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Protein

V-type proton ATPase subunit a

Gene

TCIRG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
Name:TCIRG1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000110719.9
HGNCiHGNC:11647 TCIRG1

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000110719

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8TCH1

Expressioni

Gene expression databases

BgeeiENSG00000110719

Family & Domainsi

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2189 Eukaryota
COG1269 LUCA
GeneTreeiENSGT00390000004941

Family and domain databases

InterProiView protein in InterPro
IPR002490 V-ATPase_116kDa_su
PANTHERiPTHR11629 PTHR11629, 1 hit
PfamiView protein in Pfam
PF01496 V_ATPase_I, 1 hit

Sequencei

Sequence statusi: Fragment.

Q8TCH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DDEEEAELVP SEVLMHQAIH TIEFCLGCVS NTASYLRLWA LSLAHARWNS
60
RTSSTQARAT S
Length:61
Mass (Da):6,805
Last modified:June 1, 2002 - v1
Checksum:iB5F91060BEFB3D01
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002807 Genomic DNA No translation available.
AF497545 mRNA Translation: AAM18704.1
UniGeneiHs.495985
Hs.716672

Genome annotation databases

EnsembliENST00000530063; ENSP00000432957; ENSG00000110719
UCSCiuc058elu.1 human

Similar proteinsi

Entry informationi

Entry nameiQ8TCH1_HUMAN
AccessioniPrimary (citable) accession number: Q8TCH1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: April 25, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported