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Q8TCZ2

- C99L2_HUMAN

UniProt

Q8TCZ2 - C99L2_HUMAN

Protein

CD99 antigen-like protein 2

Gene

CD99L2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 By similarity. Homophilic adhesion molecule, but these interactions may not be required for cell aggregation By similarity.By similarity

    GO - Biological processi

    1. cell adhesion Source: UniProtKB-KW

    Keywords - Biological processi

    Cell adhesion

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    CD99 antigen-like protein 2
    Alternative name(s):
    MIC2-like protein 1
    CD_antigen: CD99
    Gene namesi
    Name:CD99L2
    Synonyms:MIC2L1
    ORF Names:UNQ1964/PRO4486
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:18237. CD99L2.

    Subcellular locationi

    Cell membrane By similarity; Single-pass type I membrane protein By similarity; Extracellular side By similarity. Cell junction By similarity

    GO - Cellular componenti

    1. cell junction Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell junction, Cell membrane, Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA30805.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2525Sequence AnalysisAdd
    BLAST
    Chaini26 – 262237CD99 antigen-like protein 2PRO_0000340092Add
    BLAST

    Post-translational modificationi

    O-glycosylated.By similarity

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    MaxQBiQ8TCZ2.
    PaxDbiQ8TCZ2.
    PRIDEiQ8TCZ2.

    PTM databases

    PhosphoSiteiQ8TCZ2.

    Expressioni

    Tissue specificityi

    Expressed in many tissues, with low expression in thymus.1 Publication

    Gene expression databases

    ArrayExpressiQ8TCZ2.
    BgeeiQ8TCZ2.
    CleanExiHS_CD99L2.
    GenevestigatoriQ8TCZ2.

    Organism-specific databases

    HPAiHPA038782.
    HPA038783.

    Interactioni

    Protein-protein interaction databases

    BioGridi123726. 2 interactions.
    IntActiQ8TCZ2. 1 interaction.
    MINTiMINT-4724363.
    STRINGi9606.ENSP00000359403.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TCZ2.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini26 – 185160ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini207 – 26256CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei186 – 20621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi49 – 546Poly-Thr
    Compositional biasi99 – 1024Poly-Thr
    Compositional biasi141 – 1444Poly-Gly
    Compositional biasi253 – 2597Poly-Pro

    Sequence similaritiesi

    Belongs to the CD99 family.Curated

    Keywords - Domaini

    Signal, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG42091.
    HOVERGENiHBG067989.
    InParanoidiQ8TCZ2.
    OMAiKYSTLHT.
    PhylomeDBiQ8TCZ2.
    TreeFamiTF332323.

    Family and domain databases

    InterProiIPR022078. CD99L2.
    [Graphical view]
    PfamiPF12301. CD99L2. 1 hit.
    [Graphical view]

    Sequences (6)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 6 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q8TCZ2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MVAWRSAFLV CLAFSLATLV QRGSGDFDDF NLEDAVKETS SVKQPWDHTT    50
    TTTTNRPGTT RAPAKPPGSG LDLADALDDQ DDGRRKPGIG GRERWNHVTT 100
    TTKRPVTTRA PANTLGNDFD LADALDDRND RDDGRRKPIA GGGGFSDKDL 150
    EDIVGGGEYK PDKGKGDGRY GSNDDPGSGM VAEPGTIAGV ASALAMALIG 200
    AVSSYISYQQ KKFCFSIQQG LNADYVKGEN LEAVVCEEPQ VKYSTLHTQS 250
    AEPPPPPEPA RI 262
    Length:262
    Mass (Da):27,986
    Last modified:June 1, 2002 - v1
    Checksum:i3A254961DD32C191
    GO
    Isoform 2 (identifier: Q8TCZ2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         45-93: Missing.

    Show »
    Length:213
    Mass (Da):22,833
    Checksum:iF90595DAA99BA7D5
    GO
    Isoform 3 (identifier: Q8TCZ2-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         44-44: Q → R
         45-116: Missing.

    Show »
    Length:190
    Mass (Da):20,300
    Checksum:iF21A43C7F6B319F6
    GO
    Isoform 4 (identifier: Q8TCZ2-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         44-145: QPWDHTTTTT...RKPIAGGGGF → PALGMYHKLD...GFKAHLDNPG
         146-262: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:145
    Mass (Da):15,708
    Checksum:i777A148801613231
    GO
    Isoform 5 (identifier: Q8TCZ2-5) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         68-68: G → GPTEG
         218-219: QQ → QHAAAGQE

    Note: No experimental confirmation available.

    Show »
    Length:272
    Mass (Da):28,907
    Checksum:i6A92D41FDA0C5FD4
    GO
    Isoform 6 (identifier: Q8TCZ2-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         93-165: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:189
    Mass (Da):20,032
    Checksum:i9F21AFB2BA02904B
    GO

    Sequence cautioni

    The sequence CAB66515.1 differs from that shown. Reason: Frameshift at position 156.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti109 – 1091R → I in BAF82889. (PubMed:14702039)Curated
    Sequence conflicti128 – 1281R → Q in BAG54124. (PubMed:14702039)Curated
    Sequence conflicti170 – 1701Y → H in BAF82889. (PubMed:14702039)Curated
    Sequence conflicti176 – 1761P → R in BAF84064. (PubMed:14702039)Curated
    Sequence conflicti229 – 2291E → G in BAG56778. (PubMed:14702039)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei44 – 145102QPWDH…GGGGF → PALGMYHKLDGLKQQNFILS LFWMLEVLYQGVGWATFSLK ALGKNLSLTFPTSGGSRCSL VCGCITPISASVVTWCSPFC VSLLSLTKMLVSGFKAHLDN PG in isoform 4. 1 PublicationVSP_034181Add
    BLAST
    Alternative sequencei44 – 441Q → R in isoform 3. 1 PublicationVSP_034182
    Alternative sequencei45 – 11672Missing in isoform 3. 1 PublicationVSP_034183Add
    BLAST
    Alternative sequencei45 – 9349Missing in isoform 2. 2 PublicationsVSP_034184Add
    BLAST
    Alternative sequencei68 – 681G → GPTEG in isoform 5. 1 PublicationVSP_041815
    Alternative sequencei93 – 16573Missing in isoform 6. 1 PublicationVSP_044663Add
    BLAST
    Alternative sequencei146 – 262117Missing in isoform 4. 1 PublicationVSP_034185Add
    BLAST
    Alternative sequencei218 – 2192QQ → QHAAAGQE in isoform 5. 1 PublicationVSP_041816

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY078165 mRNA. Translation: AAL86617.1.
    AY078166 mRNA. Translation: AAL86618.1.
    AY078167 mRNA. Translation: AAL86619.1.
    AL136580 mRNA. Translation: CAB66515.1. Frameshift.
    AY358837 mRNA. Translation: AAQ89196.1.
    AK290200 mRNA. Translation: BAF82889.1.
    AK291375 mRNA. Translation: BAF84064.1.
    AK293244 mRNA. Translation: BAG56778.1.
    AK125020 mRNA. Translation: BAG54124.1.
    AF002223 Genomic DNA. No translation available.
    AF274573 Genomic DNA. No translation available.
    CH471169 Genomic DNA. Translation: EAW99391.1.
    CH471169 Genomic DNA. Translation: EAW99392.1.
    CH471169 Genomic DNA. Translation: EAW99393.1.
    CH471169 Genomic DNA. Translation: EAW99395.1.
    BC025729 mRNA. Translation: AAH25729.1.
    BC030536 mRNA. Translation: AAH30536.1.
    CCDSiCCDS14697.1. [Q8TCZ2-3]
    CCDS14698.1. [Q8TCZ2-2]
    CCDS35427.1. [Q8TCZ2-1]
    CCDS55527.1. [Q8TCZ2-6]
    RefSeqiNP_001171737.1. NM_001184808.1. [Q8TCZ2-6]
    NP_001229543.1. NM_001242614.1. [Q8TCZ2-5]
    NP_113650.2. NM_031462.3. [Q8TCZ2-1]
    NP_604394.1. NM_134445.3. [Q8TCZ2-3]
    NP_604395.1. NM_134446.3. [Q8TCZ2-2]
    UniGeneiHs.522805.

    Genome annotation databases

    EnsembliENST00000355149; ENSP00000347275; ENSG00000102181. [Q8TCZ2-3]
    ENST00000370377; ENSP00000359403; ENSG00000102181. [Q8TCZ2-1]
    ENST00000437787; ENSP00000394858; ENSG00000102181. [Q8TCZ2-6]
    ENST00000466436; ENSP00000417697; ENSG00000102181. [Q8TCZ2-2]
    GeneIDi83692.
    KEGGihsa:83692.
    UCSCiuc004fek.3. human. [Q8TCZ2-5]
    uc004fel.3. human. [Q8TCZ2-1]
    uc004fem.3. human. [Q8TCZ2-2]
    uc004fen.3. human. [Q8TCZ2-3]

    Polymorphism databases

    DMDMi74730601.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY078165 mRNA. Translation: AAL86617.1 .
    AY078166 mRNA. Translation: AAL86618.1 .
    AY078167 mRNA. Translation: AAL86619.1 .
    AL136580 mRNA. Translation: CAB66515.1 . Frameshift.
    AY358837 mRNA. Translation: AAQ89196.1 .
    AK290200 mRNA. Translation: BAF82889.1 .
    AK291375 mRNA. Translation: BAF84064.1 .
    AK293244 mRNA. Translation: BAG56778.1 .
    AK125020 mRNA. Translation: BAG54124.1 .
    AF002223 Genomic DNA. No translation available.
    AF274573 Genomic DNA. No translation available.
    CH471169 Genomic DNA. Translation: EAW99391.1 .
    CH471169 Genomic DNA. Translation: EAW99392.1 .
    CH471169 Genomic DNA. Translation: EAW99393.1 .
    CH471169 Genomic DNA. Translation: EAW99395.1 .
    BC025729 mRNA. Translation: AAH25729.1 .
    BC030536 mRNA. Translation: AAH30536.1 .
    CCDSi CCDS14697.1. [Q8TCZ2-3 ]
    CCDS14698.1. [Q8TCZ2-2 ]
    CCDS35427.1. [Q8TCZ2-1 ]
    CCDS55527.1. [Q8TCZ2-6 ]
    RefSeqi NP_001171737.1. NM_001184808.1. [Q8TCZ2-6 ]
    NP_001229543.1. NM_001242614.1. [Q8TCZ2-5 ]
    NP_113650.2. NM_031462.3. [Q8TCZ2-1 ]
    NP_604394.1. NM_134445.3. [Q8TCZ2-3 ]
    NP_604395.1. NM_134446.3. [Q8TCZ2-2 ]
    UniGenei Hs.522805.

    3D structure databases

    ProteinModelPortali Q8TCZ2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 123726. 2 interactions.
    IntActi Q8TCZ2. 1 interaction.
    MINTi MINT-4724363.
    STRINGi 9606.ENSP00000359403.

    PTM databases

    PhosphoSitei Q8TCZ2.

    Polymorphism databases

    DMDMi 74730601.

    Proteomic databases

    MaxQBi Q8TCZ2.
    PaxDbi Q8TCZ2.
    PRIDEi Q8TCZ2.

    Protocols and materials databases

    DNASUi 83692.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000355149 ; ENSP00000347275 ; ENSG00000102181 . [Q8TCZ2-3 ]
    ENST00000370377 ; ENSP00000359403 ; ENSG00000102181 . [Q8TCZ2-1 ]
    ENST00000437787 ; ENSP00000394858 ; ENSG00000102181 . [Q8TCZ2-6 ]
    ENST00000466436 ; ENSP00000417697 ; ENSG00000102181 . [Q8TCZ2-2 ]
    GeneIDi 83692.
    KEGGi hsa:83692.
    UCSCi uc004fek.3. human. [Q8TCZ2-5 ]
    uc004fel.3. human. [Q8TCZ2-1 ]
    uc004fem.3. human. [Q8TCZ2-2 ]
    uc004fen.3. human. [Q8TCZ2-3 ]

    Organism-specific databases

    CTDi 83692.
    GeneCardsi GC0XM149934.
    HGNCi HGNC:18237. CD99L2.
    HPAi HPA038782.
    HPA038783.
    MIMi 300846. gene.
    neXtProti NX_Q8TCZ2.
    PharmGKBi PA30805.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG42091.
    HOVERGENi HBG067989.
    InParanoidi Q8TCZ2.
    OMAi KYSTLHT.
    PhylomeDBi Q8TCZ2.
    TreeFami TF332323.

    Miscellaneous databases

    ChiTaRSi CD99L2. human.
    GeneWikii CD99L2.
    GenomeRNAii 83692.
    NextBioi 72651.
    PROi Q8TCZ2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q8TCZ2.
    Bgeei Q8TCZ2.
    CleanExi HS_CD99L2.
    Genevestigatori Q8TCZ2.

    Family and domain databases

    InterProi IPR022078. CD99L2.
    [Graphical view ]
    Pfami PF12301. CD99L2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, genomic organization, alternative transcripts and expression analysis of CD99L2, a novel paralog of human CD99, and identification of evolutionary conserved motifs."
      Suh Y.H., Shin Y.K., Kook M.-C., Oh K.I., Park W.S., Kim S.H., Lee I.-S., Park H.J., Huh T.-L., Park S.H.
      Gene 307:63-76(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), ALTERNATIVE SPLICING, TISSUE SPECIFICITY.
      Tissue: Skeletal muscle and Thymocyte.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Amygdala.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 5 AND 6).
      Tissue: Brain and Thalamus.
    5. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 4).
      Tissue: Brain and Lung.
    8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.

    Entry informationi

    Entry nameiC99L2_HUMAN
    AccessioniPrimary (citable) accession number: Q8TCZ2
    Secondary accession number(s): A8K2D5
    , A8K5R0, B3KWG2, B4DDL7, E7EMK5, E9PD27, Q8TAW2, Q8TCZ0, Q8TCZ1, Q9BQG9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 10, 2008
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3