Q8TFL9 (Q8TFL9_TALEM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cellobiohydrolase 1 catalytic domain EMBL AAL33603.2
EC=3.2.1.91 EMBL AAL33603.2

Submitted name:
Cellobiohydrolase I catalytic domain EMBL AAL89553.1
EC=3.2.1.91 EMBL AAL89553.1

Gene names

Name:	cbh1 EMBL AAL89553.1
Synonyms:	cbh1A EMBL AAL33603.2

Organism

Talaromyces emersonii EMBL AAL89553.1

Taxonomic identifier

68825 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Talaromyces

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Glycosidase EMBL AAL89553.1 Hydrolase
Technical term	3D-structure PDB 1Q9H
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cellulose 1,4-beta-cellobiosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Glycosylation	285	1	N-linked (GlcNAc...) PDB 1Q9H
	Glycosylation	449	1	N-linked (GlcNAc...) PDB 1Q9H

Sequences

	Sequence		Length	Mass (Da)
	Q8TFL9 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 6DFABF6B8A545840	FASTA	455	48,737
	10 20 30 40 50 60 MLRRALLLSS SAILAVKAQQ AGTATAENHP PLTWQECTAP GSCTTQNGAV VLDANWRWVH 70 80 90 100 110 120 DVNGYTNCYT GNTWDPTYCP DDETCAQNCA LDGADYEGTY GVTSSGSSLK LNFVTGSNVG 130 140 150 160 170 180 SRLYLLQDDS TYQIFKLLNR EFSFDVDVSN LPCGLNGALY FVAMDADGGV SKYPNNKAGA 190 200 210 220 230 240 KYGTGYCDSQ CPRDLKFIDG EANVEGWQPS SNNANTGIGD HGSCCAEMDV WEANSISNAV 250 260 270 280 290 300 TPHPCDTPGQ TMCSGDDCGG TYSNDRYAGT CDPDGCDFNP YRMGNTSFYG PGKIIDTTKP 310 320 330 340 350 360 FTVVTQFLTD DGTDTGTLSE IKRFYIQNSN VIPQPNSDIS GVTGNSITTE FCTAQKQAFG 370 380 390 400 410 420 DTDDFSQHGG LAKMGAAMQQ GMVLVMSLWD DYAAQMLWLD SDYPTDADPT TPGIARGTCP 430 440 450 TDSGVPSDVE SQSPNSYVTY SNIKFGPINS TFTAS

References

[1]	"Three-dimensional structure of a thermostable native cellobiohydrolase, CBH IB, and molecular characterization of the cel7 gene from the filamentous fungus, Talaromyces emersonii." Grassick A., Murray P.G., Thompson R., Collins C.M., Byrnes L., Birrane G., Higgins T.M., Tuohy M.G. Eur. J. Biochem. 271:4495-4506(2004) [PubMed: 15560790] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 20-455, GLYCOSYLATION AT ASN-285 AND ASN-449.
[2]	"Molecular cloning of the cellobiohydrolase genes of Talaromyces emersonii." Collins C.M., Murray P.G., Tuohy M.G. Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"The molecular cloning of the cellobiohydrolases of Talaromyces emersonii." Collins C.M., Murray P.G., Denman S., Grassick A., Teeri T.T., Byrnes L., Tuohy M.G. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF439935 Genomic DNA. Translation: AAL33603.2.
AY081766 mRNA. Translation: AAL89553.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1Q9H	X-ray	2.35	A	20-455	[»]
3PFJ	X-ray	1.36	A	20-455	[»]
3PFX	X-ray	1.26	A	20-455	[»]
3PFZ	X-ray	1.10	A	20-455	[»]

ProteinModelPortal

Q8TFL9.

SMR

Q8TFL9. Positions 19-453.

ModBase

Search...

Protein family/group databases

CAZy

GH7. Glycoside Hydrolase Family 7.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR008985. ConA-like_lec_gl.
IPR001722. Glyco_hydro_7.
[Graphical view]

Gene3D

G3DSA:2.70.100.10. Glyco_hydro_7. 1 hit.

Pfam

PF00840. Glyco_hydro_7. 1 hit.
[Graphical view]

PRINTS

PR00734. GLHYDRLASE7.

SUPFAM

SSF49899. ConA_like_lec_gl. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q8TFL9_TALEM

Accession

Primary (citable) accession number: Q8TFL9
Secondary accession number(s): Q8X210

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)