Q8TJQ0 (KAD6_METAC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative adenylate kinase
EC=2.7.4.3

Alternative name(s):
ATP-AMP transphosphorylase

Gene names

Ordered Locus Names:

MA_3730

Organism

Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)

Taxonomic identifier

188937 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00039
Sequence similarities	Belongs to the adenylate kinase family. AK6 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW adenylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Putative adenylate kinase HAMAP MF_00039		PRO_0000153905
Regions
	Nucleotide binding	7 – 14	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8TJQ0 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 4487C2F57D21434A	FASTA	186	21,160
	10 20 30 40 50 60 MLIGLTGTPG TGKTSVSKLL EKKRQWKIIH LNELIKEEHL YTEVDEKRDS VVADMELVRS 70 80 90 100 110 120 RLPELINEME KEPANKVVIL ESHLAHYITD IVIVLRAYPP ELKKRLEKRG YSEEKVNENA 130 140 150 160 170 180 EAESIDLILA EAFEWCDKVF EINTTGRTAE ETAGDVEKII DSLLSGKEEQ LQEYGPGSLD WIDSVP

References

[1]

"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity." Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P. , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B. Genome Res. 12:532-542(2002) [PubMed: 11932238] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE010299 Genomic DNA. Translation: AAM07082.1.
RefSeq	NP_618602.1. NC_003552.1.
3D structure databases
ProteinModelPortal	Q8TJQ0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1475623.
GenomeReviews	Gene locus MA_3730 in contig AE010299_GR.
KEGG	mac:MA3730.
NMPDR	fig|188937.1.peg.3628.
Phylogenomic databases
HOGENOM	HBG646389.
OMA	EILDVCL.
ProtClustDB	CLSK450466.
Enzyme and pathway databases
BioCyc	MACE188937:MA3730-MONOMER.
Family and domain databases
HAMAP	MF_00039. Put_adenyl_kinase. [Tree]
InterPro	IPR020618. Adenylate_kinase_putative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD6_METAC

Accession

Primary (citable) accession number: Q8TJQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	June 1, 2002
Last modified:	October 19, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program