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Q8TIN4 (IF6_METAC) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor 6

Short name=aIF-6
Gene names
Name:eif6
Ordered Locus Names:MA_4112
OrganismMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) [Reference proteome] [HAMAP]
Taxonomic identifier188937 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length218 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex By similarity. HAMAP-Rule MF_00032

Sequence similarities

Belongs to the eIF-6 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Molecular functionInitiation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmature ribosome assembly

Inferred from electronic annotation. Source: InterPro

   Molecular_functionribosome binding

Inferred from electronic annotation. Source: InterPro

translation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 218218Translation initiation factor 6 HAMAP-Rule MF_00032
PRO_0000153745

Sequences

Sequence LengthMass (Da)Tools
Q8TIN4 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: A13726B8D9A4597C

FASTA21823,141
        10         20         30         40         50         60 
MIRTVDIYDT SIIGVFATCT EDVVLVPPLT KPEVCALLEE VLDVRVIETL VNGSIVVGAL 

        70         80         90        100        110        120 
SRGNSNGFML PYGARAEMQR FTDIPVGILP DRLNAVGNIV FANDSAALVH PDLSDKALEA 

       130        140        150        160        170        180 
IARTLKVDVY RGTIAGIKNV GMAGVVTNKG LLVHPKVTAS EREVLEKIFG FPVNIGTTNF 

       190        200        210 
GTQMLGSGLL ANSKNFVAGS ETTGPELGRI EEALGFLE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE010299 Genomic DNA. Translation: AAM07460.1.
RefSeqNP_618980.1. NC_003552.1.

3D structure databases

ProteinModelPortalQ8TIN4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING188937.MA4112.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM07460; AAM07460; MA_4112.
GeneID1476006.
KEGGmac:MA4112.

Phylogenomic databases

eggNOGCOG1976.
KOK03264.
OMAWLSDLFK.
PhylomeDBQ8TIN4.

Enzyme and pathway databases

BioCycMACE188937:GI2O-4162-MONOMER.

Family and domain databases

HAMAPMF_00032. eIF_6.
InterProIPR002769. eIF6.
[Graphical view]
PANTHERPTHR10784. PTHR10784. 1 hit.
PfamPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFPIRSF006413. IF-6. 1 hit.
SMARTSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsTIGR00323. eIF-6. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF6_METAC
AccessionPrimary (citable) accession number: Q8TIN4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: June 1, 2002
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries