Q8TDT8 (Q8TDT8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative G-protein coupled receptor EMBL BAB89326.1

Gene names

Name:

GPCR EMBL BAB89326.1

Organism

Homo sapiens (Human) EMBL BAB89326.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 FZ (frizzled) domain. SAAS SAAS015526

Ontologies

Keywords
Biological process	Wnt signaling pathway SAAS SAAS015526
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000539
Molecular function	Developmental protein SAAS SAAS015526 G-protein coupled receptor SAAS SAAS015526 Receptor Transducer
PTM	Disulfide bond SAAS SAAS020067
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8TDT8 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 9DFECFA479CB993F	FASTA	433	48,661
	10 20 30 40 50 60 MCTEKINIPI GPCGGMCLSV KRRCEPVLKE FGFAWPESLN CSKFPPQNDH NHMCMEGPGD 70 80 90 100 110 120 EEVPLPHKTP IQPGEECHSV GTNSDQYIWV KRSLNCVLKC GYDAGLYSRS AKEFTDIWMA 130 140 150 160 170 180 VWASLCFIST AFTVLTFLID SSRFSYPERP IIFLSMCYNI YSIAYIVRLT VGRERISCDF 190 200 210 220 230 240 EEAAEPVLIQ EGLKNTGCAI IFLLMYFFGM ASSIWWVILT LTWFLAAGLK WGHEAIEMHS 250 260 270 280 290 300 SYFHIAAWAI PAVKTIVILI MRLVDADELT GLCYVGNQNL DALTGFVVAP LFTYLVIGTL 310 320 330 340 350 360 FIAAGLVALF KIRSNLQKDG TKTDKLERLM VKIGVFSVLY TVPATCVIAC YFYEISNWAL 370 380 390 400 410 420 FRYSADDSNM AVEMLKIFMS LLVGITSGMW IWSAKTLHTW QKCSNRLVNS GKVKREKRGN 430 GWVKPGKGSE TVV

References

[1]	"Identification of G protein-coupled receptor genes from the human genome sequence." Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S. FEBS Lett. 520:97-101(2002) [PubMed: 12044878] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB083613 Genomic DNA. Translation: BAB89326.1.
IPI	IPI00977659.
UniGene	Hs.591968.
3D structure databases
ProteinModelPortal	Q8TDT8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8TDT8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG006977.
Gene expression databases
ArrayExpress	Q8TDT8.
Bgee	Q8TDT8.
Family and domain databases
InterPro	IPR000539. Frizzled. IPR015526. Frizzled-related. IPR020067. Frizzled_dom. IPR017981. GPCR_2-like. [Graphical view]
Gene3D	G3DSA:1.10.2000.10. Frizzled_Cys-rich. 1 hit.
PANTHER	PTHR11309. Fz_related. 1 hit.
Pfam	PF01534. Frizzled. 1 hit. PF01392. Fz. 1 hit. [Graphical view]
PRINTS	PR00489. FRIZZLED.
SUPFAM	SSF63501. Frizzled_Cys-rich. 1 hit.
PROSITE	PS50038. FZ. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8TDT8_HUMAN

Accession

Primary (citable) accession number: Q8TDT8

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.