Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8TGJ3

- KISH_YEAST

UniProt

Q8TGJ3 - KISH_YEAST

Protein

Protein kish

Gene

KSH1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    Involved in the early part of the secretory pathway.1 Publication

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33410-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein kish
    Gene namesi
    Name:KSH1
    Ordered Locus Names:YNL024C-A
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIV

    Organism-specific databases

    CYGDiYNL024c-a.
    SGDiS000028698. KSH1.

    Subcellular locationi

    Endoplasmic reticulum membrane By similarity; Single-pass type I membrane protein By similarity. Golgi apparatus membrane 1 Publication; Single-pass type I membrane protein 1 Publication

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    2. Golgi membrane Source: UniProtKB-SubCell
    3. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Endoplasmic reticulum, Golgi apparatus, Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Inviable.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 7246Protein kishPRO_0000247775Add
    BLAST

    Proteomic databases

    MaxQBiQ8TGJ3.
    PaxDbiQ8TGJ3.

    Expressioni

    Gene expression databases

    GenevestigatoriQ8TGJ3.

    Interactioni

    Protein-protein interaction databases

    BioGridi37058. 5 interactions.
    STRINGi4932.YNL024C-A.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TGJ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini27 – 5327LumenalSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei54 – 7219HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KISH family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG146442.
    GeneTreeiENSGT00730000111214.
    OMAiYINGNTL.
    OrthoDBiEOG75MW8M.

    Family and domain databases

    InterProiIPR009653. DUF1242.
    [Graphical view]
    PANTHERiPTHR13229. PTHR13229. 1 hit.
    PfamiPF06842. DUF1242. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8TGJ3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSALFNFRSL LQVILLLICS CSYVHGQWPS LLDRYKNHEV LGAFWKMARV   50
    GERASPYVSL ACILMAISQF NS 72
    Length:72
    Mass (Da):8,196
    Last modified:June 1, 2002 - v1
    Checksum:i5645433999B16B27
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z71300 Genomic DNA. No translation available.
    Z71301 Genomic DNA. No translation available.
    AF480014 Genomic DNA. Translation: AAL79327.1.
    BK006947 Genomic DNA. Translation: DAA10520.1.
    RefSeqiNP_878158.3. NM_001184619.3.

    Genome annotation databases

    EnsemblFungiiYNL024C-A; YNL024C-A; YNL024C-A.
    GeneIDi1466516.
    KEGGisce:YNL024C-A.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z71300 Genomic DNA. No translation available.
    Z71301 Genomic DNA. No translation available.
    AF480014 Genomic DNA. Translation: AAL79327.1 .
    BK006947 Genomic DNA. Translation: DAA10520.1 .
    RefSeqi NP_878158.3. NM_001184619.3.

    3D structure databases

    ProteinModelPortali Q8TGJ3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 37058. 5 interactions.
    STRINGi 4932.YNL024C-A.

    Proteomic databases

    MaxQBi Q8TGJ3.
    PaxDbi Q8TGJ3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YNL024C-A ; YNL024C-A ; YNL024C-A .
    GeneIDi 1466516.
    KEGGi sce:YNL024C-A.

    Organism-specific databases

    CYGDi YNL024c-a.
    SGDi S000028698. KSH1.

    Phylogenomic databases

    eggNOGi NOG146442.
    GeneTreei ENSGT00730000111214.
    OMAi YINGNTL.
    OrthoDBi EOG75MW8M.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33410-MONOMER.

    Miscellaneous databases

    NextBioi 983766.
    PROi Q8TGJ3.

    Gene expression databases

    Genevestigatori Q8TGJ3.

    Family and domain databases

    InterProi IPR009653. DUF1242.
    [Graphical view ]
    PANTHERi PTHR13229. PTHR13229. 1 hit.
    Pfami PF06842. DUF1242. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
      Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
      , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
      Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    4. "A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway."
      Wendler F., Gillingham A.K., Sinka R., Rosa-Ferreira C., Gordon D.E., Franch-Marro X., Peden A.A., Vincent J.P., Munro S.
      EMBO J. 29:304-314(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPE.

    Entry informationi

    Entry nameiKISH_YEAST
    AccessioniPrimary (citable) accession number: Q8TGJ3
    Secondary accession number(s): D6W1F4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 25, 2006
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIV
      Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

    External Data

    Dasty 3