Reviewed, UniProtKB/Swiss-Prot Q8TEP8 (CE192_HUMAN)

Names and origin

Protein names

Recommended name:
    Centrosomal protein of 192 kDa
      Short name=Cep192

Gene names

Name:	CEP192
Synonyms:	KIAA1569
ORF Names:	PP8407

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1941 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication. Ref.9 Ref.10
Subunit structure	Interacts with SHBG. Ref.7
Subcellular location	Cytoplasm › cytoskeleton › centrosome › centriole. Note: Pericentriolar location in mitotic centrosomes. Ref.9 Ref.10 Ref.6
Sequence caution	The sequence CAB66752.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence CAB66752.1 differs from that shown. Reason: Frameshift at positions 1196 and 1239.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Coding sequence diversity	Alternative splicing Polymorphism
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytosol Inferred from Experiment. Source: Reactome
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q8TEP8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q8TEP8-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1403-1407: ALLHK → QGPAT
     1408-1941: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1941	1941	Centrosomal protein of 192 kDa		PRO_0000312495
Amino acid modifications
	Modified residue	1155	1	Phosphoserine Ref.8
	Modified residue	1159	1	Phosphoserine Ref.8
	Modified residue	1514	1	Phosphoserine
Natural variations
	Alternative sequence	1403 – 1407	5	ALLHK → QGPAT in isoform 2.		VSP_029845
	Alternative sequence	1408 – 1941	534	Missing in isoform 2.		VSP_029846
	Natural variant	457	1	T → A: dbSNP rs10048340.		VAR_037514
	Natural variant	513	1	Q → P: dbSNP rs11080623.		VAR_050782
	Natural variant	769	1	V → M: dbSNP rs2282542. Ref.2		VAR_037515
	Natural variant	948	1	R → H: dbSNP rs7228940. Ref.2 Ref.4		VAR_050783
	Natural variant	956	1	S → P: dbSNP rs578208. Ref.2 Ref.4 Ref.3		VAR_050784
	Natural variant	1105	1	L → F: dbSNP rs6505780. Ref.2 Ref.4 Ref.3		VAR_050785
	Natural variant	1455	1	S → N: dbSNP rs2027698. Ref.3		VAR_050786
	Natural variant	1525	1	L → P: dbSNP rs474337. Ref.2 Ref.3 Ref.5		VAR_050787
	Natural variant	1675	1	K → E: dbSNP rs3737379. Ref.3		VAR_050788
	Natural variant	1853	1	R → L: dbSNP rs1786263. Ref.2 Ref.3 Ref.5		VAR_050789
Experimental info
	Sequence conflict	806	1	R → L in BAB84900. Ref.3
	Sequence conflict	857	1	P → A in AAL55870. Ref.4
	Sequence conflict	1519	1	R → Q Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 4, 2007. Version 2. Checksum: 0DA715D1FAABA8D4	FASTA	1,941	213,146
	10 20 30 40 50 60 MKTSDLVPSF GYFIRSPEKR EPIALIRKSD VSRGNLEKEM AHLNHDLYSG DLNEQSQAQL 70 80 90 100 110 120 SEGSITLQVE AVESTSQVDE NDVTLTADKG KTEDTFFMSN KPQRYKDKLP DSGDSMLRIS 130 140 150 160 170 180 TIASAIAEAS VNTDPSQLAA MIKALSNKTR DKTFQEDEKQ KDYSHVRHFL PNDLEKSNGS 190 200 210 220 230 240 NALDMEKYLK KTEVSRYESA LENFSRASMS DTWDLSLPKE QTTQDIHPVD LSATSVSVRA 250 260 270 280 290 300 PEENTAAIVY VENGESENQE SFRTINSSNS VTNRENNSAV VDVKTCSIDN KLQDVGNDEK 310 320 330 340 350 360 ATSISTPSDS YSSVRNPRIT SLCLLKDCEE IRDNRENQRQ NECVSEISNS EKHVTFENHR 370 380 390 400 410 420 IVSPKNSDLK NTSPEHGGRG SEDEQESFRP STSPLSHSSP SEISGTSSSG CALESFGSAA 430 440 450 460 470 480 QQQQPPCEQE LSPLVCSPAG VSRLTYVSEP ESSYPTTATD DALEDRKSDI TSELSTTIIQ 490 500 510 520 530 540 GSPAALEERA MEKLREKVPF QNRGKGTLSS IIQNNSDTRK ATETTSLSSK PEYVKPDFRW 550 560 570 580 590 600 SKDPSSKSGN LLETSEVGWT SNPEELDPIR LALLGKSGLS CQVGSATSHP VSCQEPIDED 610 620 630 640 650 660 QRISPKDKST AGREFSGQVS HQTTSENQCT PIPSSTVHSS VADMQNMPAA VHALLTQPSL 670 680 690 700 710 720 SAAPFAQRYL GTLPSTGSTT LPQCHAGNAT VCGFSGGLPY PAVAGEPVQN SVAVGICLGS 730 740 750 760 770 780 NIGSGWMGTS SLCNPYSNTL NQNLLSTTKP FPVPSVGTNC GIEPWDSGVT SGLGSVRVPE 790 800 810 820 830 840 ELKLPHACCV GIASQTLLSV LNPTDRWLQV SIGVLSISVN GEKVDLSTYR CLVFKNKAII 850 860 870 880 890 900 RPHATEEIKV LFIPSSPGVF RCTFSVASWP CSTDAETIVQ AEALASTVTL TAIAESPVIE 910 920 930 940 950 960 VETEKKDVLD FGDLTYGGWK ALPLKLINRT HATVPIRLII NANAVAWRCF TFSKESVRAP 970 980 990 1000 1010 1020 VEVAPCADVV TRLAGPSVVN HMMPASYDGQ DPEFLMIWVL FHSPKKQISS SDILDSAEEF 1030 1040 1050 1060 1070 1080 SAKVDIEVDS PNPTPVLRSV SLRARAGIAR IHAPRDLQTM HFLAKVASSR KQHLPLKNAG 1090 1100 1110 1120 1130 1140 NIEVYLDIKV PEQGSHFSVD PKNLLLKPGE EHEVIVSFTP KDPEACEERI LKIFVQPFGP 1150 1160 1170 1180 1190 1200 QYEVVLKGEV ISSGSKPLSP GPCLDIPSIL SNKQFLAWGG VPLGRTQLQK LALRNNSAST 1210 1220 1230 1240 1250 1260 TQHLRLLIRG QDQDCFQLQN TFGSEQRLTS NCEIRIHPKE DIFISVLFAP TRLSCMLARL 1270 1280 1290 1300 1310 1320 EIKQLGNRSQ PGIKFTIPLS GYGGTSNLIL EGVKKLSDSY MVTVNGLVPG KESKIVFSVR 1330 1340 1350 1360 1370 1380 NTGSRAAFVK AVGFKDSQKK VLLDPKVLRI FPDKFVLKER TQENVTLIYN PSDRGINNKT 1390 1400 1410 1420 1430 1440 ATELSTVYLF GGDEISRQQY RRALLHKPEM IKQILPEHSV LQNINFVEAF QDELLVTEVY 1450 1460 1470 1480 1490 1500 DLPQRPNDVQ LFYGSMCKII LSVIGEFRDC ISSREFLQPS SKASLESTSD LGASGKHGGN 1510 1520 1530 1540 1550 1560 VSLDVLPVKG PQGSPLLSRA ARPPLDQLAS EEPWTVLPEH LILVAPSPCD MAKTGRFQIV 1570 1580 1590 1600 1610 1620 NNSVRLLRFE LCWPAHCLTV TPQHGCVAPE SKLQILVSPN SSLSTKQSMF PWSGLIYIHC 1630 1640 1650 1660 1670 1680 DDGQKKIVKV QIREDLTQVE LLTRLTSKPF GILSPVSEPS VSHLVKPMTK PPSTKVEIRN 1690 1700 1710 1720 1730 1740 KSITFPTTEP GETSESCLEL ENHGTTDVKW HLSSLAPPYV KGVDESGDVF RATYAAFRCS 1750 1760 1770 1780 1790 1800 PISGLLESHG IQKVSITFLP RGRGDYAQFW DVECHPLKEP HMKHTLRFQL SGQSIEAENE 1810 1820 1830 1840 1850 1860 PENACLSTDS LIKIDHLVKP RRQAVSEASA RIPEQLDVTA RGVYAPEDVY RFRPTSVGES 1870 1880 1890 1900 1910 1920 RTLKVNLRNN SFITHSLKFL SPREPFYVKH SKYSLRAQHY INMPVQFKPK SAGKFEALLV 1930 1940 IQTDEGKSIA IRLIGEALGK N
	Isoform 2. Checksum: 2B078D93D54C537E	FASTA	1,407	153,582
	10 20 30 40 50 60 MKTSDLVPSF GYFIRSPEKR EPIALIRKSD VSRGNLEKEM AHLNHDLYSG DLNEQSQAQL 70 80 90 100 110 120 SEGSITLQVE AVESTSQVDE NDVTLTADKG KTEDTFFMSN KPQRYKDKLP DSGDSMLRIS 130 140 150 160 170 180 TIASAIAEAS VNTDPSQLAA MIKALSNKTR DKTFQEDEKQ KDYSHVRHFL PNDLEKSNGS 190 200 210 220 230 240 NALDMEKYLK KTEVSRYESA LENFSRASMS DTWDLSLPKE QTTQDIHPVD LSATSVSVRA 250 260 270 280 290 300 PEENTAAIVY VENGESENQE SFRTINSSNS VTNRENNSAV VDVKTCSIDN KLQDVGNDEK 310 320 330 340 350 360 ATSISTPSDS YSSVRNPRIT SLCLLKDCEE IRDNRENQRQ NECVSEISNS EKHVTFENHR 370 380 390 400 410 420 IVSPKNSDLK NTSPEHGGRG SEDEQESFRP STSPLSHSSP SEISGTSSSG CALESFGSAA 430 440 450 460 470 480 QQQQPPCEQE LSPLVCSPAG VSRLTYVSEP ESSYPTTATD DALEDRKSDI TSELSTTIIQ 490 500 510 520 530 540 GSPAALEERA MEKLREKVPF QNRGKGTLSS IIQNNSDTRK ATETTSLSSK PEYVKPDFRW 550 560 570 580 590 600 SKDPSSKSGN LLETSEVGWT SNPEELDPIR LALLGKSGLS CQVGSATSHP VSCQEPIDED 610 620 630 640 650 660 QRISPKDKST AGREFSGQVS HQTTSENQCT PIPSSTVHSS VADMQNMPAA VHALLTQPSL 670 680 690 700 710 720 SAAPFAQRYL GTLPSTGSTT LPQCHAGNAT VCGFSGGLPY PAVAGEPVQN SVAVGICLGS 730 740 750 760 770 780 NIGSGWMGTS SLCNPYSNTL NQNLLSTTKP FPVPSVGTNC GIEPWDSGVT SGLGSVRVPE 790 800 810 820 830 840 ELKLPHACCV GIASQTLLSV LNPTDRWLQV SIGVLSISVN GEKVDLSTYR CLVFKNKAII 850 860 870 880 890 900 RPHATEEIKV LFIPSSPGVF RCTFSVASWP CSTDAETIVQ AEALASTVTL TAIAESPVIE 910 920 930 940 950 960 VETEKKDVLD FGDLTYGGWK ALPLKLINRT HATVPIRLII NANAVAWRCF TFSKESVRAP 970 980 990 1000 1010 1020 VEVAPCADVV TRLAGPSVVN HMMPASYDGQ DPEFLMIWVL FHSPKKQISS SDILDSAEEF 1030 1040 1050 1060 1070 1080 SAKVDIEVDS PNPTPVLRSV SLRARAGIAR IHAPRDLQTM HFLAKVASSR KQHLPLKNAG 1090 1100 1110 1120 1130 1140 NIEVYLDIKV PEQGSHFSVD PKNLLLKPGE EHEVIVSFTP KDPEACEERI LKIFVQPFGP 1150 1160 1170 1180 1190 1200 QYEVVLKGEV ISSGSKPLSP GPCLDIPSIL SNKQFLAWGG VPLGRTQLQK LALRNNSAST 1210 1220 1230 1240 1250 1260 TQHLRLLIRG QDQDCFQLQN TFGSEQRLTS NCEIRIHPKE DIFISVLFAP TRLSCMLARL 1270 1280 1290 1300 1310 1320 EIKQLGNRSQ PGIKFTIPLS GYGGTSNLIL EGVKKLSDSY MVTVNGLVPG KESKIVFSVR 1330 1340 1350 1360 1370 1380 NTGSRAAFVK AVGFKDSQKK VLLDPKVLRI FPDKFVLKER TQENVTLIYN PSDRGINNKT 1390 1400 ATELSTVYLF GGDEISRQQY RRQGPAT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of human chromosome 18." Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J. , Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H., O'Leary S.B., Piqani B., Smith C.L., Talamas J.A., Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q., Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S. Nature 437:551-555(2005) [PubMed: 16177791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." Wiemann S., Weil B., Wellenreuther R., Gassenhuber J., Glassl S., Ansorge W., Boecher M., Bloecker H., Bauersachs S., Blum H., Lauber J., Duesterhoeft A., Beyer A., Koehrer K., Strack N., Mewes H.-W., Ottenwaelder B., Obermaier B. , Tampe J., Heubner D., Wambutt R., Korn B., Klein M., Poustka A. Genome Res. 11:422-435(2001) [PubMed: 11230166] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 161-1941 (ISOFORM 1), VARIANTS MET-769; HIS-948; PRO-956; PHE-1105; PRO-1525 AND LEU-1853. Tissue: Testis.
[3]	"Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones." Jikuya H., Takano J., Kikuno R., Hirosawa M., Nagase T., Nomura N., Ohara O. DNA Res. 10:49-57(2003) [PubMed: 12693554] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 201-1941 (ISOFORM 1), VARIANTS PRO-956; PHE-1105; ASN-1455; PRO-1525; GLU-1675 AND LEU-1853. Tissue: Spleen.
[4]	"Large-scale cDNA transfection screening for genes related to cancer development and progression." Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X. , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J. Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed: 15498874] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 857-1941 (ISOFORM 2), VARIANTS HIS-948; PRO-956 AND PHE-1105.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1362-1941 (ISOFORM 1), VARIANTS PRO-1525 AND LEU-1853.
[6]	"Proteomic characterization of the human centrosome by protein correlation profiling." Andersen J.S., Wilkinson C.J., Mayor T., Mortensen P., Nigg E.A., Mann M. Nature 426:570-574(2003) [PubMed: 14654843] [Abstract] Cited for: SUBCELLULAR LOCATION, MASS SPECTROMETRY. Tissue: Brain.
[7]	"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin." Pope S.N., Lee I.R. J. Steroid Biochem. Mol. Biol. 94:203-208(2005) [PubMed: 15862967] [Abstract] Cited for: INTERACTION WITH SHBG.
[8]	"Phosphoproteome analysis of the human mitotic spindle." Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R. Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) [PubMed: 16565220] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1155 AND SER-1159, MASS SPECTROMETRY. Tissue: Epithelium.
[9]	"Human Cep192 is required for mitotic centrosome and spindle assembly." Gomez-Ferreria M.A., Rath U., Buster D.W., Chanda S.K., Caldwell J.S., Rines D.R., Sharp D.J. Curr. Biol. 17:1960-1966(2007) [PubMed: 17980596] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[10]	"The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis." Zhu F., Lawo S., Bird A., Pinchev D., Ralph A., Richter C., Mueller-Reichert T., Kittler R., Hyman A.A., Pelletier L. Curr. Biol. 18:136-141(2008) [PubMed: 18207742] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[11]	"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S. Anal. Chem. 81:4493-4501(2009) [PubMed: 19413330] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1514, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP001357 Genomic DNA. No translation available. AP002449 Genomic DNA. No translation available. AL136818 mRNA. Translation: CAB66752.1. Sequence problems. AK074074 mRNA. Translation: BAB84900.1. AF318363 mRNA. Translation: AAL55870.1. Different initiation. AK001214 mRNA. Translation: BAA91559.1. Different initiation.
IPI	IPI00456708. IPI00940639.
UniGene	Hs.100914
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8TEP8. 1 interaction.
STRING	Q8TEP8.
PTM databases
PhosphoSite	Q8TEP8.
Proteomic databases
PeptideAtlas	Q8TEP8.
PRIDE	Q8TEP8.
Genome annotation databases
Ensembl	ENST00000325971; ENSP00000317156; ENSG00000101639; Homo sapiens. [Genome view]
KEGG	hsa:55125.
NMPDR	fig|9606.3.peg.14815.
UCSC	uc002krt.1. human.
Organism-specific databases
GeneCards	GC18P012998.
HGNC	HGNC:25515. CEP192.
PharmGKB	PA142672129.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q8TEP8.
OMA	SMFPWSG
OrthoDB	EOG9V45T7
Enzyme and pathway databases
Reactome	REACT_152. Cell Cycle, Mitotic.
Gene expression databases
ArrayExpress	Q8TEP8.
Bgee	Q8TEP8.
CleanEx	HS_CEP192.
Genevestigator	Q8TEP8.
Family and domain databases
InterPro	IPR008962. PapD-like. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	58782.

Entry information

Entry name

CE192_HUMAN

Accession

Primary (citable) accession number: Q8TEP8
Secondary accession number(s): Q8WYT8, Q9H0F4, Q9NW27

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	November 24, 2009
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.