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Q8TIN4

- IF6_METAC

UniProt

Q8TIN4 - IF6_METAC

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Protein

Translation initiation factor 6

Gene

eif6

Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

GO - Molecular functioni

  1. ribosome binding Source: InterPro
  2. translation initiation factor activity Source: UniProtKB-KW

GO - Biological processi

  1. mature ribosome assembly Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciMACE188937:GI2O-4162-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 6UniRule annotation
Short name:
aIF-6UniRule annotation
Gene namesi
Name:eif6UniRule annotation
Ordered Locus Names:MA_4112
OrganismiMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Taxonomic identifieri188937 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000002487: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Translation initiation factor 6PRO_0000153745Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi188937.MA4112.

Structurei

3D structure databases

ProteinModelPortaliQ8TIN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1976.
InParanoidiQ8TIN4.
KOiK03264.
OMAiWLSDLFK.
PhylomeDBiQ8TIN4.

Family and domain databases

HAMAPiMF_00032. eIF_6.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8TIN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRTVDIYDT SIIGVFATCT EDVVLVPPLT KPEVCALLEE VLDVRVIETL
60 70 80 90 100
VNGSIVVGAL SRGNSNGFML PYGARAEMQR FTDIPVGILP DRLNAVGNIV
110 120 130 140 150
FANDSAALVH PDLSDKALEA IARTLKVDVY RGTIAGIKNV GMAGVVTNKG
160 170 180 190 200
LLVHPKVTAS EREVLEKIFG FPVNIGTTNF GTQMLGSGLL ANSKNFVAGS
210
ETTGPELGRI EEALGFLE
Length:218
Mass (Da):23,141
Last modified:June 1, 2002 - v1
Checksum:iA13726B8D9A4597C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010299 Genomic DNA. Translation: AAM07460.1.
RefSeqiNP_618980.1. NC_003552.1.
WP_011024003.1. NC_003552.1.

Genome annotation databases

EnsemblBacteriaiAAM07460; AAM07460; MA_4112.
GeneIDi1476006.
KEGGimac:MA4112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE010299 Genomic DNA. Translation: AAM07460.1 .
RefSeqi NP_618980.1. NC_003552.1.
WP_011024003.1. NC_003552.1.

3D structure databases

ProteinModelPortali Q8TIN4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 188937.MA4112.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM07460 ; AAM07460 ; MA_4112 .
GeneIDi 1476006.
KEGGi mac:MA4112.

Phylogenomic databases

eggNOGi COG1976.
InParanoidi Q8TIN4.
KOi K03264.
OMAi WLSDLFK.
PhylomeDBi Q8TIN4.

Enzyme and pathway databases

BioCyci MACE188937:GI2O-4162-MONOMER.

Family and domain databases

HAMAPi MF_00032. eIF_6.
InterProi IPR002769. eIF6.
[Graphical view ]
PANTHERi PTHR10784. PTHR10784. 1 hit.
Pfami PF01912. eIF-6. 1 hit.
[Graphical view ]
PIRSFi PIRSF006413. IF-6. 1 hit.
SMARTi SM00654. eIF6. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00323. eIF-6. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity."
    Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.
    , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.
    Genome Res. 12:532-542(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

Entry informationi

Entry nameiIF6_METAC
AccessioniPrimary (citable) accession number: Q8TIN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3