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Q8TD47

- RS4Y2_HUMAN

UniProt

Q8TD47 - RS4Y2_HUMAN

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Protein

40S ribosomal protein S4, Y isoform 2

Gene
RPS4Y2, RPS4Y2P
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-KW
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4, Y isoform 2
Gene namesi
Name:RPS4Y2
Synonyms:RPS4Y2P
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome Y

Organism-specific databases

HGNCiHGNC:18501. RPS4Y2.

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38563.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 26326340S ribosomal protein S4, Y isoform 2UniRule annotationPRO_0000130818Add
BLAST

Proteomic databases

MaxQBiQ8TD47.
PaxDbiQ8TD47.
PRIDEiQ8TD47.

PTM databases

PhosphoSiteiQ8TD47.

Expressioni

Gene expression databases

BgeeiQ8TD47.
GenevestigatoriQ8TD47.

Organism-specific databases

HPAiHPA000857.

Interactioni

Protein-protein interaction databases

BioGridi126595. 1 interaction.
STRINGi9606.ENSP00000288666.

Structurei

3D structure databases

ProteinModelPortaliQ8TD47.
SMRiQ8TD47. Positions 1-263.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini42 – 10463S4 RNA-bindingAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1471.
HOGENOMiHOG000231325.
HOVERGENiHBG000935.
InParanoidiQ8TD47.
OMAiERHPGSC.
OrthoDBiEOG77WWD1.
PhylomeDBiQ8TD47.
TreeFamiTF300612.

Family and domain databases

HAMAPiMF_00485. Ribosomal_S4e.
InterProiIPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiPF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
[Graphical view]
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00739. KOW. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8TD47-1 [UniParc]FASTAAdd to Basket

« Hide

MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIVFLRN    50
RLKYALTGDE VKKICMQHFL KIDGKVRVDI TYPAGFIDVI SIEKTGEHFR 100
LVYNTKGCFA VHRITVEEAK YKLCKVRKIT VGTKGIPHLV THDARTIRYP 150
DPLIKVNDTV QIDLGTGKIT SFIKFDTGNV CMVIAGANLG RVGVITNRER 200
HPGSCDVVHV KDANGNSFAT RISNIFVIGN GNKPWISLPR GKGIRLTIAE 250
ERDKRLAAKQ SSG 263
Length:263
Mass (Da):29,295
Last modified:January 23, 2007 - v3
Checksum:i7044C5C97361E3D0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC009494 Genomic DNA. No translation available.
AF497481 mRNA. Translation: AAM18074.1.
CCDSiCCDS44028.1.
RefSeqiNP_001034656.1. NM_001039567.2.
UniGeneiHs.367761.

Genome annotation databases

EnsembliENST00000288666; ENSP00000288666; ENSG00000157828.
GeneIDi140032.
KEGGihsa:140032.
UCSCiuc011nbb.2. human.

Polymorphism databases

DMDMi27805713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC009494 Genomic DNA. No translation available.
AF497481 mRNA. Translation: AAM18074.1 .
CCDSi CCDS44028.1.
RefSeqi NP_001034656.1. NM_001039567.2.
UniGenei Hs.367761.

3D structure databases

ProteinModelPortali Q8TD47.
SMRi Q8TD47. Positions 1-263.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 126595. 1 interaction.
STRINGi 9606.ENSP00000288666.

PTM databases

PhosphoSitei Q8TD47.

Polymorphism databases

DMDMi 27805713.

Proteomic databases

MaxQBi Q8TD47.
PaxDbi Q8TD47.
PRIDEi Q8TD47.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000288666 ; ENSP00000288666 ; ENSG00000157828 .
GeneIDi 140032.
KEGGi hsa:140032.
UCSCi uc011nbb.2. human.

Organism-specific databases

CTDi 140032.
GeneCardsi GC0YP022917.
GeneReviewsi RPS4Y2.
HGNCi HGNC:18501. RPS4Y2.
HPAi HPA000857.
MIMi 400030. gene.
neXtProti NX_Q8TD47.
PharmGKBi PA38563.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG1471.
HOGENOMi HOG000231325.
HOVERGENi HBG000935.
InParanoidi Q8TD47.
OMAi ERHPGSC.
OrthoDBi EOG77WWD1.
PhylomeDBi Q8TD47.
TreeFami TF300612.

Miscellaneous databases

GenomeRNAii 140032.
NextBioi 84063.
PROi Q8TD47.
SOURCEi Search...

Gene expression databases

Bgeei Q8TD47.
Genevestigatori Q8TD47.

Family and domain databases

HAMAPi MF_00485. Ribosomal_S4e.
InterProi IPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view ]
PANTHERi PTHR11581. PTHR11581. 1 hit.
Pfami PF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
[Graphical view ]
PIRSFi PIRSF002116. Ribosomal_S4. 1 hit.
ProDomi PD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00739. KOW. 1 hit.
SM00363. S4. 1 hit.
[Graphical view ]
PROSITEi PS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA / MRNA].

Entry informationi

Entry nameiRS4Y2_HUMAN
AccessioniPrimary (citable) accession number: Q8TD47
Secondary accession number(s): A6NIR6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome Y
    Human chromosome Y: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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