ID   Q8TDI7      PRELIMINARY;      PRT;   890 AA.
AC   Q8TDI7;
DT   01-JUN-2002 (TrEMBLrel. 21, Created)
DT   01-JUN-2002 (TrEMBLrel. 21, Last sequence update)
DT   01-JUN-2002 (TrEMBLrel. 21, Last annotation update)
DE   Transmembrane cochlear-expressed protein 2.
GN   TMC2.
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=21918583; PubMed=11850618;
RA   Kurima K., Peters L.M., Yang Y., Riazuddin S., Ahmed Z.M., Naz S.,
RA   Arnaud D., Drury S., Mo J., Makishima T., Ghosh M., Menon P.S.N.,
RA   Deshmukh D., Oddoux C., Ostrer H., Khan S., Raizuddin S.,
RA   Deininger P.L., Hampton L.L., Sullivan S.L., Battey J.F.,
RA   Keats B.J.B., Wilcox E.R., Friedman T.B., Griffith A.J.;
RT   "Dominant and recessive deafness caused by mutations of a novel gene,
RT   TMC1, required for cochlear hair-cell function.";
RL   Nat. Genet. 30:277-284(2002).
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DR   EMBL; AF417580; AAL86401.1; -.
SQ   SEQUENCE   890 AA;  101006 MW;  A35AE2216B2AC0C4 CRC64;
     MSHQVKGLKE EGDRLGRRSS SKRALKAEGT PGRRGAQRSQ KERAGGSPSP GSPRRKQTGR
     RRHREELGEQ ERGEAERTCE GRRKRDERAS FQERTAAPKR EKEIPRKEEK SKRQKKPRSS
     SLASSASGGE SLSEEELAQI LEQVEEKKKL IATMRSKPWP MAKKLTELRE AQEFVEKYEG
     ALGKGKGKQL YAYKMLMAKK WVKFKRDFDN FKTQCIPWEM KIKDIESHFG SSVASYFIFL
     RWMYGVNLVL FGLIFGLVII PEVLMGMPYG SIPRKTVPRA EEEKAMDFSV LWDFEGYIKY
     SALFYGYYNN QRTIGWLRYR LPMAYFMVGV SVFGYSLIIV IRSMASNTQG STGEGESDNF
     TFSFKMFTSW DYLIGNSETA DNKYASITTS FKESIVDEQE SNKEENIHLT RFLRVLANFL
     IICCLCGSGY LIYFVVKRSQ QFSKMQNVSW YERNEVEIVM SLLGMFCPPL FETIAALENY
     HPRTGLKWQL GRIFALFLGN LYTFLLALMD DVHLKLANEE TIKNITHWTL FNYYNSSGWN
     ESVPRPPLHP ADVPRGSCWE TAVGIEFMRL TVSDMLVTYI TILLGDFLRA CFVRFMNYCW
     CWDLEAGFPS YAEFDISGNV LGLIFNQGMI WMGSFYAPGL VGINVLRLLT SMYFQCWAVM
     SSNVPHERVF KASRSNNFYM GLLLLVLFLS LLPVAYTIMS LPPSFDCGPF SGKNRMYDVL
     QETIENDFPT FLGKIFAFLA NPGLIIPAIL LMFLAIYYLN SVSKSLSRAN AQLRKKIQVL
     REVEKSHKSV KGKATARDSE DTPKSSSKNA TQLQLTKEET TPPSASQSQA MDKKAQGPGT
     SNSASRTTLP ASGHLPISRP PGIGPDSGHA PSQTHPWRSA SGKSAQRPPH
//