proteinAdd BLAST116

Interactioni

Subunit structurei

Homodimer. Interacts with the ribosome. Binds ribosomal RNA.UniRule annotation

Protein-protein interaction databases

STRINGi190192.MK0955.

Structurei

3D structure databases

ProteinModelPortaliQ8TWS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 75NAC-A/BUniRule annotationAdd BLAST70
Domaini76 – 114UBAUniRule annotationAdd BLAST39

Sequence similaritiesi

Belongs to the NAC-alpha family.UniRule annotation
Contains 1 NAC-A/B (NAC-alpha/beta) domain.UniRule annotation
Contains 1 UBA domain.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Family and domain databases

HAMAPiMF_00814. NAC_arch. 1 hit.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8TWS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPGGKIDPR KLQRLMREMG MEQEPISGVE RVEIHLKDGS KLVFEKPQVI
60 70 80 90 100
RMKIMNQEFY QVAGKAKREK PEEEPFTDED VKLVAEQAGV SEEEARKALE
110
ETGGDLAEAI MRLQGE
Length:116
Mass (Da):13,216
Last modified:June 1, 2002 - v1
Checksum:iA836CB4E0134E046
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009439 Genomic DNA. Translation: AAM02168.1.

Genome annotation databases

EnsemblBacteriaiAAM02168; AAM02168; MK0955.
KEGGimka:MK0955.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009439 Genomic DNA. Translation: AAM02168.1.

3D structure databases

ProteinModelPortaliQ8TWS7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi190192.MK0955.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM02168; AAM02168; MK0955.
KEGGimka:MK0955.

Phylogenomic databases

eggNOGiarCOG04061. Archaea.
COG1308. LUCA.
HOGENOMiHOG000225886.
KOiK03626.
OMAiPRKMKQM.

Family and domain databases

HAMAPiMF_00814. NAC_arch. 1 hit.
InterProiIPR005231. NAC_arc.
IPR002715. Nas_poly-pep-assoc_cplx_dom.
IPR009060. UBA-like.
[Graphical view]
PfamiPF01849. NAC. 1 hit.
[Graphical view]
SMARTiSM01407. NAC. 1 hit.
[Graphical view]
SUPFAMiSSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00264. TIGR00264. 1 hit.
PROSITEiPS51151. NAC_AB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNAC_METKA
AccessioniPrimary (citable) accession number: Q8TWS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: June 1, 2002
Last modified: May 11, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.