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Q8TW42 (Q8TW42_METKA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338
Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338
Gene names
Name:purE EMBL AAM02408.1
Ordered Locus Names:MK1195
OrganismMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifier190192 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanopyri › Methanopyrales › Methanopyraceae › Methanopyrus

Protein attributes

Sequence length161 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338

Catalytic activity

5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338

Sequence similarities

Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Sequences

Sequence LengthMass (Da)Tools
Q8TW42 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: F26FA8DEBE19A461

FASTA16117,613
        10         20         30         40         50         60 
MVDVLIVLGS RSDRDVAEKA AKVLDRAGVD YNVRVASAHR TPERIDELIE EYEPDVKVYI 

        70         80         90        100        110        120 
AIAGLAAHLP GVIAAKTLKP VIAVPVEAKL CGLDALLSTV QMPPGVPVAV VGVDRGENAA 

       130        140        150        160 
LLALQILALE DEDVRSFLEE YREEMKKQVA RDDDTIKERF R

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE009439 Genomic DNA. Translation: AAM02408.1.
RefSeqNP_614478.1. NC_003551.1.

3D structure databases

HSSPHSSP built from PDB template 1QCZ based on UniProtKB P09028.
ProteinModelPortalQ8TW42.
SMRQ8TW42. Positions 4-161.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1477296.
GenomeReviewsGene locus MK1195 in contig AE009439_GR.
KEGGmka:MK1195.
NMPDRfig|190192.1.peg.1191.

Phylogenomic databases

HOGENOMHBG301965.
OMALIMGSDS.
PhylomeDBQ8TW42.

Family and domain databases

InterProIPR024694. N5-CAIR_mutase_PurE.
IPR000031. N5-CAIR_Mutase_PurE_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.7700. AIR_carboxyl. 1 hit.
KOK01588.
PfamPF00731. AIRC. 1 hit.
[Graphical view]
PIRSFPIRSF001338. AIR_carboxylase. 1 hit.
SMARTSM01001. AIRC. 1 hit.
[Graphical view]
SUPFAMSSF52255. AIR_carboxyl. 1 hit.
TIGRFAMsTIGR01162. PurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8TW42_METKA
AccessionPrimary (citable) accession number: Q8TW42
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info