Q8TPG4 (Q8TPG4_METAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate decarboxylase EMBL AAM05352.1

Gene names

Ordered Locus Names:

MA_1949

Organism

Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP] EMBL AAM05352.1

Taxonomic identifier

188937 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina › Methanosarcina acetivorans

Protein attributes

Sequence length	468 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000382
Sequence similarities	Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000382
Molecular function	Lyase RuleBase RU000382
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glutamate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glutamate decarboxylase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8TPG4 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: F021DA7448872C97	FASTA	468	53,077
	10 20 30 40 50 60 MISRKMNLES LDESKKYRVG AYSARYVPKT KEKGIPKYEF PEEGMSPRAA YQLVHDEQSL 70 80 90 100 110 120 DGNPFLNLAS FVNTWMEPEA DKLVMENISK NIIDIFEYPQ TSRVIHHNMV NMLGRLFNGH 130 140 150 160 170 180 HTDFVGTSTA GSSEAIMLGL LAHKWSWKKS GRGTDKPNII FGNDAHVCWD KFARYFDVDT 190 200 210 220 230 240 RKVPIDKDRR TITAEAVAER IDENTICVGC VLGTTFTGEI DPVKDINDLL LEYKEEKGWD 250 260 270 280 290 300 IPIHIDAASG GFILPFTEPD FEWDFRLERV KSINVSGHKY GLTYPGLGWL IFRNKNALPE 310 320 330 340 350 360 DLIFHVNYLG EMEDSYTLNF SGGSAMVAAQ YYNFLRFGRA GYTGIMKKIL AVSQDLAEKV 370 380 390 400 410 420 DRLGRFEMLN KGERLPIIAF RQKEKTGYSL LQLSHKLREK GWIVPAYCLP ENAADIEIMR 430 440 450 460 IVVRENLTPD MASIIVEDLE KACQFLENGT EAGAEKPCPS GKDMAHIC

References

[1]

"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity." Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P. , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B. Genome Res. 12:532-542(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010299 Genomic DNA. Translation: AAM05352.1.
RefSeq	NP_616872.1. NC_003552.1.
3D structure databases
HSSP	HSSP built from PDB template 1PMM based on UniProtKB P28302.
ProteinModelPortal	Q8TPG4.
ModBase	Search...
Protein-protein interaction databases
STRING	188937.MA1949.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM05352; AAM05352; MA_1949.
GeneID	1473838.
KEGG	mac:MA1949.
Phylogenomic databases
eggNOG	COG0076.
KO	K01580.
OMA	PMDKEHM.
ProtClustDB	CLSK538077.
Enzyme and pathway databases
BioCyc	MACE188937:GI2O-2009-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit.
InterPro	IPR010107. Glutamate_decarboxylase. IPR002129. PyrdxlP-dep_de-COase. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
PANTHER	PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfam	PF00282. Pyridoxal_deC. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8TPG4_METAC

Accession

Primary (citable) accession number: Q8TPG4

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)