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Q8TD33

- SG1C1_HUMAN

UniProt

Q8TD33 - SG1C1_HUMAN

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Protein
Secretoglobin family 1C member 1
Gene
SCGB1C1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Secretoglobin family 1C member 1
Alternative name(s):
Secretoglobin RYD5
Gene namesi
Name:SCGB1C1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:18394. SCGB1C1.

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 Reviewed prediction
Add
BLAST
Chaini24 – 9572Secretoglobin family 1C member 1
PRO_0000223332Add
BLAST

Proteomic databases

PRIDEiQ8TD33.

PTM databases

PhosphoSiteiQ8TD33.

Expressioni

Gene expression databases

BgeeiQ8TD33.
CleanExiHS_SCGB1C1.
GenevestigatoriQ8TD33.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000344545.

Structurei

3D structure databases

ProteinModelPortaliQ8TD33.
SMRiQ8TD33. Positions 25-94.

Family & Domainsi

Sequence similaritiesi

Belongs to the secretoglobin family.

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG27764.
HOGENOMiHOG000220914.
HOVERGENiHBG098533.
InParanoidiQ8TD33.
OMAiNEFFMDF.
OrthoDBiEOG74XS9P.
PhylomeDBiQ8TD33.
TreeFamiTF337061.

Family and domain databases

InterProiIPR016126. Secretoglobin.
IPR028659. Secretoglobin_1C1.
[Graphical view]
PANTHERiPTHR10136:SF7. PTHR10136:SF7. 1 hit.
PfamiPF01099. Uteroglobin. 1 hit.
[Graphical view]
SMARTiSM00096. UTG. 1 hit.
[Graphical view]
SUPFAMiSSF48201. SSF48201. 1 hit.
PROSITEiPS51311. SCGB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8TD33-1 [UniParc]FASTAAdd to Basket

« Hide

MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL   50
GKYNVNEDAK AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA 95
Length:95
Mass (Da):10,414
Last modified:May 18, 2010 - v2
Checksum:iF6331EADC96D2392
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti70 – 701I → R.3 Publications
Corresponds to variant rs2686894 [ dbSNP | Ensembl ].
VAR_063102

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY026938 mRNA. Translation: AAK08972.1.
AC069287 Genomic DNA. No translation available.
BC069287 mRNA. Translation: AAH69287.1.
BC111427 mRNA. Translation: AAI11428.1.
BC111433 mRNA. Translation: AAI11434.1.
BK000201 mRNA. Translation: DAA00358.1.
CCDSiCCDS41581.1.
RefSeqiNP_001091079.1. NM_001097610.2.
NP_663626.2. NM_145651.2.
XP_005252861.1. XM_005252804.1.
XP_005277990.1. XM_005277933.1.
XP_006725313.1. XM_006725250.1.
UniGeneiHs.127059.

Genome annotation databases

EnsembliENST00000342878; ENSP00000344545; ENSG00000188076.
GeneIDi147199.
653486.
KEGGihsa:147199.
hsa:653486.
UCSCiuc001loa.1. human.

Polymorphism databases

DMDMi296452904.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY026938 mRNA. Translation: AAK08972.1 .
AC069287 Genomic DNA. No translation available.
BC069287 mRNA. Translation: AAH69287.1 .
BC111427 mRNA. Translation: AAI11428.1 .
BC111433 mRNA. Translation: AAI11434.1 .
BK000201 mRNA. Translation: DAA00358.1 .
CCDSi CCDS41581.1.
RefSeqi NP_001091079.1. NM_001097610.2.
NP_663626.2. NM_145651.2.
XP_005252861.1. XM_005252804.1.
XP_005277990.1. XM_005277933.1.
XP_006725313.1. XM_006725250.1.
UniGenei Hs.127059.

3D structure databases

ProteinModelPortali Q8TD33.
SMRi Q8TD33. Positions 25-94.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000344545.

PTM databases

PhosphoSitei Q8TD33.

Polymorphism databases

DMDMi 296452904.

Proteomic databases

PRIDEi Q8TD33.

Protocols and materials databases

DNASUi 147199.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000342878 ; ENSP00000344545 ; ENSG00000188076 .
GeneIDi 147199.
653486.
KEGGi hsa:147199.
hsa:653486.
UCSCi uc001loa.1. human.

Organism-specific databases

CTDi 147199.
GeneCardsi GC11P000187.
H-InvDB HIX0201712.
HGNCi HGNC:18394. SCGB1C1.
MIMi 610176. gene.
neXtProti NX_Q8TD33.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG27764.
HOGENOMi HOG000220914.
HOVERGENi HBG098533.
InParanoidi Q8TD33.
OMAi NEFFMDF.
OrthoDBi EOG74XS9P.
PhylomeDBi Q8TD33.
TreeFami TF337061.

Miscellaneous databases

NextBioi 85574.
PROi Q8TD33.
SOURCEi Search...

Gene expression databases

Bgeei Q8TD33.
CleanExi HS_SCGB1C1.
Genevestigatori Q8TD33.

Family and domain databases

InterProi IPR016126. Secretoglobin.
IPR028659. Secretoglobin_1C1.
[Graphical view ]
PANTHERi PTHR10136:SF7. PTHR10136:SF7. 1 hit.
Pfami PF01099. Uteroglobin. 1 hit.
[Graphical view ]
SMARTi SM00096. UTG. 1 hit.
[Graphical view ]
SUPFAMi SSF48201. SSF48201. 1 hit.
PROSITEi PS51311. SCGB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Human RYD5, a new secretoglobin."
    Bingle C.D.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ARG-70.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-70.
  4. "Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways."
    Reynolds S.D., Reynolds P.R., Pryhuber G.S., Finder J.D., Stripp B.R.
    Am. J. Respir. Crit. Care Med. 166:1498-1509(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, VARIANT ARG-70.

Entry informationi

Entry nameiSG1C1_HUMAN
AccessioniPrimary (citable) accession number: Q8TD33
Secondary accession number(s): A8MSI9, Q14DW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: May 18, 2010
Last modified: July 9, 2014
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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