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Q8TUT0

- VATB_METKA

UniProt

Q8TUT0 - VATB_METKA

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Protein
V-type ATP synthase beta chain
Gene
atpB, MK1673
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA binding Source: UniProtKB-KW
  3. endonuclease activity Source: UniProtKB-KW
  4. hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Source: InterPro

GO - Biological processi

  1. ATP biosynthetic process Source: UniProtKB-KW
  2. ATP hydrolysis coupled proton transport Source: InterPro
  3. intein-mediated protein splicing Source: InterPro
  4. intron homing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

ATP synthesis, Hydrogen ion transport, Intron homing, Ion transport, Transport

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
V-type ATP synthase beta chain
Alternative name(s):
V-ATPase subunit B
Cleaved into the following chain:
Gene namesi
Name:atpB
Ordered Locus Names:MK1673
OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Taxonomic identifieri190192 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
ProteomesiUP000001826: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. proton-transporting two-sector ATPase complex, catalytic domain Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260V-type ATP synthase beta chain, 1st part Reviewed prediction
PRO_0000002476Add
BLAST
Chaini261 – 777517Mka AtpB intein Reviewed prediction
PRO_0000002477Add
BLAST
Chaini778 – 990213V-type ATP synthase beta chain, 2nd part Reviewed prediction
PRO_0000002478Add
BLAST

Post-translational modificationi

This protein undergoes a protein self splicing that involves a post-translational excision of the VDE intervening region (intein) followed by peptide ligation Reviewed prediction.UniRule annotation

Keywords - PTMi

Autocatalytic cleavage, Protein splicing

Proteomic databases

PRIDEiQ8TUT0.

Interactioni

Protein-protein interaction databases

STRINGi190192.MK1673.

Structurei

3D structure databases

ProteinModelPortaliQ8TUT0.
SMRiQ8TUT0. Positions 20-263, 765-981.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini491 – 614124DOD-type homing endonuclease
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1372.
KOiK02118.
OMAiVEYEHEY.

Family and domain databases

Gene3Di1.10.1140.10. 1 hit.
2.170.16.10. 2 hits.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
HAMAPiMF_00310. ATP_synth_B_arch.
InterProiIPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view]
PfamiPF00006. ATP-synt_ab. 2 hits.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
PF14528. LAGLIDADG_3. 2 hits.
[Graphical view]
PRINTSiPR00379. INTEIN.
SMARTiSM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view]
SUPFAMiSSF47917. SSF47917. 1 hit.
SSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF55608. SSF55608. 2 hits.
TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TUT0-1 [UniParc]FASTAAdd to Basket

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MAEAERPAGK EYTTISEVSG PLMVVEGVEG AKYGEVVEVE TPTGEVRRGQ    50
VLEARRDAAV VQVFEGTSGL DTTSTKVRFT GETLRIPVST DLLGRILNGR 100
GEPIDGGPEI VPEDELDIHG APINPAARKY PSDFIQTGIS AIDGMNTLVR 150
GQKLPIFSGS GLPHNELAAQ IARQATVPGE EEEFAVVFAA MGITHEEAAF 200
FRREFEETGA LDRAVLILNL ADDPSMERII TPRIALTVAE YLAFENDMHV 250
LVILTDMTNY CFAPGTRVIT ASGDVVEIDE IVERAAETAV DGGLREGSTE 300
VTVGVTNVRT LAAWDGDLTS NDVVAVEKIE APSRAVRVRT RSGAELVVSE 350
DHKFLVDTED GPRMVEASEL KSGDELYSVR ELRVSEKVPT YLELLLEAED 400
KFYVHPTEEF EEAVAERYGS LAEACREKEL PYRAREAKER RYYELSEFAR 450
LATAVIESVD EATEYIDYVT AGGRKRVKFS SPRPGKEVMY VAGLIASDGS 500
VDTERGFVMF SNTERELLSA FEEIVTEEFG VDASKTENQN GVTMLRVNSR 550
VLARVFERLA DPKTVLKMPR ELVAAYLAGY VDGDGHLKDG KIVITTADRE 600
RAGDLQLLLK RLGVPSVLRE RDGAYDVVVT GHDAAELAEE LPLRHPKKAE 650
AAASMSSGRR SSRFDRVSRR FGRLLREVRR KYGVRASDLG SSSTISQIES 700
GERRATRRLA LEIVERLEEV VGDVEEVREL RELAEGNYVL DEVVEVETVE 750
YEHEYLYDVT VVPDHTLVVE NGIITSNCEA LREISAAREE VPGRRGYPGY 800
MYTDLATIYE RAGCIRGRKG SITQMPILTM PHDDITHPIP DLTGYITEGQ 850
IVLSRDLHRR GIYPPIDVLP SLSRLMDEGI GKGKTREDHP DLSNQLYAAY 900
AEGRDLRDLV AVVGEEALTE RDRKFLKFAD EFEQRFVKQG RDENRSIEET 950
LDLGWELLAI LPERELKRVS DELIEKYHPK YRQKKEEQEE 990
Length:990
Mass (Da):110,354
Last modified:June 1, 2002 - v1
Checksum:i7AC6BE8A32B31585
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM02886.1.
RefSeqiNP_614956.1. NC_003551.1.
WP_011020041.1. NC_003551.1.

Genome annotation databases

EnsemblBacteriaiAAM02886; AAM02886; MK1673.
GeneIDi1478268.
KEGGimka:MK1673.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009439 Genomic DNA. Translation: AAM02886.1 .
RefSeqi NP_614956.1. NC_003551.1.
WP_011020041.1. NC_003551.1.

3D structure databases

ProteinModelPortali Q8TUT0.
SMRi Q8TUT0. Positions 20-263, 765-981.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 190192.MK1673.

Proteomic databases

PRIDEi Q8TUT0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM02886 ; AAM02886 ; MK1673 .
GeneIDi 1478268.
KEGGi mka:MK1673.

Phylogenomic databases

eggNOGi COG1372.
KOi K02118.
OMAi VEYEHEY.

Family and domain databases

Gene3Di 1.10.1140.10. 1 hit.
2.170.16.10. 2 hits.
3.10.28.10. 2 hits.
3.40.50.300. 2 hits.
HAMAPi MF_00310. ATP_synth_B_arch.
InterProi IPR020003. ATPase_a/bsu_AS.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR004100. ATPase_F1_a/bsu_N.
IPR024034. ATPase_F1_bsu/V1_C.
IPR028992. Hedgehog/Intein_dom.
IPR003586. Hint_dom_C.
IPR003587. Hint_dom_N.
IPR027434. Homing_endonucl.
IPR006142. INTEIN.
IPR004042. Intein_endonuc.
IPR006141. Intein_splice_site.
IPR027417. P-loop_NTPase.
IPR022879. V-ATPase_su_B/beta.
[Graphical view ]
Pfami PF00006. ATP-synt_ab. 2 hits.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
PF14528. LAGLIDADG_3. 2 hits.
[Graphical view ]
PRINTSi PR00379. INTEIN.
SMARTi SM00305. HintC. 1 hit.
SM00306. HintN. 1 hit.
[Graphical view ]
SUPFAMi SSF47917. SSF47917. 1 hit.
SSF51294. SSF51294. 1 hit.
SSF52540. SSF52540. 2 hits.
SSF55608. SSF55608. 2 hits.
TIGRFAMsi TIGR01443. intein_Cterm. 1 hit.
TIGR01445. intein_Nterm. 1 hit.
PROSITEi PS00152. ATPASE_ALPHA_BETA. 1 hit.
PS50818. INTEIN_C_TER. 1 hit.
PS50819. INTEIN_ENDONUCLEASE. 1 hit.
PS50817. INTEIN_N_TER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Entry informationi

Entry nameiVATB_METKA
AccessioniPrimary (citable) accession number: Q8TUT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: June 1, 2002
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Intein-containing proteins
    List of intein-containing protein entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3