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Q8TUT0

- VATB_METKA

UniProt

Q8TUT0 - VATB_METKA

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Protein

V-type ATP synthase beta chain

Gene

atpB

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA binding Source: UniProtKB-KW
  3. endonuclease activity Source: UniProtKB-KW
  4. hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Source: InterPro

GO - Biological processi

  1. ATP biosynthetic process Source: UniProtKB-KW
  2. ATP hydrolysis coupled proton transport Source: InterPro
  3. intein-mediated protein splicing Source: InterPro
  4. intron homing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Intron homing, Ion transport, Transport

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATP synthase beta chain
Alternative name(s):
V-ATPase subunit B
Cleaved into the following chain:
Gene namesi
Name:atpB
Ordered Locus Names:MK1673
OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifieri190192 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
ProteomesiUP000001826: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. proton-transporting two-sector ATPase complex, catalytic domain Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260V-type ATP synthase beta chain, 1st partSequence AnalysisPRO_0000002476Add
BLAST
Chaini261 – 777517Mka AtpB inteinSequence AnalysisPRO_0000002477Add
BLAST
Chaini778 – 990213V-type ATP synthase beta chain, 2nd partSequence AnalysisPRO_0000002478Add
BLAST

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the VDE intervening region (intein) followed by peptide ligation.Curated

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Proteomic databases

PRIDEiQ8TUT0.

Interactioni

Protein-protein interaction databases

STRINGi190192.MK1673.

Structurei

3D structure databases

ProteinModelPortaliQ8TUT0.
SMRiQ8TUT0. Positions 20-263, 765-981.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini491 – 614124DOD-type homing endonucleaseAdd
BLAST

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.Curated

Phylogenomic databases

eggNOGiCOG1372.
KOiK02118.
OMAiVEYEHEY.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
2.170.16.10. 2 hits.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
HAMAPiMF_00310. ATP_synth_B_arch.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 2 hits.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
PF14528. LAGLIDADG_3. 2 hits.
[Graphical view]
PRINTSiPR00379. INTEIN.
SMARTiSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF55608. SSF55608. 2 hits.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TUT0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEAERPAGK EYTTISEVSG PLMVVEGVEG AKYGEVVEVE TPTGEVRRGQ
60 70 80 90 100
VLEARRDAAV VQVFEGTSGL DTTSTKVRFT GETLRIPVST DLLGRILNGR
110 120 130 140 150
GEPIDGGPEI VPEDELDIHG APINPAARKY PSDFIQTGIS AIDGMNTLVR
160 170 180 190 200
GQKLPIFSGS GLPHNELAAQ IARQATVPGE EEEFAVVFAA MGITHEEAAF
210 220 230 240 250
FRREFEETGA LDRAVLILNL ADDPSMERII TPRIALTVAE YLAFENDMHV
260 270 280 290 300
LVILTDMTNY CFAPGTRVIT ASGDVVEIDE IVERAAETAV DGGLREGSTE
310 320 330 340 350
VTVGVTNVRT LAAWDGDLTS NDVVAVEKIE APSRAVRVRT RSGAELVVSE
360 370 380 390 400
DHKFLVDTED GPRMVEASEL KSGDELYSVR ELRVSEKVPT YLELLLEAED
410 420 430 440 450
KFYVHPTEEF EEAVAERYGS LAEACREKEL PYRAREAKER RYYELSEFAR
460 470 480 490 500
LATAVIESVD EATEYIDYVT AGGRKRVKFS SPRPGKEVMY VAGLIASDGS
510 520 530 540 550
VDTERGFVMF SNTERELLSA FEEIVTEEFG VDASKTENQN GVTMLRVNSR
560 570 580 590 600
VLARVFERLA DPKTVLKMPR ELVAAYLAGY VDGDGHLKDG KIVITTADRE
610 620 630 640 650
RAGDLQLLLK RLGVPSVLRE RDGAYDVVVT GHDAAELAEE LPLRHPKKAE
660 670 680 690 700
AAASMSSGRR SSRFDRVSRR FGRLLREVRR KYGVRASDLG SSSTISQIES
710 720 730 740 750
GERRATRRLA LEIVERLEEV VGDVEEVREL RELAEGNYVL DEVVEVETVE
760 770 780 790 800
YEHEYLYDVT VVPDHTLVVE NGIITSNCEA LREISAAREE VPGRRGYPGY
810 820 830 840 850
MYTDLATIYE RAGCIRGRKG SITQMPILTM PHDDITHPIP DLTGYITEGQ
860 870 880 890 900
IVLSRDLHRR GIYPPIDVLP SLSRLMDEGI GKGKTREDHP DLSNQLYAAY
910 920 930 940 950
AEGRDLRDLV AVVGEEALTE RDRKFLKFAD EFEQRFVKQG RDENRSIEET
960 970 980 990
LDLGWELLAI LPERELKRVS DELIEKYHPK YRQKKEEQEE
Length:990
Mass (Da):110,354
Last modified:June 1, 2002 - v1
Checksum:i7AC6BE8A32B31585
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009439 Genomic DNA. Translation: AAM02886.1.
RefSeqiNP_614956.1. NC_003551.1.

Genome annotation databases

EnsemblBacteriaiAAM02886; AAM02886; MK1673.
GeneIDi1478268.
KEGGimka:MK1673.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009439 Genomic DNA. Translation: AAM02886.1 .
RefSeqi NP_614956.1. NC_003551.1.

3D structure databases

ProteinModelPortali Q8TUT0.
SMRi Q8TUT0. Positions 20-263, 765-981.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190192.MK1673.

Proteomic databases

PRIDEi Q8TUT0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM02886 ; AAM02886 ; MK1673 .
GeneIDi 1478268.
KEGGi mka:MK1673.

Phylogenomic databases

eggNOGi COG1372.
KOi K02118.
OMAi VEYEHEY.

Family and domain databases

Gene3Di 1.10.1140.10. 1 hit.
2.170.16.10. 2 hits.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
HAMAPi MF_00310. ATP_synth_B_arch.
InterProi IPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view ]
Pfami PF00006. ATP-synt_ab. 2 hits.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
PF14528. LAGLIDADG_3. 2 hits.
[Graphical view ]
PRINTSi PR00379. INTEIN.
SMARTi SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view ]
SUPFAMi SSF47917. SSF47917. 1 hit.
SSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF55608. SSF55608. 2 hits.
TIGRFAMsi TIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEi PS00152. ATPASE_ALPHA_BETA. 1 hit.
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Entry informationi

Entry nameiVATB_METKA
AccessioniPrimary (citable) accession number: Q8TUT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2002
Last modified: November 26, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3