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Q8TLP6 (TRPF_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:MA_2988
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Sequence caution

The sequence AAM06361.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154402

Sequences

Sequence LengthMass (Da)Tools
Q8TLP6 [UniParc].

Last modified March 25, 2003. Version 2.
Checksum: 08F18D35D2EEF893

FASTA23825,983
        10         20         30         40         50         60 
MKTRPKTRIK TRVKICGIRS PKDIEFAALY GADAVGFITE VPVESPRKLD SDTAAALISK 

        70         80         90        100        110        120 
VPKCLDSVMV IMPETSTSAL ELIEKVKPNI VQIHSDLPLS ELKAVREKAD IPIIKTLSVP 

       130        140        150        160        170        180 
AEQEAPKLHN IVTRLLEEVR ELEESGIVDS VLLDSGIAGK TGGTGCVHDW DLSRRIAEET 

       190        200        210        220        230 
ELPLILAGGL KPENVQEAIR SVSPYAVDTA SGVETQGKKD SVKVRKFIEE VRCTYAFL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE010299 Genomic DNA. Translation: AAM06361.1. Different initiation.
RefSeqNP_617881.1. NC_003552.1.

3D structure databases

ProteinModelPortalQ8TLP6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING188937.MA2988.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM06361; AAM06361; MA_2988.
GeneID1474882.
KEGGmac:MA2988.

Phylogenomic databases

eggNOGCOG0135.
KOK01817.
OMAETHDWER.
PhylomeDBQ8TLP6.
ProtClustDBCLSK450359.

Enzyme and pathway databases

BioCycMACE188937:GI2O-3021-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_METAC
AccessionPrimary (citable) accession number: Q8TLP6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 25, 2003
Last modified: April 16, 2014
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways