Reviewed, UniProtKB/Swiss-Prot Q8TGY6 (RNP1_METKA)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 1
      Short name=RNase P component 1
    EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	MK1216

Organism

Methanopyrus kandleri [Complete proteome] [HAMAP]

Taxonomic identifier

2320 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanopyri › Methanopyrales › Methanopyraceae › Methanopyrus

Protein attributes

Sequence length	107 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 107	107	Ribonuclease P protein component 1 HAMAP MF_00754		PRO_0000128430

Sequences

	Sequence		Length	Mass (Da)
	Q8TGY6-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 8C0A1618430EBB42	FASTA	107	12,135
	10 20 30 40 50 60 MPITPRNIVR HELIGLECRV VKSLGPPYEG LEGRIVDETK NTLVLKTESG EKVIVKDQVL 70 80 90 100 LELKLPSGER VRVDGALLVG RPEERLSKRI KYAEVVRGRF DPEDYLD

References

[1]

"The complete genome of hyperthermophile Methanopyrus kandleri AV19 and monophyly of archaeal methanogens." Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N., Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A., Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G., Koonin E.V., Kozyavkin S.A. Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002) [PubMed: 11930014] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AV19 / DSM 6324 / JCM 9639 / NBRC 100938.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE009439 Genomic DNA. Translation: AAM02429.1.
RefSeq	NP_614499.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1477811.
GenomeReviews	Gene locus MK1216 in contig AE009439_GR.
KEGG	mka:MK1216.
NMPDR	fig|190192.1.peg.1212.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8TGY6.
OMA	VINETRN.
Enzyme and pathway databases
BioCyc	MKAN190192:MK1216-MON.
BRENDA	3.1.26.5. 7577.
Family and domain databases
HAMAP	MF_00754. [Tree]
InterPro	IPR002730. RNase_P/MRP_p29-sub_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
ProDom	PD009163. UPF0086. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

RNP1_METKA

Accession

Primary (citable) accession number: Q8TGY6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2004
Last sequence update:	June 1, 2002
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)