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Protein
Submitted name:

Prothrombin

Gene

F2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ProthrombinImported (EC:3.4.21.5Imported)
Gene namesi
Name:F2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ8TD58.
PRIDEiQ8TD58.

Expressioni

Gene expression databases

BgeeiQ8TD58.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000308541.

Structurei

3D structure databases

ProteinModelPortaliQ8TD58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 3834Peptidase S1InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IKPN. Eukaryota.
COG5640. LUCA.

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
IPR003966. Prothrombin/thrombin.
IPR001254. Trypsin_dom.
[Graphical view]
PANTHERiPTHR24254:SF10. PTHR24254:SF10. 1 hit.
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8TD58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
SPFNNRWYQM GIVSWGEGCD RDGKYGFYTH VFRLKKWIQK VIDQFGE
Length:47
Mass (Da):5,688
Last modified:June 1, 2002 - v1
Checksum:i9B5E9995F808DC4B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF493953 Genomic DNA. Translation: AAM11680.1.
UniGeneiHs.655207.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF493953 Genomic DNA. Translation: AAM11680.1.
UniGeneiHs.655207.

3D structure databases

ProteinModelPortaliQ8TD58.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000308541.

Proteomic databases

PaxDbiQ8TD58.
PRIDEiQ8TD58.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IKPN. Eukaryota.
COG5640. LUCA.

Gene expression databases

BgeeiQ8TD58.

Family and domain databases

InterProiIPR009003. Peptidase_S1_PA.
IPR003966. Prothrombin/thrombin.
IPR001254. Trypsin_dom.
[Graphical view]
PANTHERiPTHR24254:SF10. PTHR24254:SF10. 1 hit.
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Prothrombin gene expression and mRNA stability."
    Hehlgans S.I., Weiss B., Zeyer A., Doehner U., Mueller-Berghaus G., Poetzsch B., von der Ahe D.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BloodImported.

Entry informationi

Entry nameiQ8TD58_HUMAN
AccessioniPrimary (citable) accession number: Q8TD58
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: June 8, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.