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Q8TD47

- RS4Y2_HUMAN

UniProt

Q8TD47 - RS4Y2_HUMAN

Protein

40S ribosomal protein S4, Y isoform 2

Gene

RPS4Y2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S4, Y isoform 2
    Gene namesi
    Name:RPS4Y2
    Synonyms:RPS4Y2P
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome Y

    Organism-specific databases

    HGNCiHGNC:18501. RPS4Y2.

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38563.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 26326340S ribosomal protein S4, Y isoform 2PRO_0000130818Add
    BLAST

    Proteomic databases

    MaxQBiQ8TD47.
    PaxDbiQ8TD47.
    PRIDEiQ8TD47.

    PTM databases

    PhosphoSiteiQ8TD47.

    Expressioni

    Gene expression databases

    BgeeiQ8TD47.
    GenevestigatoriQ8TD47.

    Organism-specific databases

    HPAiHPA000857.

    Interactioni

    Protein-protein interaction databases

    BioGridi126595. 1 interaction.
    STRINGi9606.ENSP00000288666.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TD47.
    SMRiQ8TD47. Positions 1-263.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini42 – 10463S4 RNA-bindingAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein S4e family.Curated
    Contains 1 S4 RNA-binding domain.Curated

    Phylogenomic databases

    eggNOGiCOG1471.
    HOGENOMiHOG000231325.
    HOVERGENiHBG000935.
    InParanoidiQ8TD47.
    OMAiERHPGSC.
    OrthoDBiEOG77WWD1.
    PhylomeDBiQ8TD47.
    TreeFamiTF300612.

    Family and domain databases

    HAMAPiMF_00485. Ribosomal_S4e.
    InterProiIPR005824. KOW.
    IPR000876. Ribosomal_S4e.
    IPR013845. Ribosomal_S4e_central_region.
    IPR013843. Ribosomal_S4e_N.
    IPR018199. Ribosomal_S4e_N_CS.
    IPR002942. S4_RNA-bd.
    [Graphical view]
    PANTHERiPTHR11581. PTHR11581. 1 hit.
    PfamiPF00467. KOW. 1 hit.
    PF00900. Ribosomal_S4e. 1 hit.
    PF08071. RS4NT. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
    ProDomiPD002667. Ribosomal_S4e_central. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00739. KOW. 1 hit.
    SM00363. S4. 1 hit.
    [Graphical view]
    PROSITEiPS00528. RIBOSOMAL_S4E. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8TD47-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIVFLRN    50
    RLKYALTGDE VKKICMQHFL KIDGKVRVDI TYPAGFIDVI SIEKTGEHFR 100
    LVYNTKGCFA VHRITVEEAK YKLCKVRKIT VGTKGIPHLV THDARTIRYP 150
    DPLIKVNDTV QIDLGTGKIT SFIKFDTGNV CMVIAGANLG RVGVITNRER 200
    HPGSCDVVHV KDANGNSFAT RISNIFVIGN GNKPWISLPR GKGIRLTIAE 250
    ERDKRLAAKQ SSG 263
    Length:263
    Mass (Da):29,295
    Last modified:January 23, 2007 - v3
    Checksum:i7044C5C97361E3D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009494 Genomic DNA. No translation available.
    AF497481 mRNA. Translation: AAM18074.1.
    CCDSiCCDS44028.1.
    RefSeqiNP_001034656.1. NM_001039567.2.
    UniGeneiHs.367761.

    Genome annotation databases

    EnsembliENST00000288666; ENSP00000288666; ENSG00000157828.
    GeneIDi140032.
    KEGGihsa:140032.
    UCSCiuc011nbb.2. human.

    Polymorphism databases

    DMDMi27805713.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC009494 Genomic DNA. No translation available.
    AF497481 mRNA. Translation: AAM18074.1 .
    CCDSi CCDS44028.1.
    RefSeqi NP_001034656.1. NM_001039567.2.
    UniGenei Hs.367761.

    3D structure databases

    ProteinModelPortali Q8TD47.
    SMRi Q8TD47. Positions 1-263.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 126595. 1 interaction.
    STRINGi 9606.ENSP00000288666.

    PTM databases

    PhosphoSitei Q8TD47.

    Polymorphism databases

    DMDMi 27805713.

    Proteomic databases

    MaxQBi Q8TD47.
    PaxDbi Q8TD47.
    PRIDEi Q8TD47.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000288666 ; ENSP00000288666 ; ENSG00000157828 .
    GeneIDi 140032.
    KEGGi hsa:140032.
    UCSCi uc011nbb.2. human.

    Organism-specific databases

    CTDi 140032.
    GeneCardsi GC0YP022917.
    GeneReviewsi RPS4Y2.
    HGNCi HGNC:18501. RPS4Y2.
    HPAi HPA000857.
    MIMi 400030. gene.
    neXtProti NX_Q8TD47.
    PharmGKBi PA38563.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG1471.
    HOGENOMi HOG000231325.
    HOVERGENi HBG000935.
    InParanoidi Q8TD47.
    OMAi ERHPGSC.
    OrthoDBi EOG77WWD1.
    PhylomeDBi Q8TD47.
    TreeFami TF300612.

    Miscellaneous databases

    GenomeRNAii 140032.
    NextBioi 84063.
    PROi Q8TD47.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8TD47.
    Genevestigatori Q8TD47.

    Family and domain databases

    HAMAPi MF_00485. Ribosomal_S4e.
    InterProi IPR005824. KOW.
    IPR000876. Ribosomal_S4e.
    IPR013845. Ribosomal_S4e_central_region.
    IPR013843. Ribosomal_S4e_N.
    IPR018199. Ribosomal_S4e_N_CS.
    IPR002942. S4_RNA-bd.
    [Graphical view ]
    PANTHERi PTHR11581. PTHR11581. 1 hit.
    Pfami PF00467. KOW. 1 hit.
    PF00900. Ribosomal_S4e. 1 hit.
    PF08071. RS4NT. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002116. Ribosomal_S4. 1 hit.
    ProDomi PD002667. Ribosomal_S4e_central. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00739. KOW. 1 hit.
    SM00363. S4. 1 hit.
    [Graphical view ]
    PROSITEi PS00528. RIBOSOMAL_S4E. 1 hit.
    PS50889. S4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA / MRNA].

    Entry informationi

    Entry nameiRS4Y2_HUMAN
    AccessioniPrimary (citable) accession number: Q8TD47
    Secondary accession number(s): A6NIR6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 17, 2003
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 97 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome Y
      Human chromosome Y: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Ribosomal proteins
      Ribosomal proteins families and list of entries
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3