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Q8TPX3

- RNP2_METAC

UniProt

Q8TPX3 - RNP2_METAC

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Protein
Ribonuclease P protein component 2
Gene
rnp2, rnpB, MA_1781
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciMACE188937:GI2O-1799-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2 (EC:3.1.26.5)
Short name:
RNase P component 2
Alternative name(s):
Pop5
Gene namesi
Name:rnp2
Synonyms:rnpB
Ordered Locus Names:MA_1781
OrganismiMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Taxonomic identifieri188937 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000002487: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 132132Ribonuclease P protein component 2UniRule annotation
PRO_0000140019Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits By similarity.

Protein-protein interaction databases

STRINGi188937.MA1781.

Structurei

3D structure databases

ProteinModelPortaliQ8TPX3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1369.
KOiK03537.
OMAiEVACESE.
PhylomeDBiQ8TPX3.

Family and domain databases

HAMAPiMF_00755. RNase_P_2.
InterProiIPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFiPIRSF004952. RNase_P_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8TPX3-1 [UniParc]FASTAAdd to Basket

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MKRLLPSLRT KKRYLAFELI SEEPAGRGDI VKEVISSASS LLGDITTSDC    50
DIRVLGFEAG KGIIQCSHTR VKETRAALAT LTRVNGKRAT LHVLGASGTV 100
KKATEKFLKD YTVFEPEIHE KRDSRKTPGK VD 132
Length:132
Mass (Da):14,556
Last modified:June 1, 2002 - v1
Checksum:iE74EC35B89A41D96
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010299 Genomic DNA. Translation: AAM05187.1.
RefSeqiNP_616707.1. NC_003552.1.
WP_011021784.1. NC_003552.1.

Genome annotation databases

EnsemblBacteriaiAAM05187; AAM05187; MA_1781.
GeneIDi1473670.
KEGGimac:MA1781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010299 Genomic DNA. Translation: AAM05187.1 .
RefSeqi NP_616707.1. NC_003552.1.
WP_011021784.1. NC_003552.1.

3D structure databases

ProteinModelPortali Q8TPX3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 188937.MA1781.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM05187 ; AAM05187 ; MA_1781 .
GeneIDi 1473670.
KEGGi mac:MA1781.

Phylogenomic databases

eggNOGi COG1369.
KOi K03537.
OMAi EVACESE.
PhylomeDBi Q8TPX3.

Enzyme and pathway databases

BioCyci MACE188937:GI2O-1799-MONOMER.

Family and domain databases

HAMAPi MF_00755. RNase_P_2.
InterProi IPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view ]
Pfami PF01900. RNase_P_Rpp14. 1 hit.
[Graphical view ]
PIRSFi PIRSF004952. RNase_P_2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity."
    Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.
    , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.
    Genome Res. 12:532-542(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

Entry informationi

Entry nameiRNP2_METAC
AccessioniPrimary (citable) accession number: Q8TPX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2002
Last modified: September 3, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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