Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Translation initiation factor 6

Gene

eif6

Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciMACE188937:G1FZT-4377-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 6UniRule annotation
Short name:
aIF-6UniRule annotation
Gene namesi
Name:eif6UniRule annotation
Ordered Locus Names:MA_4112
OrganismiMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Taxonomic identifieri188937 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000002487 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001537451 – 218Translation initiation factor 6Add BLAST218

Interactioni

Protein-protein interaction databases

STRINGi188937.MA4112

Structurei

3D structure databases

ProteinModelPortaliQ8TIN4
SMRiQ8TIN4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04176 Archaea
COG1976 LUCA
InParanoidiQ8TIN4
KOiK03264
OMAiNDWCAFT
OrthoDBiPOG093Z0C2O
PhylomeDBiQ8TIN4

Family and domain databases

CDDicd00527 IF6, 1 hit
HAMAPiMF_00032 eIF_6, 1 hit
InterProiView protein in InterPro
IPR002769 eIF6
PANTHERiPTHR10784 PTHR10784, 1 hit
PfamiView protein in Pfam
PF01912 eIF-6, 1 hit
PIRSFiPIRSF006413 IF-6, 1 hit
SMARTiView protein in SMART
SM00654 eIF6, 1 hit
TIGRFAMsiTIGR00323 eIF-6, 1 hit

Sequencei

Sequence statusi: Complete.

Q8TIN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRTVDIYDT SIIGVFATCT EDVVLVPPLT KPEVCALLEE VLDVRVIETL
60 70 80 90 100
VNGSIVVGAL SRGNSNGFML PYGARAEMQR FTDIPVGILP DRLNAVGNIV
110 120 130 140 150
FANDSAALVH PDLSDKALEA IARTLKVDVY RGTIAGIKNV GMAGVVTNKG
160 170 180 190 200
LLVHPKVTAS EREVLEKIFG FPVNIGTTNF GTQMLGSGLL ANSKNFVAGS
210
ETTGPELGRI EEALGFLE
Length:218
Mass (Da):23,141
Last modified:June 1, 2002 - v1
Checksum:iA13726B8D9A4597C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE010299 Genomic DNA Translation: AAM07460.1
RefSeqiWP_011024003.1, NC_003552.1

Genome annotation databases

EnsemblBacteriaiAAM07460; AAM07460; MA_4112
GeneIDi1476006
KEGGimac:MA_4112

Similar proteinsi

Entry informationi

Entry nameiIF6_METAC
AccessioniPrimary (citable) accession number: Q8TIN4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: June 1, 2002
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health