##gff-version 3
Q8TCT6	UniProtKB	Chain	1	384	.	.	.	ID=PRO_0000073912;Note=Signal peptide peptidase-like 3	
Q8TCT6	UniProtKB	Topological domain	1	8	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT6	UniProtKB	Transmembrane	9	29	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	30	74	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT6	UniProtKB	Transmembrane	75	95	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	96	97	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	98	118	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	119	136	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	137	159	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	160	164	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	165	185	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	186	190	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	191	211	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	212	262	.	.	.	Note=Lumenal;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT6	UniProtKB	Transmembrane	263	283	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	284	311	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	312	332	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	333	339	.	.	.	Note=Lumenal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Transmembrane	340	360	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q8TCT6	UniProtKB	Topological domain	361	384	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15385547;Dbxref=PMID:15385547	
Q8TCT6	UniProtKB	Motif	341	343	.	.	.	Note=PAL	
Q8TCT6	UniProtKB	Active site	200	200	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P49810	
Q8TCT6	UniProtKB	Active site	271	271	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P49810	
Q8TCT6	UniProtKB	Alternative sequence	1	215	.	.	.	ID=VSP_005205;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q8TCT6	UniProtKB	Mutagenesis	200	200	.	.	.	Note=Does not affect complex glycosylation pattern of cellular glycoproteins%3B when associated with A-271. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25354954;Dbxref=PMID:25354954	
Q8TCT6	UniProtKB	Mutagenesis	271	271	.	.	.	Note=Loss of intramembrane-cleaving activity toward the simian foamy virus envelope glycoprotein gp130. Does not affect complex glycosylation pattern of cellular glycoproteins%3B when associated with A-200. D->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:23132852,ECO:0000269|PubMed:25354954;Dbxref=PMID:23132852,PMID:25354954	
Q8TCT6	UniProtKB	Sequence conflict	59	81	.	.	.	Note=NSTNNSIQTIDSTQALFLPIGAS->EQEPIIGFQPMDSTRARFLPMGAC;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q8TCT6	UniProtKB	Sequence conflict	139	139	.	.	.	Note=F->Y;Ontology_term=ECO:0000305;evidence=ECO:0000305