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Protein

Secretoglobin family 1C member 1

Gene

SCGB1C1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-33486-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Secretoglobin family 1C member 1
Alternative name(s):
Secretoglobin RYD5
Gene namesi
Name:SCGB1C1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:18394. SCGB1C1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188076.

Polymorphism and mutation databases

BioMutaiSCGB1C1.
DMDMi296452904.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000022333224 – 95Secretoglobin family 1C member 1Add BLAST72

Proteomic databases

PaxDbiQ8TD33.
PRIDEiQ8TD33.

PTM databases

iPTMnetiQ8TD33.
PhosphoSitePlusiQ8TD33.

Expressioni

Gene expression databases

BgeeiENSG00000188076.
CleanExiHS_SCGB1C1.
GenevisibleiQ8TD33. HS.

Organism-specific databases

HPAiCAB012264.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000344545.

Structurei

3D structure databases

ProteinModelPortaliQ8TD33.
SMRiQ8TD33.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the secretoglobin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2P6. Eukaryota.
ENOG4111BH3. LUCA.
GeneTreeiENSGT00390000016583.
HOGENOMiHOG000220914.
HOVERGENiHBG098533.
InParanoidiQ8TD33.
OMAiFFMEFLQ.
OrthoDBiEOG091G17VD.
PhylomeDBiQ8TD33.
TreeFamiTF337061.

Family and domain databases

CDDicd00633. Secretoglobin. 1 hit.
InterProiIPR016126. Secretoglobin.
IPR028659. Secretoglobin_1C1/2.
[Graphical view]
PANTHERiPTHR10136:SF8. PTHR10136:SF8. 1 hit.
PfamiPF01099. Uteroglobin. 1 hit.
[Graphical view]
SUPFAMiSSF48201. SSF48201. 1 hit.
PROSITEiPS51311. SCGB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TD33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL
60 70 80 90
GKYNVNEDAK AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA
Length:95
Mass (Da):10,414
Last modified:May 18, 2010 - v2
Checksum:iF6331EADC96D2392
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_06310270I → R.3 PublicationsCorresponds to variant rs2686894dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY026938 mRNA. Translation: AAK08972.1.
AC069287 Genomic DNA. No translation available.
BC069287 mRNA. Translation: AAH69287.1.
BC111427 mRNA. Translation: AAI11428.1.
BC111433 mRNA. Translation: AAI11434.1.
BK000201 mRNA. Translation: DAA00358.1.
CCDSiCCDS41581.1.
RefSeqiNP_001091079.1. NM_001097610.2.
NP_663626.2. NM_145651.2.
UniGeneiHs.127059.

Genome annotation databases

EnsembliENST00000342878; ENSP00000344545; ENSG00000188076.
GeneIDi147199.
653486.
KEGGihsa:147199.
hsa:653486.
UCSCiuc001loa.1. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY026938 mRNA. Translation: AAK08972.1.
AC069287 Genomic DNA. No translation available.
BC069287 mRNA. Translation: AAH69287.1.
BC111427 mRNA. Translation: AAI11428.1.
BC111433 mRNA. Translation: AAI11434.1.
BK000201 mRNA. Translation: DAA00358.1.
CCDSiCCDS41581.1.
RefSeqiNP_001091079.1. NM_001097610.2.
NP_663626.2. NM_145651.2.
UniGeneiHs.127059.

3D structure databases

ProteinModelPortaliQ8TD33.
SMRiQ8TD33.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000344545.

PTM databases

iPTMnetiQ8TD33.
PhosphoSitePlusiQ8TD33.

Polymorphism and mutation databases

BioMutaiSCGB1C1.
DMDMi296452904.

Proteomic databases

PaxDbiQ8TD33.
PRIDEiQ8TD33.

Protocols and materials databases

DNASUi147199.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000342878; ENSP00000344545; ENSG00000188076.
GeneIDi147199.
653486.
KEGGihsa:147199.
hsa:653486.
UCSCiuc001loa.1. human.

Organism-specific databases

CTDi147199.
653486.
GeneCardsiSCGB1C1.
H-InvDBHIX0201712.
HGNCiHGNC:18394. SCGB1C1.
HPAiCAB012264.
MIMi610176. gene.
neXtProtiNX_Q8TD33.
OpenTargetsiENSG00000188076.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J2P6. Eukaryota.
ENOG4111BH3. LUCA.
GeneTreeiENSGT00390000016583.
HOGENOMiHOG000220914.
HOVERGENiHBG098533.
InParanoidiQ8TD33.
OMAiFFMEFLQ.
OrthoDBiEOG091G17VD.
PhylomeDBiQ8TD33.
TreeFamiTF337061.

Enzyme and pathway databases

BioCyciZFISH:G66-33486-MONOMER.

Miscellaneous databases

PROiQ8TD33.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000188076.
CleanExiHS_SCGB1C1.
GenevisibleiQ8TD33. HS.

Family and domain databases

CDDicd00633. Secretoglobin. 1 hit.
InterProiIPR016126. Secretoglobin.
IPR028659. Secretoglobin_1C1/2.
[Graphical view]
PANTHERiPTHR10136:SF8. PTHR10136:SF8. 1 hit.
PfamiPF01099. Uteroglobin. 1 hit.
[Graphical view]
SUPFAMiSSF48201. SSF48201. 1 hit.
PROSITEiPS51311. SCGB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSG1C1_HUMAN
AccessioniPrimary (citable) accession number: Q8TD33
Secondary accession number(s): A8MSI9, Q14DW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: May 18, 2010
Last modified: November 30, 2016
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.