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Q8TD33 (SG1C1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Secretoglobin family 1C member 1
Alternative name(s):
Secretoglobin RYD5
Gene names
Name:SCGB1C1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length95 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the secretoglobin family.

Ontologies

Keywords
   Cellular componentSecreted
   Coding sequence diversityPolymorphism
   DomainSignal
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 9572Secretoglobin family 1C member 1
PRO_0000223332

Natural variations

Natural variant701I → R. Ref.1 Ref.3 Ref.4
Corresponds to variant rs2686894 [ dbSNP | Ensembl ].
VAR_063102

Sequences

Sequence LengthMass (Da)Tools
Q8TD33 [UniParc].

Last modified May 18, 2010. Version 2.
Checksum: F6331EADC96D2392

FASTA9510,414
        10         20         30         40         50         60 
MKGSRALLLV ALTLFCICRM ATGEDNDEFF MDFLQTLLVG TPEELYEGTL GKYNVNEDAK 

        70         80         90 
AAMTELKSCI DGLQPMHKAE LVKLLVQVLG SQDGA 

« Hide

References

« Hide 'large scale' references
[1]"Human RYD5, a new secretoglobin."
Bingle C.D.
Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ARG-70.
[2]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ARG-70.
[4]"Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways."
Reynolds S.D., Reynolds P.R., Pryhuber G.S., Finder J.D., Stripp B.R.
Am. J. Respir. Crit. Care Med. 166:1498-1509(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION, VARIANT ARG-70.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY026938 mRNA. Translation: AAK08972.1.
AC069287 Genomic DNA. No translation available.
BC069287 mRNA. Translation: AAH69287.1.
BC111427 mRNA. Translation: AAI11428.1.
BC111433 mRNA. Translation: AAI11434.1.
BK000201 mRNA. Translation: DAA00358.1.
RefSeqNP_001091079.1. NM_001097610.2.
NP_663626.2. NM_145651.2.
XP_005252861.1. XM_005252804.1.
XP_005277990.1. XM_005277933.1.
UniGeneHs.127059.

3D structure databases

ProteinModelPortalQ8TD33.
SMRQ8TD33. Positions 25-94.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000344545.

PTM databases

PhosphoSiteQ8TD33.

Polymorphism databases

DMDM296452904.

Proteomic databases

PRIDEQ8TD33.

Protocols and materials databases

DNASU147199.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000342878; ENSP00000344545; ENSG00000188076.
GeneID147199.
653486.
KEGGhsa:147199.
hsa:653486.
UCSCuc001loa.1. human.

Organism-specific databases

CTD147199.
GeneCardsGC11P000187.
H-InvDBHIX0201712.
HGNCHGNC:18394. SCGB1C1.
MIM610176. gene.
neXtProtNX_Q8TD33.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG27764.
HOGENOMHOG000220914.
HOVERGENHBG098533.
InParanoidQ8TD33.
OMACIDGLQP.
OrthoDBEOG74XS9P.
PhylomeDBQ8TD33.
TreeFamTF337061.

Gene expression databases

BgeeQ8TD33.
CleanExHS_SCGB1C1.
GenevestigatorQ8TD33.

Family and domain databases

InterProIPR016126. Secretoglobin.
IPR028659. Secretoglobin_1C1.
[Graphical view]
PANTHERPTHR10136:SF1. PTHR10136:SF1. 1 hit.
PfamPF01099. Uteroglobin. 1 hit.
[Graphical view]
SMARTSM00096. UTG. 1 hit.
[Graphical view]
SUPFAMSSF48201. SSF48201. 1 hit.
PROSITEPS51311. SCGB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio85574.
PROQ8TD33.
SOURCESearch...

Entry information

Entry nameSG1C1_HUMAN
AccessionPrimary (citable) accession number: Q8TD33
Secondary accession number(s): A8MSI9, Q14DW0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: May 18, 2010
Last modified: April 16, 2014
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM