##gff-version 3
Q8TCT9	UniProtKB	Chain	1	377	.	.	.	ID=PRO_0000073907;Note=Minor histocompatibility antigen H13	
Q8TCT9	UniProtKB	Topological domain	1	31	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12077416,ECO:0000269|PubMed:15385547;Dbxref=PMID:12077416,PMID:15385547	
Q8TCT9	UniProtKB	Transmembrane	32	52	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	53	77	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	78	98	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	99	100	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	101	121	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	122	157	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	158	178	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	179	181	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	182	202	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	203	209	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	210	230	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	231	256	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT9	UniProtKB	Transmembrane	257	277	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	278	290	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	291	311	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	312	314	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Transmembrane	315	335	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT9	UniProtKB	Topological domain	336	377	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT9	UniProtKB	Region	1	27	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8TCT9	UniProtKB	Region	345	377	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8TCT9	UniProtKB	Motif	317	319	.	.	.	Note=PAL	
Q8TCT9	UniProtKB	Compositional bias	13	27	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q8TCT9	UniProtKB	Active site	219	219	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P49810	
Q8TCT9	UniProtKB	Active site	265	265	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P49810	
Q8TCT9	UniProtKB	Modified residue	367	367	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:24275569;Dbxref=PMID:24275569	
Q8TCT9	UniProtKB	Glycosylation	10	10	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218	
Q8TCT9	UniProtKB	Glycosylation	20	20	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19159218;Dbxref=PMID:19159218	
Q8TCT9	UniProtKB	Alternative sequence	181	222	.	.	.	ID=VSP_015082;Note=In isoform 5. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT9	UniProtKB	Alternative sequence	347	347	.	.	.	ID=VSP_005196;Note=In isoform 2. E->ESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYE;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:12139484;Dbxref=PMID:12139484	
Q8TCT9	UniProtKB	Alternative sequence	348	377	.	.	.	ID=VSP_015083;Note=In isoform 4. ESNPKDPAAVTESKEGTEASASKGLEKKEK->SSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAM;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:12139484,ECO:0000303|PubMed:16730383;Dbxref=PMID:12139484,PMID:16730383	
Q8TCT9	UniProtKB	Natural variant	259	259	.	.	.	ID=VAR_014274;Note=A->P;Dbxref=dbSNP:rs1044419	
Q8TCT9	UniProtKB	Mutagenesis	10	10	.	.	.	Note=Abolishes N-glycosylation%3B when associated with Q-20. N->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12077416;Dbxref=PMID:12077416	
Q8TCT9	UniProtKB	Mutagenesis	20	20	.	.	.	Note=Abolishes N-glycosylation%3B when associated with Q-10. N->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12077416;Dbxref=PMID:12077416	
Q8TCT9	UniProtKB	Mutagenesis	219	219	.	.	.	Note=Abolishes proteolysis of PSEN1. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14741365;Dbxref=PMID:14741365	
Q8TCT9	UniProtKB	Mutagenesis	264	264	.	.	.	Note=No effect on proteolysis of PSEN1. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14741365;Dbxref=PMID:14741365	
Q8TCT9	UniProtKB	Mutagenesis	265	265	.	.	.	Note=No effect on inhibitor binding%3B abolishes catalytic activity. Abolishes proteolysis of PSEN1. Abolishes proteolysis of XBP1 isoform 1 and increases interaction with XBP1 isoform 1. D->A;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12077416,ECO:0000269|PubMed:14741365,ECO:0000269|PubMed:25239945;Dbxref=PMID:12077416,PMID:14741365,PMID:25239945	
Q8TCT9	UniProtKB	Mutagenesis	317	317	.	.	.	Note=Abolishes proteolysis of PSEN1. P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:14741365;Dbxref=PMID:14741365	
Q8TCT9	UniProtKB	Sequence conflict	132	132	.	.	.	Note=S->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT9	UniProtKB	Sequence conflict	150	150	.	.	.	Note=K->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT9	UniProtKB	Sequence conflict	159	159	.	.	.	Note=D->A;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT9	UniProtKB	Sequence conflict	235	235	.	.	.	Note=S->F;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT9	UniProtKB	Sequence conflict	295	295	.	.	.	Note=F->Y;Ontology_term=ECO:0000305;evidence=ECO:0000305