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Protein

Coiled-coil domain-containing glutamate-rich protein 1

Gene

CCER1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing glutamate-rich protein 1
Gene namesi
Name:CCER1
Synonyms:C12orf12
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000197651.4.
HGNCiHGNC:28373. CCER1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197651.
PharmGKBiPA142672294.

Polymorphism and mutation databases

BioMutaiCCER1.
DMDMi74730573.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002888571 – 406Coiled-coil domain-containing glutamate-rich protein 1Add BLAST406

Proteomic databases

PaxDbiQ8TC90.
PeptideAtlasiQ8TC90.
PRIDEiQ8TC90.

PTM databases

iPTMnetiQ8TC90.
PhosphoSitePlusiQ8TC90.

Expressioni

Gene expression databases

BgeeiENSG00000197651.
CleanExiHS_C12orf12.
ExpressionAtlasiQ8TC90. baseline and differential.
GenevisibleiQ8TC90. HS.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi128212. 7 interactors.
IntActiQ8TC90. 11 interactors.
MINTiMINT-1450617.
STRINGi9606.ENSP00000351727.

Structurei

3D structure databases

ProteinModelPortaliQ8TC90.
SMRiQ8TC90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili199 – 225Sequence analysisAdd BLAST27
Coiled coili274 – 359Sequence analysisAdd BLAST86

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi15 – 25Poly-GlyAdd BLAST11
Compositional biasi266 – 376Glu-richAdd BLAST111

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410J28X. Eukaryota.
ENOG4111YIJ. LUCA.
GeneTreeiENSGT00730000111529.
HOGENOMiHOG000111754.
HOVERGENiHBG096611.
InParanoidiQ8TC90.
OMAiKKRWGRR.
OrthoDBiEOG091G0F97.
PhylomeDBiQ8TC90.

Family and domain databases

InterProiView protein in InterPro
IPR027889. CCER1.
PfamiView protein in Pfam
PF15482. CCER1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8TC90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQTLDTRED PLNLGGGGGG GCGCGWAHSA SLSSWSSCHR RRPGAPAYNR
60 70 80 90 100
PHRYSPKTEY GPPRKQPKQQ HGPGFWFQPP VCSNWGCWGG PWRPPPPGFW
110 120 130 140 150
KFPCPVQVFR VYGLHPLCFC CCSCWSGSWN PGWVKPPGRK KRWGRRGRGL
160 170 180 190 200
RHHPRHSYPR SPPADVSTLP RPVKLYEWRE PGMRAPPNTT QFIMNQIYED
210 220 230 240 250
MRQQEKVERQ QEALRAQKAT VSGEASPARS SGNDAPPGGS KETWGLQETL
260 270 280 290 300
YGFVQNPSLA FSPNPEENQS LAPLLVEEEE EKKNDDEEEY DQEVCDAKEA
310 320 330 340 350
SEEEEEVEDE EEEVEDEEEE EVEEAEYVEE GEEELEEEEL EEEEEVLEEN
360 370 380 390 400
EQRGEEFHLP LEMPLSIFVE AEEKRENFIS CTFLNPEQII PKVPQESLFM

AQDFNC
Length:406
Mass (Da):46,482
Last modified:June 1, 2002 - v1
Checksum:iFBB9072D7F976FE6
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_059617286D → E. Corresponds to variant dbSNP:rs11105882Ensembl.1
Natural variantiVAR_032512379I → M1 PublicationCorresponds to variant dbSNP:rs17855513Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC024183 mRNA. Translation: AAH24183.1.
BC026075 mRNA. Translation: AAH26075.1.
BC027600 mRNA. Translation: AAH27600.1.
BC034491 mRNA. Translation: AAH34491.1.
CCDSiCCDS9036.1.
RefSeqiNP_689851.1. NM_152638.3.
UniGeneiHs.128574.

Genome annotation databases

EnsembliENST00000358859; ENSP00000351727; ENSG00000197651.
GeneIDi196477.
KEGGihsa:196477.
UCSCiuc001tbj.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCCER1_HUMAN
AccessioniPrimary (citable) accession number: Q8TC90
Secondary accession number(s): Q8TC47
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: June 1, 2002
Last modified: September 27, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations