Q8TEF2 (CJ105_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C10orf105

Gene names

Name:

C10orf105

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	Uncharacterized protein C10orf105		PRO_0000331530
Regions
	Transmembrane	36 – 56	21	Helical; Potential
Experimental info
	Sequence conflict	54	1	L → V in BAB84998. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q8TEF2 [UniParc]. Last modified May 5, 2009. Version 3. Checksum: 9B74E1A2A20A86AE	FASTA	133	14,519
	10 20 30 40 50 60 MSTEGPSLAS SPAISPLAFL SAPVTPGTLA EATDPLPMLI ALACIFLLLA TCLLFMTLCK 70 80 90 100 110 120 PAALDPSRRR AHECMPHHPG SPSEPQLRLW KRLGSLRLSL HSFRHGRPTV PRQPLPGPED 130 NRSHCDYMES TKM

References

[1]	"The nucleotide sequence of a long cDNA clone isolated from human spleen." Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O. Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Spleen.
[2]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed: 15164054] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK074172 mRNA. Translation: BAB84998.1. AL731541 Genomic DNA. No translation available. BC071608 mRNA. No translation available.
IPI	IPI00887665.
RefSeq	NP_001157847.1. NM_001164375.2. NP_001161862.1. NM_001168390.1.
UniGene	Hs.568788.
3D structure databases
ProteinModelPortal	Q8TEF2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000398786; ENSP00000381766; ENSG00000214688. ENST00000441508; ENSP00000403151; ENSG00000214688.
GeneID	414152.
KEGG	hsa:414152.
UCSC	uc001jsa.1. human.
Organism-specific databases
CTD	414152.
GeneCards	GC10M073472.
HGNC	HGNC:20304. C10orf105.
neXtProt	NX_Q8TEF2.
PharmGKB	PA134923659.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00490000043902.
HOVERGEN	HBG107695.
InParanoid	Q8TEF2.
OrthoDB	EOG4R23W6.
Gene expression databases
ArrayExpress	Q8TEF2.
Bgee	Q8TEF2.
CleanEx	HS_C10orf105.
Genevestigator	Q8TEF2.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CJ105_HUMAN

Accession

Primary (citable) accession number: Q8TEF2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	May 5, 2009
Last modified:	January 25, 2012
This is version 44 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.