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Q8TUT0 (VATB_METKA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
V-type ATP synthase beta chain
Alternative name(s):
V-ATPase subunit B

Cleaved into the following chain:

  1. Mka AtpB intein
Gene names
Name:atpB
Ordered Locus Names:MK1673
OrganismMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) [Reference proteome] [HAMAP]
Taxonomic identifier190192 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus

Protein attributes

Sequence length990 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. HAMAP-Rule MF_00310

Post-translational modification

This protein undergoes a protein self splicing that involves a post-translational excision of the VDE intervening region (intein) followed by peptide ligation Potential. HAMAP-Rule MF_00310

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Contains 1 DOD-type homing endonuclease domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 260260V-type ATP synthase beta chain, 1st part Potential
PRO_0000002476
Chain261 – 777517Mka AtpB intein Potential
PRO_0000002477
Chain778 – 990213V-type ATP synthase beta chain, 2nd part Potential
PRO_0000002478

Regions

Domain491 – 614124DOD-type homing endonuclease

Sequences

Sequence LengthMass (Da)Tools
Q8TUT0 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 7AC6BE8A32B31585

FASTA990110,354
        10         20         30         40         50         60 
MAEAERPAGK EYTTISEVSG PLMVVEGVEG AKYGEVVEVE TPTGEVRRGQ VLEARRDAAV 

        70         80         90        100        110        120 
VQVFEGTSGL DTTSTKVRFT GETLRIPVST DLLGRILNGR GEPIDGGPEI VPEDELDIHG 

       130        140        150        160        170        180 
APINPAARKY PSDFIQTGIS AIDGMNTLVR GQKLPIFSGS GLPHNELAAQ IARQATVPGE 

       190        200        210        220        230        240 
EEEFAVVFAA MGITHEEAAF FRREFEETGA LDRAVLILNL ADDPSMERII TPRIALTVAE 

       250        260        270        280        290        300 
YLAFENDMHV LVILTDMTNY CFAPGTRVIT ASGDVVEIDE IVERAAETAV DGGLREGSTE 

       310        320        330        340        350        360 
VTVGVTNVRT LAAWDGDLTS NDVVAVEKIE APSRAVRVRT RSGAELVVSE DHKFLVDTED 

       370        380        390        400        410        420 
GPRMVEASEL KSGDELYSVR ELRVSEKVPT YLELLLEAED KFYVHPTEEF EEAVAERYGS 

       430        440        450        460        470        480 
LAEACREKEL PYRAREAKER RYYELSEFAR LATAVIESVD EATEYIDYVT AGGRKRVKFS 

       490        500        510        520        530        540 
SPRPGKEVMY VAGLIASDGS VDTERGFVMF SNTERELLSA FEEIVTEEFG VDASKTENQN 

       550        560        570        580        590        600 
GVTMLRVNSR VLARVFERLA DPKTVLKMPR ELVAAYLAGY VDGDGHLKDG KIVITTADRE 

       610        620        630        640        650        660 
RAGDLQLLLK RLGVPSVLRE RDGAYDVVVT GHDAAELAEE LPLRHPKKAE AAASMSSGRR 

       670        680        690        700        710        720 
SSRFDRVSRR FGRLLREVRR KYGVRASDLG SSSTISQIES GERRATRRLA LEIVERLEEV 

       730        740        750        760        770        780 
VGDVEEVREL RELAEGNYVL DEVVEVETVE YEHEYLYDVT VVPDHTLVVE NGIITSNCEA 

       790        800        810        820        830        840 
LREISAAREE VPGRRGYPGY MYTDLATIYE RAGCIRGRKG SITQMPILTM PHDDITHPIP 

       850        860        870        880        890        900 
DLTGYITEGQ IVLSRDLHRR GIYPPIDVLP SLSRLMDEGI GKGKTREDHP DLSNQLYAAY 

       910        920        930        940        950        960 
AEGRDLRDLV AVVGEEALTE RDRKFLKFAD EFEQRFVKQG RDENRSIEET LDLGWELLAI 

       970        980        990 
LPERELKRVS DELIEKYHPK YRQKKEEQEE 

« Hide

References

[1]"The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens."
Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N., Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A., Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G., Koonin E.V., Kozyavkin S.A.
Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE009439 Genomic DNA. Translation: AAM02886.1.
RefSeqNP_614956.1. NC_003551.1.

3D structure databases

ProteinModelPortalQ8TUT0.
SMRQ8TUT0. Positions 20-263, 765-981.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190192.MK1673.

Proteomic databases

PRIDEQ8TUT0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM02886; AAM02886; MK1673.
GeneID1478268.
KEGGmka:MK1673.

Phylogenomic databases

eggNOGCOG1372.
KOK02118.

Family and domain databases

Gene3D1.10.1140.10. 1 hit.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
HAMAPMF_00310. ATP_synth_B_arch.
InterProIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamPF00006. ATP-synt_ab. 2 hits.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
PF14528. LAGLIDADG_3. 2 hits.
[Graphical view]
PRINTSPR00379. INTEIN.
SMARTSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMSSF47917. SSF47917. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF55608. SSF55608. 2 hits.
TIGRFAMsTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVATB_METKA
AccessionPrimary (citable) accession number: Q8TUT0
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Intein-containing proteins

List of intein-containing protein entries