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Q8TGN9

- NAG1_YEAST

UniProt

Q8TGN9 - NAG1_YEAST

Protein

Protein NAG1

Gene

NAG1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Involved in yeast cell wall biogenesis.1 Publication

    GO - Biological processi

    1. cell wall biogenesis Source: SGD

    Keywords - Biological processi

    Cell wall biogenesis/degradation

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31015-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein NAG1
    Alternative name(s):
    Nested antisense gene 1 protein
    Gene namesi
    Name:NAG1
    Ordered Locus Names:YGR031C-A
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    SGDiS000028636. NAG1.

    Subcellular locationi

    Membrane Curated; Single-pass membrane protein Curated
    Note: Localizes to the cell periphery under conditions of vegetative growth.1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: SGD

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Hypersensitive to cell wall-perturbing agent calcofluor white (CFW) at 37 degrees Celsius. A similar phenotype is observed at 30 degrees Celsius, although the severity is decreased. Decreased expression of genes contributing to cell wall organization during vegetative growth.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 163163Protein NAG1PRO_0000299922Add
    BLAST

    Expressioni

    Inductioni

    Expression is dependent upon the presence of the cell wall integrity pathway mitogen-activated protein kinase SLT2 and its downstream transcription factor RLM1.1 Publication

    Gene expression databases

    GenevestigatoriQ8TGN9.

    Interactioni

    Protein-protein interaction databases

    STRINGi4932.YGR031C-A.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TGN9.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei76 – 9621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    OrthoDBiEOG741ZDV.

    Sequencei

    Sequence statusi: Complete.

    Q8TGN9-1 [UniParc]FASTAAdd to Basket

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    MNSAGRVHRS RAGSRGHAAI SPLTMASFSV ARGIRSSNVY DDTDDELSIL    50
    TFFSAVRRNR LTSSLPPILS ARCSSACFSV RIVLPLSLTI SISALMYSTN 100
    SALGRKLTGA FSIQTNIEQS CGFFRTSIMA TLPPIECPII IGPPLVFNSC 150
    FVIKCFTSSD MTS 163
    Length:163
    Mass (Da):17,536
    Last modified:June 1, 2002 - v1
    Checksum:iCEDDE53B47160CF8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ115390 Genomic DNA. Translation: AAZ22446.1.
    Z72816 Genomic DNA. No translation available.
    AF479950 Genomic DNA. Translation: AAL79263.1.
    BK006941 Genomic DNA. Translation: DAA08128.1.
    RefSeqiNP_001027023.1. NM_001184658.1.

    Genome annotation databases

    EnsemblFungiiYGR031C-A; YGR031C-A; YGR031C-A.
    GeneIDi8656591.
    KEGGisce:YGR031C-A.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ115390 Genomic DNA. Translation: AAZ22446.1 .
    Z72816 Genomic DNA. No translation available.
    AF479950 Genomic DNA. Translation: AAL79263.1 .
    BK006941 Genomic DNA. Translation: DAA08128.1 .
    RefSeqi NP_001027023.1. NM_001184658.1.

    3D structure databases

    ProteinModelPortali Q8TGN9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4932.YGR031C-A.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGR031C-A ; YGR031C-A ; YGR031C-A .
    GeneIDi 8656591.
    KEGGi sce:YGR031C-A.

    Organism-specific databases

    SGDi S000028636. NAG1.

    Phylogenomic databases

    OrthoDBi EOG741ZDV.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31015-MONOMER.

    Gene expression databases

    Genevestigatori Q8TGN9.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
      Deutschbauer A.M., Davis R.W.
      Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SK1.
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    5. "Unconventional genomic architecture in the budding yeast Saccharomyces cerevisiae masks the nested antisense gene NAG1."
      Ma J., Dobry C.J., Krysan D.J., Kumar A.
      Eukaryot. Cell 7:1289-1298(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION, FUNCTION, SUBCELLULAR LOCATION, INDUCTION, DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiNAG1_YEAST
    AccessioniPrimary (citable) accession number: Q8TGN9
    Secondary accession number(s): D6VUG7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Caution

    Overlaps completely with ORF YGR031W.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3