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Q8TD33

- SG1C1_HUMAN

UniProt

Q8TD33 - SG1C1_HUMAN

Protein

Secretoglobin family 1C member 1

Gene

SCGB1C1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Secretoglobin family 1C member 1
    Alternative name(s):
    Secretoglobin RYD5
    Gene namesi
    Name:SCGB1C1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:18394. SCGB1C1.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 9572Secretoglobin family 1C member 1PRO_0000223332Add
    BLAST

    Proteomic databases

    PRIDEiQ8TD33.

    PTM databases

    PhosphoSiteiQ8TD33.

    Expressioni

    Gene expression databases

    BgeeiQ8TD33.
    CleanExiHS_SCGB1C1.
    GenevestigatoriQ8TD33.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000344545.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TD33.
    SMRiQ8TD33. Positions 25-94.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the secretoglobin family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG27764.
    HOGENOMiHOG000220914.
    HOVERGENiHBG098533.
    InParanoidiQ8TD33.
    OMAiNEFFMDF.
    OrthoDBiEOG74XS9P.
    PhylomeDBiQ8TD33.
    TreeFamiTF337061.

    Family and domain databases

    InterProiIPR016126. Secretoglobin.
    IPR028659. Secretoglobin_1C1.
    [Graphical view]
    PANTHERiPTHR10136:SF7. PTHR10136:SF7. 1 hit.
    PfamiPF01099. Uteroglobin. 1 hit.
    [Graphical view]
    SMARTiSM00096. UTG. 1 hit.
    [Graphical view]
    SUPFAMiSSF48201. SSF48201. 1 hit.
    PROSITEiPS51311. SCGB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8TD33-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL   50
    GKYNVNEDAK AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA 95
    Length:95
    Mass (Da):10,414
    Last modified:May 18, 2010 - v2
    Checksum:iF6331EADC96D2392
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti70 – 701I → R.3 Publications
    Corresponds to variant rs2686894 [ dbSNP | Ensembl ].
    VAR_063102

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY026938 mRNA. Translation: AAK08972.1.
    AC069287 Genomic DNA. No translation available.
    BC069287 mRNA. Translation: AAH69287.1.
    BC111427 mRNA. Translation: AAI11428.1.
    BC111433 mRNA. Translation: AAI11434.1.
    BK000201 mRNA. Translation: DAA00358.1.
    CCDSiCCDS41581.1.
    RefSeqiNP_001091079.1. NM_001097610.2.
    NP_663626.2. NM_145651.2.
    XP_005252861.1. XM_005252804.1.
    XP_005277990.1. XM_005277933.1.
    XP_006725313.1. XM_006725250.1.
    UniGeneiHs.127059.

    Genome annotation databases

    EnsembliENST00000342878; ENSP00000344545; ENSG00000188076.
    GeneIDi147199.
    653486.
    KEGGihsa:147199.
    hsa:653486.
    UCSCiuc001loa.1. human.

    Polymorphism databases

    DMDMi296452904.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY026938 mRNA. Translation: AAK08972.1 .
    AC069287 Genomic DNA. No translation available.
    BC069287 mRNA. Translation: AAH69287.1 .
    BC111427 mRNA. Translation: AAI11428.1 .
    BC111433 mRNA. Translation: AAI11434.1 .
    BK000201 mRNA. Translation: DAA00358.1 .
    CCDSi CCDS41581.1.
    RefSeqi NP_001091079.1. NM_001097610.2.
    NP_663626.2. NM_145651.2.
    XP_005252861.1. XM_005252804.1.
    XP_005277990.1. XM_005277933.1.
    XP_006725313.1. XM_006725250.1.
    UniGenei Hs.127059.

    3D structure databases

    ProteinModelPortali Q8TD33.
    SMRi Q8TD33. Positions 25-94.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000344545.

    PTM databases

    PhosphoSitei Q8TD33.

    Polymorphism databases

    DMDMi 296452904.

    Proteomic databases

    PRIDEi Q8TD33.

    Protocols and materials databases

    DNASUi 147199.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000342878 ; ENSP00000344545 ; ENSG00000188076 .
    GeneIDi 147199.
    653486.
    KEGGi hsa:147199.
    hsa:653486.
    UCSCi uc001loa.1. human.

    Organism-specific databases

    CTDi 147199.
    GeneCardsi GC11P000187.
    H-InvDB HIX0201712.
    HGNCi HGNC:18394. SCGB1C1.
    MIMi 610176. gene.
    neXtProti NX_Q8TD33.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG27764.
    HOGENOMi HOG000220914.
    HOVERGENi HBG098533.
    InParanoidi Q8TD33.
    OMAi NEFFMDF.
    OrthoDBi EOG74XS9P.
    PhylomeDBi Q8TD33.
    TreeFami TF337061.

    Miscellaneous databases

    NextBioi 85574.
    PROi Q8TD33.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q8TD33.
    CleanExi HS_SCGB1C1.
    Genevestigatori Q8TD33.

    Family and domain databases

    InterProi IPR016126. Secretoglobin.
    IPR028659. Secretoglobin_1C1.
    [Graphical view ]
    PANTHERi PTHR10136:SF7. PTHR10136:SF7. 1 hit.
    Pfami PF01099. Uteroglobin. 1 hit.
    [Graphical view ]
    SMARTi SM00096. UTG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48201. SSF48201. 1 hit.
    PROSITEi PS51311. SCGB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human RYD5, a new secretoglobin."
      Bingle C.D.
      Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ARG-70.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-70.
    4. "Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways."
      Reynolds S.D., Reynolds P.R., Pryhuber G.S., Finder J.D., Stripp B.R.
      Am. J. Respir. Crit. Care Med. 166:1498-1509(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION, VARIANT ARG-70.

    Entry informationi

    Entry nameiSG1C1_HUMAN
    AccessioniPrimary (citable) accession number: Q8TD33
    Secondary accession number(s): A8MSI9, Q14DW0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2006
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 98 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3