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Q8TLM4 (PDAD1_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Pyruvoyl-dependent arginine decarboxylase 1

Short name=PvlArgDC 1
EC=4.1.1.19
Gene names
Name:pdaD1
Ordered Locus Names:MA_3012
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-arginine = agmatine + CO2. HAMAP-Rule MF_01404

Cofactor

Pyruvoyl group By similarity. HAMAP-Rule MF_01404

Sequence similarities

Belongs to the PdaD family.

Ontologies

Keywords
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionarginine decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4444Pyruvoyl-dependent arginine decarboxylase 1 subunit beta By similarity
PRO_0000023310
Chain45 – 165121Pyruvoyl-dependent arginine decarboxylase 1 subunit alpha By similarity
PRO_0000023311

Sites

Site44 – 452Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue451Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8TLM4 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: CE50420335EE4139

FASTA16518,075
        10         20         30         40         50         60 
MITKLIPRKV FFTSGVGLHS EKLESFEVSL RDAGIEKFNL VTVSSILPPN CEIVTKEEGL 

        70         80         90        100        110        120 
KELSPGEVVF CVMSRISSNE PGKTLSTSVG CALPRDISKH GYISEYHAYE ENAQDVGEHA 

       130        140        150        160 
KKLAGSMYST WTNEAPLKTF SIPRSSSVQE SGDWMTVISA AVFII 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE010299 Genomic DNA. Translation: AAM06385.1.
RefSeqNP_617905.1. NC_003552.1.

3D structure databases

ProteinModelPortalQ8TLM4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING188937.MA3012.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM06385; AAM06385; MA_3012.
GeneID1474906.
KEGGmac:MA3012.

Phylogenomic databases

eggNOGCOG1945.
KOK02626.
OMAGYISEYH.
PhylomeDBQ8TLM4.
ProtClustDBPRK12398.

Enzyme and pathway databases

BioCycMACE188937:GI2O-3045-MONOMER.

Family and domain databases

Gene3D3.50.20.10. 1 hit.
HAMAPMF_01404. PvlArgDC.
InterProIPR016104. Pyr-dep_his/arg-deCO2ase.
IPR016105. Pyr-dep_his/arg-deCO2ase_sand.
IPR002724. Pyruvoyl-dep_arg_deCO2ase.
[Graphical view]
PfamPF01862. PvlArgDC. 1 hit.
[Graphical view]
PIRSFPIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDomPD010449. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56271. SSF56271. 1 hit.
TIGRFAMsTIGR00286. TIGR00286. 1 hit.
ProtoNetSearch...

Entry information

Entry namePDAD1_METAC
AccessionPrimary (citable) accession number: Q8TLM4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families