ID   VATB_METKA              Reviewed;         990 AA.
AC   Q8TUT0;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 119.
DE   RecName: Full=V-type ATP synthase beta chain;
DE   AltName: Full=V-ATPase subunit B;
DE   Contains:
DE     RecName: Full=Mka AtpB intein;
GN   Name=atpB; OrderedLocusNames=MK1673;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanomada group; Methanopyri; Methanopyrales;
OC   Methanopyraceae; Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- FUNCTION: Produces ATP from ADP in the presence of a proton gradient
CC       across the membrane. The archaeal beta chain is a regulatory subunit.
CC   -!- PTM: This protein undergoes a protein self splicing that involves a
CC       post-translational excision of the VDE intervening region (intein)
CC       followed by peptide ligation. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family.
CC       {ECO:0000305}.
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DR   EMBL; AE009439; AAM02886.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TUT0; -.
DR   STRING; 190192.MK1673; -.
DR   PaxDb; 190192-MK1673; -.
DR   EnsemblBacteria; AAM02886; AAM02886; MK1673.
DR   KEGG; mka:MK1673; -.
DR   PATRIC; fig|190192.8.peg.1837; -.
DR   HOGENOM; CLU_301612_0_0_2; -.
DR   InParanoid; Q8TUT0; -.
DR   OrthoDB; 32941at2157; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR   GO; GO:0042777; P:proton motive force-driven plasma membrane ATP synthesis; IEA:UniProtKB-UniRule.
DR   CDD; cd18112; ATP-synt_V_A-type_beta_C; 1.
DR   CDD; cd18118; ATP-synt_V_A-type_beta_N; 1.
DR   CDD; cd00081; Hint; 1.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd01135; V_A-ATPase_B; 1.
DR   Gene3D; 3.40.50.12240; -; 2.
DR   Gene3D; 2.170.16.10; Hedgehog/Intein (Hint) domain; 1.
DR   Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR   HAMAP; MF_00310; ATP_synth_B_arch; 1.
DR   InterPro; IPR020003; ATPase_a/bsu_AS.
DR   InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR   InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR003586; Hint_dom_C.
DR   InterPro; IPR003587; Hint_dom_N.
DR   InterPro; IPR036844; Hint_dom_sf.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR006142; INTEIN.
DR   InterPro; IPR030934; Intein_C.
DR   InterPro; IPR004042; Intein_endonuc.
DR   InterPro; IPR006141; Intein_N.
DR   InterPro; IPR004860; LAGLIDADG_2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022879; V-ATPase_su_B/beta.
DR   NCBIfam; TIGR01443; intein_Cterm; 1.
DR   NCBIfam; TIGR01445; intein_Nterm; 1.
DR   PANTHER; PTHR43389; V-TYPE PROTON ATPASE SUBUNIT B; 1.
DR   PANTHER; PTHR43389:SF4; V-TYPE PROTON ATPASE SUBUNIT B; 1.
DR   Pfam; PF00006; ATP-synt_ab; 2.
DR   Pfam; PF02874; ATP-synt_ab_N; 1.
DR   Pfam; PF14890; Intein_splicing; 1.
DR   Pfam; PF14528; LAGLIDADG_3; 2.
DR   PRINTS; PR00379; INTEIN.
DR   SMART; SM00305; HintC; 1.
DR   SMART; SM00306; HintN; 1.
DR   SUPFAM; SSF47917; C-terminal domain of alpha and beta subunits of F1 ATP synthase; 1.
DR   SUPFAM; SSF51294; Hedgehog/intein (Hint) domain; 1.
DR   SUPFAM; SSF55608; Homing endonucleases; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
DR   PROSITE; PS50818; INTEIN_C_TER; 1.
DR   PROSITE; PS50819; INTEIN_ENDONUCLEASE; 1.
DR   PROSITE; PS50817; INTEIN_N_TER; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; Autocatalytic cleavage; DNA-binding; Endonuclease;
KW   Hydrogen ion transport; Hydrolase; Intron homing; Ion transport; Nuclease;
KW   Protein splicing; Reference proteome; Transport.
FT   CHAIN           1..260
FT                   /note="V-type ATP synthase beta chain, 1st part"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000002476"
FT   CHAIN           261..777
FT                   /note="Mka AtpB intein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000002477"
FT   CHAIN           778..990
FT                   /note="V-type ATP synthase beta chain, 2nd part"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000002478"
FT   DOMAIN          491..614
FT                   /note="DOD-type homing endonuclease"
SQ   SEQUENCE   990 AA;  110354 MW;  7AC6BE8A32B31585 CRC64;
     MAEAERPAGK EYTTISEVSG PLMVVEGVEG AKYGEVVEVE TPTGEVRRGQ VLEARRDAAV
     VQVFEGTSGL DTTSTKVRFT GETLRIPVST DLLGRILNGR GEPIDGGPEI VPEDELDIHG
     APINPAARKY PSDFIQTGIS AIDGMNTLVR GQKLPIFSGS GLPHNELAAQ IARQATVPGE
     EEEFAVVFAA MGITHEEAAF FRREFEETGA LDRAVLILNL ADDPSMERII TPRIALTVAE
     YLAFENDMHV LVILTDMTNY CFAPGTRVIT ASGDVVEIDE IVERAAETAV DGGLREGSTE
     VTVGVTNVRT LAAWDGDLTS NDVVAVEKIE APSRAVRVRT RSGAELVVSE DHKFLVDTED
     GPRMVEASEL KSGDELYSVR ELRVSEKVPT YLELLLEAED KFYVHPTEEF EEAVAERYGS
     LAEACREKEL PYRAREAKER RYYELSEFAR LATAVIESVD EATEYIDYVT AGGRKRVKFS
     SPRPGKEVMY VAGLIASDGS VDTERGFVMF SNTERELLSA FEEIVTEEFG VDASKTENQN
     GVTMLRVNSR VLARVFERLA DPKTVLKMPR ELVAAYLAGY VDGDGHLKDG KIVITTADRE
     RAGDLQLLLK RLGVPSVLRE RDGAYDVVVT GHDAAELAEE LPLRHPKKAE AAASMSSGRR
     SSRFDRVSRR FGRLLREVRR KYGVRASDLG SSSTISQIES GERRATRRLA LEIVERLEEV
     VGDVEEVREL RELAEGNYVL DEVVEVETVE YEHEYLYDVT VVPDHTLVVE NGIITSNCEA
     LREISAAREE VPGRRGYPGY MYTDLATIYE RAGCIRGRKG SITQMPILTM PHDDITHPIP
     DLTGYITEGQ IVLSRDLHRR GIYPPIDVLP SLSRLMDEGI GKGKTREDHP DLSNQLYAAY
     AEGRDLRDLV AVVGEEALTE RDRKFLKFAD EFEQRFVKQG RDENRSIEET LDLGWELLAI
     LPERELKRVS DELIEKYHPK YRQKKEEQEE
//