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Q8TIN4

- IF6_METAC

UniProt

Q8TIN4 - IF6_METAC

Protein

Translation initiation factor 6

Gene

eif6

Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.UniRule annotation

    GO - Molecular functioni

    1. ribosome binding Source: InterPro
    2. translation initiation factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. mature ribosome assembly Source: InterPro

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciMACE188937:GI2O-4162-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor 6UniRule annotation
    Short name:
    aIF-6UniRule annotation
    Gene namesi
    Name:eif6UniRule annotation
    Ordered Locus Names:MA_4112
    OrganismiMethanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
    Taxonomic identifieri188937 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
    ProteomesiUP000002487: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 218218Translation initiation factor 6PRO_0000153745Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi188937.MA4112.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TIN4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eIF-6 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1976.
    KOiK03264.
    OMAiWLSDLFK.
    PhylomeDBiQ8TIN4.

    Family and domain databases

    HAMAPiMF_00032. eIF_6.
    InterProiIPR002769. eIF6.
    [Graphical view]
    PANTHERiPTHR10784. PTHR10784. 1 hit.
    PfamiPF01912. eIF-6. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006413. IF-6. 1 hit.
    SMARTiSM00654. eIF6. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00323. eIF-6. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8TIN4-1 [UniParc]FASTAAdd to Basket

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    MIRTVDIYDT SIIGVFATCT EDVVLVPPLT KPEVCALLEE VLDVRVIETL    50
    VNGSIVVGAL SRGNSNGFML PYGARAEMQR FTDIPVGILP DRLNAVGNIV 100
    FANDSAALVH PDLSDKALEA IARTLKVDVY RGTIAGIKNV GMAGVVTNKG 150
    LLVHPKVTAS EREVLEKIFG FPVNIGTTNF GTQMLGSGLL ANSKNFVAGS 200
    ETTGPELGRI EEALGFLE 218
    Length:218
    Mass (Da):23,141
    Last modified:June 1, 2002 - v1
    Checksum:iA13726B8D9A4597C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE010299 Genomic DNA. Translation: AAM07460.1.
    RefSeqiNP_618980.1. NC_003552.1.
    WP_011024003.1. NC_003552.1.

    Genome annotation databases

    EnsemblBacteriaiAAM07460; AAM07460; MA_4112.
    GeneIDi1476006.
    KEGGimac:MA4112.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE010299 Genomic DNA. Translation: AAM07460.1 .
    RefSeqi NP_618980.1. NC_003552.1.
    WP_011024003.1. NC_003552.1.

    3D structure databases

    ProteinModelPortali Q8TIN4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 188937.MA4112.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM07460 ; AAM07460 ; MA_4112 .
    GeneIDi 1476006.
    KEGGi mac:MA4112.

    Phylogenomic databases

    eggNOGi COG1976.
    KOi K03264.
    OMAi WLSDLFK.
    PhylomeDBi Q8TIN4.

    Enzyme and pathway databases

    BioCyci MACE188937:GI2O-4162-MONOMER.

    Family and domain databases

    HAMAPi MF_00032. eIF_6.
    InterProi IPR002769. eIF6.
    [Graphical view ]
    PANTHERi PTHR10784. PTHR10784. 1 hit.
    Pfami PF01912. eIF-6. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006413. IF-6. 1 hit.
    SMARTi SM00654. eIF6. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00323. eIF-6. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity."
      Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.
      , McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.
      Genome Res. 12:532-542(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35395 / DSM 2834 / JCM 12185 / C2A.

    Entry informationi

    Entry nameiIF6_METAC
    AccessioniPrimary (citable) accession number: Q8TIN4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3