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Protein
Submitted name:

Prothrombin

Gene

F2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
ProthrombinImported (EC:3.4.21.5Imported)
Gene namesi
Name:F2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ8TD58.
PeptideAtlasiQ8TD58.
PRIDEiQ8TD58.

Expressioni

Gene expression databases

BgeeiENSG00000180210.

Structurei

3D structure databases

ProteinModelPortaliQ8TD58.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 38Peptidase S1InterPro annotationAdd BLAST33

Phylogenomic databases

eggNOGiENOG410IKPN. Eukaryota.
COG5640. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR003966. Prothrombin/thrombin.
IPR001254. Trypsin_dom.
PANTHERiPTHR24254:SF13. PTHR24254:SF13. 1 hit.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q8TD58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
SPFNNRWYQM GIVSWGEGCD RDGKYGFYTH VFRLKKWIQK VIDQFGE
Length:47
Mass (Da):5,688
Last modified:June 1, 2002 - v1
Checksum:i9B5E9995F808DC4B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF493953 Genomic DNA. Translation: AAM11680.1.
UniGeneiHs.655207.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ8TD58_HUMAN
AccessioniPrimary (citable) accession number: Q8TD58
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: July 5, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.