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Protein

UPF0729 protein C18orf32

Gene

C18orf32

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May activate the NF-kappa-B signaling pathway.1 Publication

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0729 protein C18orf32
Alternative name(s):
Putative NF-kappa-B-activating protein 200
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000177576.11
HGNCiHGNC:31690 C18orf32
neXtProtiNX_Q8TCD1

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162378602

Polymorphism and mutation databases

BioMutaiC18orf32

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003219081 – 76UPF0729 protein C18orf32Add BLAST76

Proteomic databases

EPDiQ8TCD1
MaxQBiQ8TCD1
PaxDbiQ8TCD1
PeptideAtlasiQ8TCD1
PRIDEiQ8TCD1

PTM databases

iPTMnetiQ8TCD1
PhosphoSitePlusiQ8TCD1

Expressioni

Gene expression databases

BgeeiENSG00000177576
CleanExiHS_C18orf32
GenevisibleiQ8TCD1 HS

Organism-specific databases

HPAiHPA040921

Interactioni

Protein-protein interaction databases

BioGridi139005, 2 interactors
IntActiQ8TCD1, 5 interactors
STRINGi9606.ENSP00000323199

Structurei

3D structure databases

ProteinModelPortaliQ8TCD1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0729 family.Curated

Phylogenomic databases

eggNOGiENOG410J3GD Eukaryota
ENOG410Y1I3 LUCA
GeneTreeiENSGT00390000018741
HOGENOMiHOG000111951
HOVERGENiHBG107759
InParanoidiQ8TCD1
OMAiSRMWPRK
PhylomeDBiQ8TCD1
TreeFamiTF324662

Family and domain databases

InterProiView protein in InterPro
IPR026776 UPF0729
PANTHERiPTHR13456 PTHR13456, 1 hit
PfamiView protein in Pfam
PF14975 DUF4512, 1 hit

Sequencei

Sequence statusi: Complete.

Q8TCD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCIPCIVIP VLLWIYKKFL EPYIYPLVSP FVSRIWPKKA IQESNDTNKG
60 70
KVNFKGADMN GLPTKGPTEI CDKKKD
Length:76
Mass (Da):8,669
Last modified:June 1, 2002 - v1
Checksum:i649F9A02249FAD5E
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03937437P → H. Corresponds to variant dbSNP:rs11537626Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB097012 mRNA Translation: BAC77365.1
AK291882 mRNA Translation: BAF84571.1
BC022357 mRNA Translation: AAH22357.1
BC093004 mRNA Translation: AAH93004.1
CCDSiCCDS32831.1
RefSeqiNP_001030177.1, NM_001035005.3
NP_001186275.1, NM_001199346.1
UniGeneiHs.603040

Genome annotation databases

EnsembliENST00000318240; ENSP00000323199; ENSG00000177576
ENST00000582392; ENSP00000462538; ENSG00000177576
ENST00000613385; ENSP00000480941; ENSG00000177576
GeneIDi497661
KEGGihsa:497661
UCSCiuc002ldk.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCR032_HUMAN
AccessioniPrimary (citable) accession number: Q8TCD1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2002
Last modified: February 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health