Unreviewed, UniProtKB/TrEMBL Q8TDA6 (Q8TDA6_HUMAN)

Names and origin

Protein names	Submitted name:     CTLA4 EMBL AAL96664.1
Organism	Homo sapiens (Human) EMBL AAL96664.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	160 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	immune response Inferred from electronic annotation. Source: InterPro negative regulation of T cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of immune response Inferred from electronic annotation. Source: Compara
Cellular component	external side of plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	protein binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	160	1	EMBL AAL96664.1

Sequences

	Sequence		Length	Mass (Da)
	Q8TDA6-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 1385B4644F63836F	FASTA	160	17,470
	10 20 30 40 50 60 MACLGFQRHK AQLNLATRTW PCTLLFFLLF IPVFCKAMHV AQPAVVLASS RGIASFVCEY 70 80 90 100 110 120 ASPGKATEVR VTVLRQADSQ VTEVCAATYM MGNELTFLDD SICTGTSSGN QVNLTIQGLR 130 140 150 160 AMDTGLYICK VELMYPPPYY LGIGNGTQIY VIDPEPCPDS

References

[1]	"Partial sequence of CTLA4 mRNA, signal peptide and extracellular domain." Guo J.H., Fan M.W., Bian Z., Jia R. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF486806 mRNA. Translation: AAL96664.1.
IPI	IPI00028559.
PIR	I84732.
UniGene	Hs.247824
3D structure databases
HSSP	HSSP built from PDB template 1AH1 based on UniProtKB P16410.
SMR	Q8TDA6. Positions 37-160.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8TDA6.
Genome annotation databases
Ensembl	ENST00000302823; ENSP00000303939; ENSG00000163599; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:2505. CTLA4.
Phylogenomic databases
HOVERGEN	Q8TDA6.
Gene expression databases
ArrayExpress	Q8TDA6.
Bgee	Q8TDA6.
Family and domain databases
InterPro	IPR008096. CTLA4. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_sub. [Graphical view]
Gene3D	G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF07686. V-set. 1 hit. [Graphical view]
PRINTS	PR01720. CTLANTIGEN4.
SMART	SM00406. IGv. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8TDA6_HUMAN

Accession

Primary (citable) accession number: Q8TDA6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 19, 2010
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.