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Q8TPX2 (RNP3_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 3

Short name=RNase P component 3
EC=3.1.26.5
Alternative name(s):
Rpp30
Gene names
Name:rnp3
Ordered Locus Names:MA_1782
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits Potential.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00756.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239Ribonuclease P protein component 3 HAMAP-Rule MF_00756
PRO_0000140038

Sequences

Sequence LengthMass (Da)Tools
Q8TPX2 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: A6C8470FCF0E638F

FASTA23926,214
        10         20         30         40         50         60 
MGKPKFYDFC VHAVPDGDST AQEQVSLGRH FGFSGIALAN HSDRLPDRKP ILPFIEGFEV 

        70         80         90        100        110        120 
FRGIELVEEN PSKLHSLIGK FRNSMDVLIV HGGSEAVNRA ALENPRVDIL NHPAFDRSSG 

       130        140        150        160        170        180 
LNQVLAKAAA ENGVAIGIIL RPLLHSRGSR RIRLLSDLKS NLELARKYDV SLVLCSDAMS 

       190        200        210        220        230 
CFDLRSPMEM LALAEVCGLE EDEALEAIST VPEKIIAKNR PGPGYIKKGI EVLEGEDLF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE010299 Genomic DNA. Translation: AAM05188.1.
RefSeqNP_616708.1. NC_003552.1.

3D structure databases

ProteinModelPortalQ8TPX2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING188937.MA1782.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM05188; AAM05188; MA_1782.
GeneID1473671.
KEGGmac:MA1782.

Phylogenomic databases

eggNOGCOG1603.
KOK03539.
OMAESFIAPG.
PhylomeDBQ8TPX2.

Enzyme and pathway databases

BioCycMACE188937:GI2O-1800-MONOMER.

Family and domain databases

HAMAPMF_00756. RNase_P_3.
InterProIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERPTHR13031. PTHR13031. 1 hit.
PfamPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP3_METAC
AccessionPrimary (citable) accession number: Q8TPX2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2002
Last modified: July 9, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families