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Q8TCE1

- Q8TCE1_HUMAN

UniProt

Q8TCE1 - Q8TCE1_HUMAN

Protein
Submitted name:

SERPINC1 protein

Gene

SERPINC1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. heparin binding Source: InterPro
    2. serine-type endopeptidase inhibitor activity Source: InterPro

    GO - Biological processi

    1. regulation of blood coagulation, intrinsic pathway Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    SERPINC1 proteinImported
    Gene namesi
    Name:SERPINC1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: InterPro

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8TCE1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8TCE1.
    SMRiQ8TCE1. Positions 37-258.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the serpin family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000150480.
    HOVERGENiHBG073386.

    Family and domain databases

    InterProiIPR015555. AT-III.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view]
    PANTHERiPTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF53. PTHR11461:SF53. 1 hit.
    PfamiPF00079. Serpin. 2 hits.
    [Graphical view]
    SMARTiSM00093. SERPIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF56574. SSF56574. 2 hits.
    PROSITEiPS00284. SERPIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8TCE1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYSNVIGTVT SGKRKVYLLS LLLIGFWDCV TCHGSPVDIC TAKPRDIPMN    50
    PMCIYRSPEK KATEDEGSEQ KIPEATNRRV WELSKANSRF ATTFYQHLAD 100
    SKNDNDNIFL SPLSISTAFA MTKLGACNDT LQQLMEVFKF DTISEKTSDQ 150
    IHFFFAKLNC RLYRKANKSS KLVSANRLFG DKSLTFNDLY VSDAFHKAFL 200
    EVNEEGSEAA ASTAVVIAGR SLNPNRVTFK ANRPFLVFIR EVPLNTIIFM 250
    GRVANPCVK 259
    Length:259
    Mass (Da):29,092
    Last modified:June 1, 2002 - v1
    Checksum:i8386705A82B8EC8D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC022309 mRNA. Translation: AAH22309.1.
    UniGeneiHs.75599.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC022309 mRNA. Translation: AAH22309.1 .
    UniGenei Hs.75599.

    3D structure databases

    ProteinModelPortali Q8TCE1.
    SMRi Q8TCE1. Positions 37-258.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q8TCE1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOGENOMi HOG000150480.
    HOVERGENi HBG073386.

    Miscellaneous databases

    ChiTaRSi SERPINC1. human.

    Family and domain databases

    InterProi IPR015555. AT-III.
    IPR023795. Serpin_CS.
    IPR023796. Serpin_dom.
    IPR000215. Serpin_fam.
    [Graphical view ]
    PANTHERi PTHR11461. PTHR11461. 1 hit.
    PTHR11461:SF53. PTHR11461:SF53. 1 hit.
    Pfami PF00079. Serpin. 2 hits.
    [Graphical view ]
    SMARTi SM00093. SERPIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56574. SSF56574. 2 hits.
    PROSITEi PS00284. SERPIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LiverImported.

    Entry informationi

    Entry nameiQ8TCE1_HUMAN
    AccessioniPrimary (citable) accession number: Q8TCE1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.