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Q8TUT0

- VATB_METKA

UniProt

Q8TUT0 - VATB_METKA

Protein

V-type ATP synthase beta chain

Gene

atpB

Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. DNA binding Source: UniProtKB-KW
    3. endonuclease activity Source: UniProtKB-KW
    4. hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances Source: InterPro

    GO - Biological processi

    1. ATP biosynthetic process Source: UniProtKB-KW
    2. ATP hydrolysis coupled proton transport Source: InterPro
    3. intein-mediated protein splicing Source: InterPro
    4. intron homing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    ATP synthesis, Hydrogen ion transport, Intron homing, Ion transport, Transport

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    V-type ATP synthase beta chain
    Alternative name(s):
    V-ATPase subunit B
    Cleaved into the following chain:
    Gene namesi
    Name:atpB
    Ordered Locus Names:MK1673
    OrganismiMethanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
    Taxonomic identifieri190192 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanopyriMethanopyralesMethanopyraceaeMethanopyrus
    ProteomesiUP000001826: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. proton-transporting two-sector ATPase complex, catalytic domain Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 260260V-type ATP synthase beta chain, 1st partSequence AnalysisPRO_0000002476Add
    BLAST
    Chaini261 – 777517Mka AtpB inteinSequence AnalysisPRO_0000002477Add
    BLAST
    Chaini778 – 990213V-type ATP synthase beta chain, 2nd partSequence AnalysisPRO_0000002478Add
    BLAST

    Post-translational modificationi

    This protein undergoes a protein self splicing that involves a post-translational excision of the VDE intervening region (intein) followed by peptide ligation.Curated

    Keywords - PTMi

    Autocatalytic cleavage, Protein splicing

    Proteomic databases

    PRIDEiQ8TUT0.

    Interactioni

    Protein-protein interaction databases

    STRINGi190192.MK1673.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TUT0.
    SMRiQ8TUT0. Positions 20-263, 765-981.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini491 – 614124DOD-type homing endonucleaseAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ATPase alpha/beta chains family.Curated

    Phylogenomic databases

    eggNOGiCOG1372.
    KOiK02118.
    OMAiVEYEHEY.

    Family and domain databases

    Gene3Di1.10.1140.10. 1 hit.
    2.170.16.10. 2 hits.
    3.10.28.10. 2 hits.
    3.40.50.300. 2 hits.
    HAMAPiMF_00310. ATP_synth_B_arch.
    InterProiIPR020003. ATPase_a/bsu_AS.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR024034. ATPase_F1_bsu/V1_C.
    IPR028992. Hedgehog/Intein_dom.
    IPR003586. Hint_dom_C.
    IPR003587. Hint_dom_N.
    IPR027434. Homing_endonucl.
    IPR006142. INTEIN.
    IPR004042. Intein_endonuc.
    IPR006141. Intein_splice_site.
    IPR027417. P-loop_NTPase.
    IPR022879. V-ATPase_su_B/beta.
    [Graphical view]
    PfamiPF00006. ATP-synt_ab. 2 hits.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    PF14528. LAGLIDADG_3. 2 hits.
    [Graphical view]
    PRINTSiPR00379. INTEIN.
    SMARTiSM00305. HintC. 1 hit.
    SM00306. HintN. 1 hit.
    [Graphical view]
    SUPFAMiSSF47917. SSF47917. 1 hit.
    SSF51294. SSF51294. 1 hit.
    SSF52540. SSF52540. 2 hits.
    SSF55608. SSF55608. 2 hits.
    TIGRFAMsiTIGR01443. intein_Cterm. 1 hit.
    TIGR01445. intein_Nterm. 1 hit.
    PROSITEiPS00152. ATPASE_ALPHA_BETA. 1 hit.
    PS50818. INTEIN_C_TER. 1 hit.
    PS50819. INTEIN_ENDONUCLEASE. 1 hit.
    PS50817. INTEIN_N_TER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8TUT0-1 [UniParc]FASTAAdd to Basket

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    MAEAERPAGK EYTTISEVSG PLMVVEGVEG AKYGEVVEVE TPTGEVRRGQ    50
    VLEARRDAAV VQVFEGTSGL DTTSTKVRFT GETLRIPVST DLLGRILNGR 100
    GEPIDGGPEI VPEDELDIHG APINPAARKY PSDFIQTGIS AIDGMNTLVR 150
    GQKLPIFSGS GLPHNELAAQ IARQATVPGE EEEFAVVFAA MGITHEEAAF 200
    FRREFEETGA LDRAVLILNL ADDPSMERII TPRIALTVAE YLAFENDMHV 250
    LVILTDMTNY CFAPGTRVIT ASGDVVEIDE IVERAAETAV DGGLREGSTE 300
    VTVGVTNVRT LAAWDGDLTS NDVVAVEKIE APSRAVRVRT RSGAELVVSE 350
    DHKFLVDTED GPRMVEASEL KSGDELYSVR ELRVSEKVPT YLELLLEAED 400
    KFYVHPTEEF EEAVAERYGS LAEACREKEL PYRAREAKER RYYELSEFAR 450
    LATAVIESVD EATEYIDYVT AGGRKRVKFS SPRPGKEVMY VAGLIASDGS 500
    VDTERGFVMF SNTERELLSA FEEIVTEEFG VDASKTENQN GVTMLRVNSR 550
    VLARVFERLA DPKTVLKMPR ELVAAYLAGY VDGDGHLKDG KIVITTADRE 600
    RAGDLQLLLK RLGVPSVLRE RDGAYDVVVT GHDAAELAEE LPLRHPKKAE 650
    AAASMSSGRR SSRFDRVSRR FGRLLREVRR KYGVRASDLG SSSTISQIES 700
    GERRATRRLA LEIVERLEEV VGDVEEVREL RELAEGNYVL DEVVEVETVE 750
    YEHEYLYDVT VVPDHTLVVE NGIITSNCEA LREISAAREE VPGRRGYPGY 800
    MYTDLATIYE RAGCIRGRKG SITQMPILTM PHDDITHPIP DLTGYITEGQ 850
    IVLSRDLHRR GIYPPIDVLP SLSRLMDEGI GKGKTREDHP DLSNQLYAAY 900
    AEGRDLRDLV AVVGEEALTE RDRKFLKFAD EFEQRFVKQG RDENRSIEET 950
    LDLGWELLAI LPERELKRVS DELIEKYHPK YRQKKEEQEE 990
    Length:990
    Mass (Da):110,354
    Last modified:June 1, 2002 - v1
    Checksum:i7AC6BE8A32B31585
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM02886.1.
    RefSeqiNP_614956.1. NC_003551.1.
    WP_011020041.1. NC_003551.1.

    Genome annotation databases

    EnsemblBacteriaiAAM02886; AAM02886; MK1673.
    GeneIDi1478268.
    KEGGimka:MK1673.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009439 Genomic DNA. Translation: AAM02886.1 .
    RefSeqi NP_614956.1. NC_003551.1.
    WP_011020041.1. NC_003551.1.

    3D structure databases

    ProteinModelPortali Q8TUT0.
    SMRi Q8TUT0. Positions 20-263, 765-981.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190192.MK1673.

    Proteomic databases

    PRIDEi Q8TUT0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM02886 ; AAM02886 ; MK1673 .
    GeneIDi 1478268.
    KEGGi mka:MK1673.

    Phylogenomic databases

    eggNOGi COG1372.
    KOi K02118.
    OMAi VEYEHEY.

    Family and domain databases

    Gene3Di 1.10.1140.10. 1 hit.
    2.170.16.10. 2 hits.
    3.10.28.10. 2 hits.
    3.40.50.300. 2 hits.
    HAMAPi MF_00310. ATP_synth_B_arch.
    InterProi IPR020003. ATPase_a/bsu_AS.
    IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR004100. ATPase_F1_a/bsu_N.
    IPR024034. ATPase_F1_bsu/V1_C.
    IPR028992. Hedgehog/Intein_dom.
    IPR003586. Hint_dom_C.
    IPR003587. Hint_dom_N.
    IPR027434. Homing_endonucl.
    IPR006142. INTEIN.
    IPR004042. Intein_endonuc.
    IPR006141. Intein_splice_site.
    IPR027417. P-loop_NTPase.
    IPR022879. V-ATPase_su_B/beta.
    [Graphical view ]
    Pfami PF00006. ATP-synt_ab. 2 hits.
    PF00306. ATP-synt_ab_C. 1 hit.
    PF02874. ATP-synt_ab_N. 1 hit.
    PF14528. LAGLIDADG_3. 2 hits.
    [Graphical view ]
    PRINTSi PR00379. INTEIN.
    SMARTi SM00305. HintC. 1 hit.
    SM00306. HintN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47917. SSF47917. 1 hit.
    SSF51294. SSF51294. 1 hit.
    SSF52540. SSF52540. 2 hits.
    SSF55608. SSF55608. 2 hits.
    TIGRFAMsi TIGR01443. intein_Cterm. 1 hit.
    TIGR01445. intein_Nterm. 1 hit.
    PROSITEi PS00152. ATPASE_ALPHA_BETA. 1 hit.
    PS50818. INTEIN_C_TER. 1 hit.
    PS50819. INTEIN_ENDONUCLEASE. 1 hit.
    PS50817. INTEIN_N_TER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

    Entry informationi

    Entry nameiVATB_METKA
    AccessioniPrimary (citable) accession number: Q8TUT0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Intein-containing proteins
      List of intein-containing protein entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3