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Protein

Fas-binding factor 1

Gene

FBF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis.2 Publications

GO - Biological processi

  • apical junction assembly Source: UniProtKB
  • cilium assembly Source: UniProtKB
  • establishment of epithelial cell polarity Source: UniProtKB
  • organelle organization Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Cilium biogenesis/degradation

Enzyme and pathway databases

ReactomeiR-HSA-5620912. Anchoring of the basal body to the plasma membrane.

Names & Taxonomyi

Protein namesi
Recommended name:
Fas-binding factor 1
Short name:
FBF-1
Alternative name(s):
Protein albatross
Gene namesi
Name:FBF1
Synonyms:ALB, KIAA1863
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:24674. FBF1.

Subcellular locationi

GO - Cellular componenti

  • cell junction Source: UniProtKB-SubCell
  • centriole Source: UniProtKB
  • centrosome Source: HPA
  • ciliary transition fiber Source: MGI
  • cytosol Source: Reactome
  • spindle pole Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cytoplasm, Cytoskeleton

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiFBF1.
DMDMi156630449.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11331133Fas-binding factor 1PRO_0000297646Add
BLAST

Proteomic databases

EPDiQ8TES7.
MaxQBiQ8TES7.
PaxDbiQ8TES7.
PRIDEiQ8TES7.

PTM databases

iPTMnetiQ8TES7.
PhosphoSiteiQ8TES7.

Expressioni

Tissue specificityi

Present in various epithelial cells (at protein level).

Gene expression databases

BgeeiQ8TES7.
CleanExiHS_FBF1.
ExpressionAtlasiQ8TES7. baseline and differential.
GenevisibleiQ8TES7. HS.

Organism-specific databases

HPAiHPA023677.

Interactioni

Subunit structurei

May interact with FAS cytoplasmic domain (By similarity). Interacts with PARD3.By similarity1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
ABI3Q9P2A43EBI-10244131,EBI-742038
AESQ081173EBI-10244131,EBI-717810
BLZF1Q9H2G93EBI-10244131,EBI-2548012
CALCOCO2Q131373EBI-10244131,EBI-739580
CCDC102BA1A4H13EBI-10244131,EBI-10171570
CCDC67E9PJR53EBI-10244131,EBI-10177066
CCDC67Q05D603EBI-10244131,EBI-748597
CEP55D3DR373EBI-10244131,EBI-10173536
CEP63Q96MT83EBI-10244131,EBI-741977
CINPQ9BW663EBI-10244131,EBI-739784
FAM208BQ5VWN6-23EBI-10244131,EBI-10172380
GATA1P159763EBI-10244131,EBI-3909284
GOLGA2Q083793EBI-10244131,EBI-618309
IKZF3Q9UKT93EBI-10244131,EBI-747204
KRT13A1A4E93EBI-10244131,EBI-10171552
KRT31Q153233EBI-10244131,EBI-948001
KRT40Q6A1623EBI-10244131,EBI-10171697
LZTS2Q9BRK43EBI-10244131,EBI-741037
MEOX2A4D1273EBI-10244131,EBI-10172134
MID2Q9UJV3-23EBI-10244131,EBI-10172526
MIPOL1Q8TD103EBI-10244131,EBI-2548751
PNMA1Q8ND903EBI-10244131,EBI-302345
RBPMSQ930623EBI-10244131,EBI-740322
SSX2IPQ9Y2D83EBI-10244131,EBI-2212028
SUMO1P631653EBI-10244131,EBI-80140
TADA2AO754783EBI-10244131,EBI-742268
TEX11Q8IYF33EBI-10244131,EBI-742397
TMCC2Q7Z6C63EBI-10244131,EBI-10177480
TRAF1Q130773EBI-10244131,EBI-359224
TRIM23P364063EBI-10244131,EBI-740098
TRIM27P143733EBI-10244131,EBI-719493
TRIM54Q9BYV23EBI-10244131,EBI-2130429
TSGA10Q9BZW73EBI-10244131,EBI-744794
TTC32Q5I0X73EBI-10244131,EBI-8636434
USHBP1Q8N6Y03EBI-10244131,EBI-739895
VPS37BQ9H9H43EBI-10244131,EBI-4400866

Protein-protein interaction databases

BioGridi124465. 146 interactions.
IntActiQ8TES7. 128 interactions.
MINTiMINT-1413885.
STRINGi9606.ENSP00000324292.

Structurei

3D structure databases

ProteinModelPortaliQ8TES7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili577 – 727151Sequence analysisAdd
BLAST
Coiled coili773 – 87098Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi999 – 104547Gln-richAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IFRT. Eukaryota.
ENOG4111RN4. LUCA.
GeneTreeiENSGT00720000108861.
HOGENOMiHOG000060115.
HOVERGENiHBG071428.
InParanoidiQ8TES7.
KOiK16471.
OrthoDBiEOG7HB58X.
PhylomeDBiQ8TES7.
TreeFamiTF328742.

Sequences (6)i

Sequence statusi: Complete.

This entry describes 6 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q8TES7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPKTKKGCK VTLPEKPVKL ASHTRDTTGV SQMFPSSKAR TKSLLGDDVF
60 70 80 90 100
STMAGLEEAD AEVSGISEAD PQALLQAMKD LDGMDADILG LKKSNSAPSK
110 120 130 140 150
KAAKDPGKGE LPNHPKPAGG AIPTKKSLPS PSSSGHQNRR FSSEDLEDPL
160 170 180 190 200
RGLLSYDEGG ITKQPPVTQS KTASDKSPST VRDQGPSIPL TPGDTPIRKK
210 220 230 240 250
EELLFDDGDD IMATLGFGDS PKAEKRQIGD QEGPRPARST LDELLGRGMA
260 270 280 290 300
TKLLARPGTG EHREFKLDKK YQRPQDSEDM WGDEDFTFGA YQPTVVSSEG
310 320 330 340 350
RQSRRQSVSR FFADSGADPK GEPGSKQSPP MASSPIQPRK GGADWLGLKD
360 370 380 390 400
EDLDLFPASP TREAHRESSV PVTPSVPPPA SQHSTPAGLP PSRAKPPTEG
410 420 430 440 450
AGSPAKASQA SKLRASKEEK EDWLSHALSR KKSQGLAREQ HAGTSEGLHL
460 470 480 490 500
AGTAGHPPSG SQPLTSTQGL EHAAAGGSSG TTARERPCVR PGVSGSPVTQ
510 520 530 540 550
NHAASALPTG SPKRGTAPGD LSATEPATCF PSTQKPTEPS VPVQPLLPES
560 570 580 590 600
LARSLLPSTE YQKQLLAAQV QLQCSPAELQ AELLHSQARL AELEAQVRKL
610 620 630 640 650
ELERAQHELL LGSLQQQHQA DLELIESAHR SRIKVLETSY QQREERLRRE
660 670 680 690 700
NEELSARYLS QCQEAEQARA ELTAQHQRRL AAIAQEKDQE MERLRELQRA
710 720 730 740 750
SILDMRRDHE EQLQRLKLLK DREVDAATSA TSHTRSLNSI IHQMEKFSSS
760 770 780 790 800
LHELSSRVEA SHLTTSQERE LGIRQRDEQL RALQERLGQQ QRDMEEERSR
810 820 830 840 850
QQEVIGKMEA RLNEQSRLLE QERWRVTAEQ SKAESMQRAL EEQRKVTAQQ
860 870 880 890 900
MAMERAELER AKSALLEEQK SVMLKCGEER RRLAAEWAEF SAQQKLSKER
910 920 930 940 950
AEREAERALQ VDTQREGTLI SLAKQAELKI RASELRAEEK QLAAERAALE
960 970 980 990 1000
QERQELRLEK ERINATALRV KLRAEEVESM SKVASEKYEE GERALREAQQ
1010 1020 1030 1040 1050
VQAEQQARLQ AVQQQQERLR KQEQHMHQEH LSLAQQRLQL DRARQDLPSS
1060 1070 1080 1090 1100
LVGLFPRAQG PAASSQSALM PPAPTTRWCS QPPTGLDPSP LHLHARLALL
1110 1120 1130
RHMAEQDRDF LENEQFFLET LKKGSYNLTS HSA
Length:1,133
Mass (Da):125,446
Last modified:August 21, 2007 - v2
Checksum:i58FA2446CBA3C6B7
GO
Isoform 2 (identifier: Q8TES7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     897-899: SKE → RAG
     900-1133: Missing.

Note: No experimental confirmation available.
Show »
Length:899
Mass (Da):98,643
Checksum:i3C216940C6ED257C
GO
Isoform 3 (identifier: Q8TES7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     599-662: KLELERAQHE...ELSARYLSQC → GSGAVGAGGR...AEAGARTGPA
     663-1133: Missing.

Note: No experimental confirmation available.
Show »
Length:662
Mass (Da):69,178
Checksum:i46F943597FC16193
GO
Isoform 4 (identifier: Q8TES7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     462-517: QPLTSTQGLE...PTGSPKRGTA → LTWAFCHLHL...VSGLVSRGPL
     518-1133: Missing.

Note: No experimental confirmation available.
Show »
Length:514
Mass (Da):54,791
Checksum:iEC7D6EF77AE2AE30
GO
Isoform 5 (identifier: Q8TES7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     309-309: Missing.
     924-924: K → KE

Note: No experimental confirmation available.
Show »
Length:1,133
Mass (Da):125,488
Checksum:i0FA5464A6C80D1A4
GO
Isoform 6 (identifier: Q8TES7-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     11-11: V → GSIDDFLGDLLGDDM
     924-924: K → KE

Show »
Length:1,148
Mass (Da):127,041
Checksum:i030249D5E297C457
GO

Sequence cautioni

The sequence BAB71400.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB84871.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti801 – 8011Q → R in BAB71400 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti65 – 651G → V.1 Publication
Corresponds to variant rs1135889 [ dbSNP | Ensembl ].
VAR_034659
Natural varianti151 – 1511R → G.2 Publications
Corresponds to variant rs2305913 [ dbSNP | Ensembl ].
VAR_034660
Natural varianti371 – 3711P → S.
Corresponds to variant rs7218738 [ dbSNP | Ensembl ].
VAR_034661
Natural varianti574 – 5741C → S.
Corresponds to variant rs7213548 [ dbSNP | Ensembl ].
VAR_034662

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei11 – 111V → GSIDDFLGDLLGDDM in isoform 6. 1 PublicationVSP_041555
Alternative sequencei309 – 3091Missing in isoform 5. CuratedVSP_040769
Alternative sequencei462 – 51756QPLTS…KRGTA → LTWAFCHLHLERCLSSANLS PAHKGLSTQLLEGVLEQLHE KDRVSGLVSRGPL in isoform 4. 1 PublicationVSP_027318Add
BLAST
Alternative sequencei518 – 1133616Missing in isoform 4. 1 PublicationVSP_027319Add
BLAST
Alternative sequencei599 – 66264KLELE…YLSQC → GSGAVGAGGRVATGGDTESG WKLPQEGGRAVGTGQRGVQP PPLPGCWPSCCLPGAEAGAR TGPA in isoform 3. 1 PublicationVSP_027320Add
BLAST
Alternative sequencei663 – 1133471Missing in isoform 3. 1 PublicationVSP_027321Add
BLAST
Alternative sequencei897 – 8993SKE → RAG in isoform 2. 1 PublicationVSP_027322
Alternative sequencei900 – 1133234Missing in isoform 2. 1 PublicationVSP_027323Add
BLAST
Alternative sequencei924 – 9241K → KE in isoform 5 and isoform 6. 1 PublicationVSP_040770

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB354594 mRNA. Translation: BAG71501.1.
AK057261 mRNA. Translation: BAB71400.1. Different initiation.
AK074045 mRNA. Translation: BAB84871.1. Different initiation.
AC087289 Genomic DNA. No translation available.
AB058766 mRNA. Translation: BAB47492.1.
BC007570 mRNA. Translation: AAH07570.1.
CCDSiCCDS45779.1. [Q8TES7-6]
RefSeqiNP_001074011.1. NM_001080542.1. [Q8TES7-5]
NP_001306122.1. NM_001319193.1. [Q8TES7-6]
UniGeneiHs.720068.

Genome annotation databases

EnsembliENST00000586717; ENSP00000465132; ENSG00000188878. [Q8TES7-1]
ENST00000627351; ENSP00000486708; ENSG00000281844. [Q8TES7-5]
GeneIDi85302.
KEGGihsa:85302.
UCSCiuc002jqd.2. human. [Q8TES7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB354594 mRNA. Translation: BAG71501.1.
AK057261 mRNA. Translation: BAB71400.1. Different initiation.
AK074045 mRNA. Translation: BAB84871.1. Different initiation.
AC087289 Genomic DNA. No translation available.
AB058766 mRNA. Translation: BAB47492.1.
BC007570 mRNA. Translation: AAH07570.1.
CCDSiCCDS45779.1. [Q8TES7-6]
RefSeqiNP_001074011.1. NM_001080542.1. [Q8TES7-5]
NP_001306122.1. NM_001319193.1. [Q8TES7-6]
UniGeneiHs.720068.

3D structure databases

ProteinModelPortaliQ8TES7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124465. 146 interactions.
IntActiQ8TES7. 128 interactions.
MINTiMINT-1413885.
STRINGi9606.ENSP00000324292.

PTM databases

iPTMnetiQ8TES7.
PhosphoSiteiQ8TES7.

Polymorphism and mutation databases

BioMutaiFBF1.
DMDMi156630449.

Proteomic databases

EPDiQ8TES7.
MaxQBiQ8TES7.
PaxDbiQ8TES7.
PRIDEiQ8TES7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000586717; ENSP00000465132; ENSG00000188878. [Q8TES7-1]
ENST00000627351; ENSP00000486708; ENSG00000281844. [Q8TES7-5]
GeneIDi85302.
KEGGihsa:85302.
UCSCiuc002jqd.2. human. [Q8TES7-1]

Organism-specific databases

CTDi85302.
GeneCardsiFBF1.
HGNCiHGNC:24674. FBF1.
HPAiHPA023677.
neXtProtiNX_Q8TES7.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFRT. Eukaryota.
ENOG4111RN4. LUCA.
GeneTreeiENSGT00720000108861.
HOGENOMiHOG000060115.
HOVERGENiHBG071428.
InParanoidiQ8TES7.
KOiK16471.
OrthoDBiEOG7HB58X.
PhylomeDBiQ8TES7.
TreeFamiTF328742.

Enzyme and pathway databases

ReactomeiR-HSA-5620912. Anchoring of the basal body to the plasma membrane.

Miscellaneous databases

GenomeRNAii85302.
NextBioi75787.
PROiQ8TES7.

Gene expression databases

BgeeiQ8TES7.
CleanExiHS_FBF1.
ExpressionAtlasiQ8TES7. baseline and differential.
GenevisibleiQ8TES7. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The keratin-binding protein Albatross regulates polarization of epithelial cells."
    Sugimoto M., Inoko A., Shiromizu T., Nakayama M., Zou P., Yonemura S., Hayashi Y., Izawa I., Sasoh M., Uji Y., Kaibuchi K., Kiyono T., Inagaki M.
    J. Cell Biol. 183:19-28(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6), FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH PARD3, VARIANTS VAL-65 AND GLY-151.
    Tissue: Lung.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 659-1133 (ISOFORM 2).
    Tissue: Spleen and Testis.
  3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Nakayama M., Nakajima D., Kikuno R., Ohara O.
    DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 63-1133 (ISOFORM 4), VARIANT GLY-151.
    Tissue: Brain.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 445-1133 (ISOFORM 1).
    Tissue: Muscle.
  6. "A novel protein (Fbf-1) that binds to CD95/APO-1/FAS and shows sequence similarity to trichohyalin and plectin."
    Schmidt T., Karsunky H., Frass B., Baum W., Denzel A., Moeroey T.
    Biochim. Biophys. Acta 1493:249-254(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods."
    Jakobsen L., Vanselow K., Skogs M., Toyoda Y., Lundberg E., Poser I., Falkenby L.G., Bennetzen M., Westendorf J., Nigg E.A., Uhlen M., Hyman A.A., Andersen J.S.
    EMBO J. 30:1520-1535(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  9. "Centriole distal appendages promote membrane docking, leading to cilia initiation."
    Tanos B.E., Yang H.J., Soni R., Wang W.J., Macaluso F.P., Asara J.M., Tsou M.F.
    Genes Dev. 27:163-168(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiFBF1_HUMAN
AccessioniPrimary (citable) accession number: Q8TES7
Secondary accession number(s): B5MEM5
, Q96IF6, Q96JG4, Q96MA8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: August 21, 2007
Last modified: May 11, 2016
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.