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Reviewed, UniProtKB/Swiss-Prot Q8TEM1 (PO210_HUMAN)

Last modified February 9, 2010. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Nuclear pore membrane glycoprotein 210
      Short name=Nuclear pore protein gp210
Alternative name(s):
    Nuclear envelope pore membrane protein POM 210
      Short name=POM210
    Pore membrane protein of 210 kDa
    Nucleoporin Nup210
Gene names
Name: NUP210
Synonyms: KIAA0906
ORF Names: PSEC0245
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length1887 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Ref.8

Subunit structure

Forms dimers and possibly higher-order oligomers By similarity.

Subcellular location

Nucleus › nuclear pore complex. Nucleus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein Ref.7.

Tissue specificity

Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. Ref.4

Post-translational modification

N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides By similarity. Ref.12

Phosphorylated at Ser-1881 in mitosis specifically; not phosphorylated in interphase By similarity. Ref.9 Ref.10 Ref.14

Miscellaneous

Recognized by antinuclear autoantibodies in primary biliary cirrhosis.

Knockdown of NUP210 causes nuclear membranes to accumulate aberrant structures termed twinned and fusion-arrested membranes and nuclear pore complex to cluster. Induces cell death and chromatin disruptions.

Sequence similarities

Belongs to the NUP210 family.

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

EXOSC5Q9NQT41EBI-372826,EBI-371876

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Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q8TEM1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q8TEM1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     947-967: HPLLPGSSTIMIHDLCLVFPA → SLGHRSPLLVFIPYLGCCVVN
     968-1887: Missing.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2626 By similarity
Chain27 – 18871861Nuclear pore membrane glycoprotein 210
PRO_0000236046

Regions

Topological domain27 – 18081782Lumenal Probable
Transmembrane1809 – 182921 Potential
Topological domain1830 – 188758Cytoplasmic Probable
Compositional bias486 – 4916Poly-Ser

Amino acid modifications

Modified residue18441Phosphothreonine Ref.9 Ref.10
Modified residue18741Phosphoserine Ref.10 Ref.14
Modified residue18771Phosphoserine Ref.14
Modified residue18811Phosphoserine Ref.10 Ref.14
Modified residue18861Phosphoserine Ref.10
Glycosylation441N-linked (GlcNAc...) Potential
Glycosylation3371N-linked (GlcNAc...) Potential
Glycosylation4051N-linked (GlcNAc...) Ref.12
Glycosylation4841N-linked (GlcNAc...) Potential
Glycosylation6811N-linked (GlcNAc...) Potential
Glycosylation8011N-linked (GlcNAc...) Potential
Glycosylation9261N-linked (GlcNAc...) Ref.12
Glycosylation10391N-linked (GlcNAc...) Potential
Glycosylation11161N-linked (GlcNAc...) Potential
Glycosylation11351N-linked (GlcNAc...) Potential
Glycosylation13621N-linked (GlcNAc...) Potential
Glycosylation14411N-linked (GlcNAc...) Ref.12

Natural variations

Alternative sequence947 – 96721HPLLP…LVFPA → SLGHRSPLLVFIPYLGCCVV N in isoform 2.
VSP_018567
Alternative sequence968 – 1887920Missing in isoform 2.
VSP_018568
Natural variant2971A → T: dbSNP rs7628051.
VAR_028147
Natural variant6081I → V: dbSNP rs3732671.
VAR_028148
Natural variant7551A → V: dbSNP rs6795271.
VAR_028149
Natural variant7861R → L: dbSNP rs2280084. Ref.3
VAR_026474
Natural variant8211P → A: dbSNP rs2280085.
VAR_028150
Natural variant9441A → P: dbSNP rs433032.
VAR_028151
Natural variant10961M → I: dbSNP rs2271505.
VAR_028152
Natural variant14301D → E: dbSNP rs13081937.
VAR_028153
Natural variant17521L → S: dbSNP rs354479. Ref.4 Ref.5 Ref.6
VAR_026475
Natural variant17871V → M: dbSNP rs354478. Ref.4 Ref.5 Ref.6
VAR_026476

Experimental info

Sequence conflict15121A → T in BAC11688. Ref.5
Sequence conflict17611P → S in BAC11688. Ref.5

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Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified October 17, 2006. Version 3.
Checksum: 70B5C35E685C8DF8

FASTA1,887205,111
        10         20         30         40         50         60 
MAARGRGLLL LTLSVLLAAG PSAAAAKLNI PKVLLPFTRA TRVNFTLEAS EGCYRWLSTR 

        70         80         90        100        110        120 
PEVASIEPLG LDEQQCSQKA VVQARLTQPA RLTSIIFAED ITTGQVLRCD AIVDLIHDIQ 

       130        140        150        160        170        180 
IVSTTRELYL EDSPLELKIQ ALDSEGNTFS TLAGLVFEWT IVKDSEADRF SDSHNALRIL 

       190        200        210        220        230        240 
TFLESTYIPP SYISEMEKAA KQGDTILVSG MKTGSSKLKA RIQEAVYKNV RPAEVRLLIL 

       250        260        270        280        290        300 
ENILLNPAYD VYLMVGTSIH YKVQKIRQGK ITELSMPSDQ YELQLQNSIP GPEGDPARPV 

       310        320        330        340        350        360 
AVLAQDTSMV TALQLGQSSL VLGHRSIRMQ GASRLPNSTI YVVEPGYLGF TVHPGDRWVL 

       370        380        390        400        410        420 
ETGRLYEITI EVFDKFSNKV YVSDNIRIET VLPAEFFEVL SSSQNGSYHR IRALKRGQTA 

       430        440        450        460        470        480 
IDAALTSVVD QDGGVHILQV PVWNQQEVEI HIPITLYPSI LTFPWQPKTG AYQYTIRAHG 

       490        500        510        520        530        540 
GSGNFSWSSS SHLVATVTVK GVMTTGSDIG FSVIQAHDVQ NPLHFGEMKV YVIEPHSMEF 

       550        560        570        580        590        600 
APCQVEARVG QALELPLRIS GLMPGGASEV VTLSDCSHFD LAVEVENQGV FQPLPGRLPP 

       610        620        630        640        650        660 
GSEHCSGIRV KAEAQGSTTL LVSYRHGHVH LSAKITIAAY LPLKAVDPSS VALVTLGSSK 

       670        680        690        700        710        720 
EMLFEGGPRP WILEPSKFFQ NVTAEDTDSI GLALFAPHSS RNYQQHWILV TCQALGEQVI 

       730        740        750        760        770        780 
ALSVGNKPSL TNPFPAVEPA VVKFVCAPPS RLTLAPVYTS PQLDMSCPLL QQNKQVVPVS 

       790        800        810        820        830        840 
SHRNPRLDLA AYDQEGRRFD NFSSLSIQWE STRPVLASIE PELPMQLVSQ DDESGQKKLH 

       850        860        870        880        890        900 
GLQAILVHEA SGTTAITATA TGYQESHLSS ARTKQPHDPL VPLSASIELI LVEDVRVSPE 

       910        920        930        940        950        960 
EVTIYNHPGI QAELRIREGS GYFFLNTSTA DVVKVAYQEA RGVAMVHPLL PGSSTIMIHD 

       970        980        990       1000       1010       1020 
LCLVFPAPAK AVVYVSDIQE LYIRVVDKVE IGKTVKAYVR VLDLHKKPFL AKYFPFMDLK 

      1030       1040       1050       1060       1070       1080 
LRAASPIITL VALDEALDNY TITFLIRGVA IGQTSLTASV TNKAGQRINS APQQIEVFPP 

      1090       1100       1110       1120       1130       1140 
FRLMPRKVTL LIGATMQVTS EGGPQPQSNI LFSISNESVA LVSAAGLVQG LAIGNGTVSG 

      1150       1160       1170       1180       1190       1200 
LVQAVDAETG KVVIISQDLV QVEVLLLRAV RIRAPIMRMR TGTQMPIYVT GITNHQNPFS 

      1210       1220       1230       1240       1250       1260 
FGNAVPGLTF HWSVTKRDVL DLRGRHHEAS IRLPSQYNFA MNVLGRVKGR TGLRVVVKAV 

      1270       1280       1290       1300       1310       1320 
DPTSGQLYGL ARELSDEIQV QVFEKLQLLN PEIEAEQILM SPNSYIKLQT NRDGAASLSY 

      1330       1340       1350       1360       1370       1380 
RVLDGPEKVP VVHVDEKGFL ASGSMIGTST IEVIAQEPFG ANQTIIVAVK VSPVSYLRVS 

      1390       1400       1410       1420       1430       1440 
MSPVLHTQNK EALVAVPLGM TVTFTVHFHD NSGDVFHAHS SVLNFATNRD DFVQIGKGPT 

      1450       1460       1470       1480       1490       1500 
NNTCVVRTVS VGLTLLRVWD AEHPGLSDFM PLPVLQAISP ELSGAMVVGD VLCLATVLTS 

      1510       1520       1530       1540       1550       1560 
LEGLSGTWSS SANSILHIDP KTGVAVARAV GSVTVYYEVA GHLRTYKEVV VSVPQRIMAR 

      1570       1580       1590       1600       1610       1620 
HLHPIQTSFQ EATASKVIVA VGDRSSNLRG ECTPTQREVI QALHPETLIS CQSQFKPAVF 

      1630       1640       1650       1660       1670       1680 
DFPSQDVFTV EPQFDTALGQ YFCSITMHRL TDKQRKHLSM KKTALVVSAS LSSSHFSTEQ 

      1690       1700       1710       1720       1730       1740 
VGAEVPFSPG LFADQAEILL SNHYTSSEIR VFGAPEVLEN LEVKSGSPAV LAFAKEKSFG 

      1750       1760       1770       1780       1790       1800 
WPSFITYTVG VLDPAAGSQG PLSTTLTFSS PVTNQAIAIP VTVAFVVDRR GPGPYGASLF 

      1810       1820       1830       1840       1850       1860 
QHFLDSYQVM FFTLFALLAG TAVMIIAYHT VCTPRDLAVP AALTPRASPG HSPHYFAASS 

      1870       1880 
PTSPNALPPA RKASPPSGLW SPAYASH

« Hide

Isoform 2.

Checksum: 56A41738E2C8DEF1
Show »

FASTA967105,810

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References

« Hide 'large scale' references
[1]"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J. expand/collapse author list , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
Nature 440:1194-1198(2006) [PubMed: 16641997] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
Tissue: Spleen.
[3]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 763-1887 (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 412-1887 (ISOFORM 2), VARIANT LEU-786.
Tissue: Brain and Spleen.
[4]"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Ishikawa K., Suyama M., Kikuno R., Hirosawa M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
DNA Res. 5:355-364(1998) [PubMed: 10048485] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 965-1887 (ISOFORM 1), VARIANTS SER-1752 AND MET-1787, TISSUE SPECIFICITY.
Tissue: Brain.
[5]"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y. expand/collapse author list , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
DNA Res. 12:117-126(2005) [PubMed: 16303743] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1405-1887 (ISOFORM 1), VARIANTS SER-1752 AND MET-1787.
Tissue: Ovary tumor.
[6]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1460-1887 (ISOFORM 1), VARIANTS SER-1752 AND MET-1787.
Tissue: Testis.
[7]"The 210-kD nuclear envelope polypeptide recognized by human autoantibodies in primary biliary cirrhosis is the major glycoprotein of the nuclear pore."
Courvalin J.-C., Lassoued K., Bartnik E., Blobel G., Wozniak R.W.
J. Clin. Invest. 86:279-285(1990) [PubMed: 2195063] [Abstract]
Cited for: SUBCELLULAR LOCATION.
Tissue: Cervix carcinoma.
[8]"Nuclear pore protein gp210 is essential for viability in HeLa cells and Caenorhabditis elegans."
Cohen M., Feinstein N., Wilson K.L., Gruenbaum Y.
Mol. Biol. Cell 14:4230-4237(2003) [PubMed: 14517331] [Abstract]
Cited for: FUNCTION.
Tissue: Cervix carcinoma.
[9]"Phosphoproteome analysis of the human mitotic spindle."
Nousiainen M., Sillje H.H.W., Sauer G., Nigg E.A., Koerner R.
Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) [PubMed: 16565220] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1844, MASS SPECTROMETRY.
Tissue: Epithelium.
[10]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed: 18669648] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1844; SER-1874; SER-1881 AND SER-1886, MASS SPECTROMETRY.
[11]Colinge J., Superti-Furga G., Bennett K.L.
Submitted (OCT-2008) to UniProtKB
Cited for: IDENTIFICATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[12]"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R., Jiang X., Sun D., Han G., Wang F., Ye M., Wang L., Zou H.
J. Proteome Res. 8:651-661(2009) [PubMed: 19159218] [Abstract]
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-405; ASN-926 AND ASN-1441, MASS SPECTROMETRY.
Tissue: Liver.
[13]"Large-scale proteomics analysis of the human kinome."
Oppermann F.S., Gnad F., Olsen J.V., Hornberger R., Greff Z., Keri G., Mann M., Daub H.
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed: 19369195] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1844, MASS SPECTROMETRY.
[14]"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
Sci. Signal. 2:RA46-RA46(2009) [PubMed: 19690332] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1874; SER-1877 AND SER-1881, MASS SPECTROMETRY.
Tissue: T-cell.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC027124 Genomic DNA. No translation available.
AC069246 Genomic DNA. No translation available.
BC067089 mRNA. Translation: AAH67089.1.
AK026042 mRNA. Translation: BAB15332.1. Different initiation.
AK074101 mRNA. Translation: BAB84927.1.
AB020713 mRNA. Translation: BAA74929.1.
AK075545 mRNA. Translation: BAC11688.1. Different initiation.
AL117527 mRNA. Translation: CAB55979.2.
IPIIPI00291755.
IPI00871723.
PIRT17289.
RefSeqNP_079199.2.
UniGeneHs.475525

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ8TEM1. 1 interaction.
STRINGQ8TEM1.

PTM databases

PhosphoSiteQ8TEM1.

Proteomic databases

PRIDEQ8TEM1.

Genome annotation databases

EnsemblENST00000254508; ENSP00000254508; ENSG00000132182; Homo sapiens. [Genome view]
GeneID23225.
KEGGhsa:23225.
UCSCuc003bxv.1. human.

Organism-specific databases

CTD23225.
GeneCardsGC03M013332.
H-InvDBHIX0003074.
HGNCHGNC:30052. NUP210.
MIM607703. gene.
PharmGKBPA128394614.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG10757.
HOVERGENQ8TEM1.
InParanoidQ8TEM1.
OMADSHNALR.
OrthoDBEOG9962B6.

Enzyme and pathway databases

ReactomeREACT_6185. HIV Infection.

Gene expression databases

ArrayExpressQ8TEM1.
BgeeQ8TEM1.
CleanExHS_NUP210.
GenevestigatorQ8TEM1.
GermOnlineENSG00000132182. Homo sapiens.

Family and domain databases

InterProIPR003343. Big_2.
IPR008964. Invasin/intimin_cell_adhesion.
[Graphical view]
PfamPF02368. Big_2. 1 hit.
[Graphical view]
SMARTSM00635. BID_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio44833.
SOURCESearch...

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Entry information

Entry namePO210_HUMAN
AccessionPrimary (citable) accession number: Q8TEM1
Secondary accession number(s): A6NN56 expand/collapse secondary AC list , O94980, Q6NXG6, Q8NBJ1, Q9H6C8, Q9UFP3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 17, 2006
Last modified: February 9, 2010
This is version 59 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Relevant documents

Human chromosome 3

Human chromosome 3: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents