Q8TQ05 (Y1747_METAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ABC transporter ATP-binding protein MA_1747
EC=3.6.3.-

Gene names

Ordered Locus Names:

MA_1747

Organism

Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]

Taxonomic identifier

188937 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina › Methanosarcina acetivorans

Protein attributes

Sequence length	614 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system By similarity.
Subcellular location	Cell membrane; Peripheral membrane protein By similarity.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 614	614	Putative ABC transporter ATP-binding protein MA_1747		PRO_0000092138
Regions
	Domain	11 – 251	241	ABC transporter 1
	Domain	319 – 552	234	ABC transporter 2
	Nucleotide binding	45 – 52	8	ATP 1 Potential
	Nucleotide binding	352 – 359	8	ATP 2 Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8TQ05 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 1F85016152A6A872	FASTA	614	68,081
	10 20 30 40 50 60 MDPSKDTSPQ VRLEKITYNY PYSDAAALSD VNLELKKGEF VLLAGPSGCG KSTLVRCLNR 70 80 90 100 110 120 LVPEVSGGSF SGRVLLRGKD LTHEKVHSLA LEVGMVFQNP ETQLFSLTVA EDLAFGPENL 130 140 150 160 170 180 GLPGEEIRIR VKKVLKEVGL KGLEDHFIFT LSGGEKQRTA IGGNLAMQPE ILVLDEPTSD 190 200 210 220 230 240 LDPAGTGEVL ELLKHLNAEN RTTLILIEHK LDAVFEMVDR MLVMDEGRVI LDGKPFEILC 250 260 270 280 290 300 REEEKLRKLG IHPPQFTEIA RFLGFFSENS SIPAYETLLK RLTELLQASE VEIHPEDLEK 310 320 330 340 350 360 RESEIPAPAP QPRNTPPHVL IEQLCYRHED GSEAFEKLNL EIKRGEFLAL LGHNGAGKTT 370 380 390 400 410 420 LAGHLIGFYR PASGRILLDG KDISGYSTAR LSKQVGYLFQ NPDSQIFTNS VFEEVCFGLE 430 440 450 460 470 480 NLGMPEEKIK KLADSALEMM ELSAYRNRHP HALSRGQRQR LAVASILALE PDLLILDEPT 490 500 510 520 530 540 TGQDRGHIRK FLDKIRKLNG LGKTVILITH DMELAAEYAE RVVVMKQGKI FLDGPTAEVF 550 560 570 580 590 600 SSPEELGAAG LLPPLPARLA LDLRKLGIDI PRLLTVSDLK SFLKARCPEL SACRPTEIEK 610 IVEENDSGEE VSLF

References

[1]

"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity." Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P. , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B. Genome Res. 12:532-542(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010299 Genomic DNA. Translation: AAM05154.1.
RefSeq	NP_616674.1. NC_003552.1.
3D structure databases
ProteinModelPortal	Q8TQ05.
ModBase	Search...
Protein-protein interaction databases
STRING	188937.MA1747.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM05154; AAM05154; MA_1747.
GeneID	1473635.
KEGG	mac:MA1747.
Phylogenomic databases
eggNOG	COG1122.
KO	K16786. K16787.
OMA	ENVKDQH.
ProtClustDB	CLSK378874.
Enzyme and pathway databases
BioCyc	MACE188937:GI2O-1806-MONOMER.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. False negative. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1747_METAC

Accession

Primary (citable) accession number: Q8TQ05

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 21, 2004
Last sequence update:	June 1, 2002
Last modified:	May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program