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Q8TPX3 (RNP2_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 2

Short name=RNase P component 2
EC=3.1.26.5
Gene names
Name:rnp2
Synonyms:rnpB
Ordered Locus Names:MA_1781
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length132 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00755

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00755

Subunit structure

Consists of a catalytic RNA component and at least 4 protein subunits Potential.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 132132Ribonuclease P protein component 2 HAMAP-Rule MF_00755
PRO_0000140019

Sequences

Sequence LengthMass (Da)Tools
Q8TPX3 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: E74EC35B89A41D96

FASTA13214,556
        10         20         30         40         50         60 
MKRLLPSLRT KKRYLAFELI SEEPAGRGDI VKEVISSASS LLGDITTSDC DIRVLGFEAG 

        70         80         90        100        110        120 
KGIIQCSHTR VKETRAALAT LTRVNGKRAT LHVLGASGTV KKATEKFLKD YTVFEPEIHE 

       130 
KRDSRKTPGK VD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE010299 Genomic DNA. Translation: AAM05187.1.
RefSeqNP_616707.1. NC_003552.1.

3D structure databases

ProteinModelPortalQ8TPX3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING188937.MA1781.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM05187; AAM05187; MA_1781.
GeneID1473670.
KEGGmac:MA1781.

Phylogenomic databases

eggNOGCOG1369.
KOK03537.
OMAEVACESE.
PhylomeDBQ8TPX3.
ProtClustDBCLSK2558365.

Enzyme and pathway databases

BioCycMACE188937:GI2O-1799-MONOMER.

Family and domain databases

HAMAPMF_00755. RNase_P_2.
InterProIPR002759. RNase_P/MRP_subunit.
IPR016434. RNase_P_comp-2.
[Graphical view]
PfamPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
PIRSFPIRSF004952. RNase_P_2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP2_METAC
AccessionPrimary (citable) accession number: Q8TPX3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families