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Q8TUF2 (PSD_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:MA_0115
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 171171Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029823
Chain172 – 20837Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029824

Sites

Site171 – 1722Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1721Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8TUF2 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: CAC6BCF94AEAB899

FASTA20823,399
        10         20         30         40         50         60 
MIAKGSEPWL FAAASATALF AILSWATDSL PFLNHAAHMG MALTFFMVIF FRDPERKVEI 

        70         80         90        100        110        120 
SDAYMISPAD GTVIDIRDRK ICIFMFLQNV HVNRAPISGK IREITYKKGG YLPAFCKDSE 

       130        140        150        160        170        180 
RNERNEFIIH SKYGDVEVTQ IAGTIARRIV TYSNVNDSVE QGQRIGMIRF GSRVDVTIPH 

       190        200 
DFDITVCKGE RVLAGKTVIA TIKNDRDF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE010299 Genomic DNA. Translation: AAM03569.1.
RefSeqNP_615089.1. NC_003552.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1472007.
GenomeReviewsGene locus MA_0115 in contig AE010299_GR.
KEGGmac:MA0115.
NMPDRfig|188937.1.peg.115.

Phylogenomic databases

HOGENOMHBG541103.
OMANERVVWH.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycMACE188937:MA0115-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_METAC
AccessionPrimary (citable) accession number: Q8TUF2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: June 1, 2002
Last modified: November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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