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Q8TD47 (RS4Y2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
40S ribosomal protein S4, Y isoform 2
Gene names
Name:RPS4Y2
Synonyms:RPS4Y2P
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ribosomal protein S4e family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 26326340S ribosomal protein S4, Y isoform 2 HAMAP-Rule MF_00485
PRO_0000130818

Regions

Domain42 – 10463S4 RNA-binding

Sequences

Sequence LengthMass (Da)Tools
Q8TD47 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 7044C5C97361E3D0

FASTA26329,295
        10         20         30         40         50         60 
MARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIVFLRN RLKYALTGDE 

        70         80         90        100        110        120 
VKKICMQHFL KIDGKVRVDI TYPAGFIDVI SIEKTGEHFR LVYNTKGCFA VHRITVEEAK 

       130        140        150        160        170        180 
YKLCKVRKIT VGTKGIPHLV THDARTIRYP DPLIKVNDTV QIDLGTGKIT SFIKFDTGNV 

       190        200        210        220        230        240 
CMVIAGANLG RVGVITNRER HPGSCDVVHV KDANGNSFAT RISNIFVIGN GNKPWISLPR 

       250        260 
GKGIRLTIAE ERDKRLAAKQ SSG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC009494 Genomic DNA. No translation available.
AF497481 mRNA. Translation: AAM18074.1.
RefSeqNP_001034656.1. NM_001039567.2.
UniGeneHs.367761.

3D structure databases

ProteinModelPortalQ8TD47.
SMRQ8TD47. Positions 1-263.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid126595. 1 interaction.
STRING9606.ENSP00000288666.

PTM databases

PhosphoSiteQ8TD47.

Polymorphism databases

DMDM27805713.

Proteomic databases

PaxDbQ8TD47.
PRIDEQ8TD47.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000288666; ENSP00000288666; ENSG00000157828.
GeneID140032.
KEGGhsa:140032.
UCSCuc011nbb.2. human.

Organism-specific databases

CTD140032.
GeneCardsGC0YP022917.
HGNCHGNC:18501. RPS4Y2.
HPAHPA000857.
MIM400030. gene.
neXtProtNX_Q8TD47.
PharmGKBPA38563.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG1471.
HOGENOMHOG000231325.
HOVERGENHBG000935.
InParanoidQ8TD47.
OMARVDITYP.
OrthoDBEOG77WWD1.
PhylomeDBQ8TD47.
TreeFamTF300612.

Gene expression databases

BgeeQ8TD47.
GenevestigatorQ8TD47.

Family and domain databases

HAMAPMF_00485. Ribosomal_S4e.
InterProIPR005824. KOW.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERPTHR11581. PTHR11581. 1 hit.
PfamPF00467. KOW. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
[Graphical view]
PIRSFPIRSF002116. Ribosomal_S4. 1 hit.
ProDomPD002667. Ribosomal_S4e_central. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00739. KOW. 1 hit.
SM00363. S4. 1 hit.
[Graphical view]
PROSITEPS00528. RIBOSOMAL_S4E. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi140032.
NextBio84063.
PROQ8TD47.
SOURCESearch...

Entry information

Entry nameRS4Y2_HUMAN
AccessionPrimary (citable) accession number: Q8TD47
Secondary accession number(s): A6NIR6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 94 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome Y

Human chromosome Y: entries, gene names and cross-references to MIM